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Molecular Diagnostics

Image: A prototype of the mobile diagnostic device developed by Sandia scientists and engineers for rapid detection of Zika and related viruses (Photo courtesy of Sandia National Laboratories / Randy Wong).

Mobile Device Rapidly Detects Zika and Related Viruses

A team of biologists and engineers have developed a smartphone-controlled, battery-operated, low-weight diagnostic technology that costs as little as USD 100 and can detect Zika, dengue, and chikungunya viruses within 30 minutes. The same platform can also be adapted to detect other human or animal pathogens. More...
31 Mar 2017
Image: New findings suggest that certain circulation microRNAs could serve as markers to help identify patients less likely to benefit from ablation therapy (Photo courtesy of Intermountain Medical Center).

Markers Predict Recurrence of Atrial Fibrillation after Ablation

Study suggests that certain circulating microRNA molecules are associated with the recurrence of the abnormal erratic heartbeats in some patients after ablation procedure, potentially providing markers that may help identify such patients in advance, as ablation therapy carries some risks and is expensive. More...
30 Mar 2017
Image: A micrograph of prostatic adenocarcinoma (conventional, acinar type) with perineural invasion. Prostate biopsy, H&E stain (Photo courtesy of Wikimedia).

Gene Mutations Associated with Aggressive Prostate Cancer

An international study has identified inherited genomic DNA mutations in the Kallikrein 6 (KLK6) gene region that are connected to a predisposition for some men to develop aggressive prostate cancer (PC). More...
28 Mar 2017
Image: New research shows the gene Cadherin 2 can lead to sudden death among young people and athletes with genetically inherited ARVC (Photo courtesy of Flipboard).

Gene Discovered Can Cause Sudden Cardiac Death

Researchers have found that mutations in the gene Cadherin 2 (CDH2) can lead to sudden death among young people and athletes with genetically inherited arrhythmogenic right ventricular cardiomyopathy (ARVC), which predisposes patients to cardiac arrest and is a major cause of unexpected death in seemingly healthy young people. More...
22 Mar 2017
Image: The structure of the CDH2 (cadherin 2) protein (Photo courtesy of Wikimedia Commons).

Genome Researchers Identify Mutation Linked to Cardiac Disorder

An international team of genome researchers has identified a gene variant linked to the potentially lethal cardiac disorder ARVC (Arrhythmogenic right ventricular cardiomyopathy). More...
22 Mar 2017
Image: The structure of the SEMA4D protein (Photo courtesy of Wikimedia Commons).

Mutation Linked to Obesity Identified in Genome Study

Results obtained during what was probably the first genome-wide association study (GWAS) for body mass index (BMI) to be conducted in continental Africa identified a gene, carried by about 1% of West Africans, linked to hereditary obesity. More...
21 Mar 2017
Image: Researchers say those who have a genetic disposition for storing fat deposits primarily at their waistline are at a higher risk of developing diabetes and coronary heart disease (Photo courtesy of Massachusetts General Hospital).

Body Type Can Increase Risk of Heart Disease and Diabetes

Researchers have identified a pattern of gene variants associated with an “apple-shaped” body type, in which weight is deposited around the abdomen rather than in the hips and thighs, increases risk for type 2 diabetes and coronary heart disease, as well as the incidence of several cardiovascular risk factors. More...
17 Mar 2017
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