Molecular Diagnostics
Combined Use of Assays Identifies Cancer Patient Response to Crizotinib
In screening of a large cohort for anaplastic lymphoma kinase (ALK) fusions through both fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) assays, researchers found many non-small cell lung cancer (NSCLC) patients who had negative and atypical FISH patterns accompanied with positive IHC results, who showed response to crizotinib treatment. More...19 Sep 2016
Blood Test Detects New Breast Cancer Subtype
A blood test has been developed that detects when the most common form of breast cancer has become resistant to treatment could double the average time it takes for the disease to progress, from around two and a half to around six months. More...14 Sep 2016
Rapid Molecular Diagnostic Test Detects Zika Virus
Zika virus has only recently gained attention due to recent large outbreaks worldwide and an easy to use nucleic acid amplification test (NAAT) could play an important role in the early detection of the infection and patient management. More...14 Sep 2016
Genetic Polymorphism Associated with Increased Cardiovascular Mortality
The platelet-derived growth factor (PDGF) family performs a multitude of functions such as vasodilation, regulation of erythropoiesis, and wound repair, but are also major mitogens for fibroblasts and smooth muscle cells, and are involved in the atherosclerotic process in the body. More...13 Sep 2016
New Method Simplifies Blood Biomarker Discovery and Analysis
A new gene expression analysis method has been developed to widen the usage of blood in biomarker discovery and analysis and the majority of the cells are erythrocytes that carry oxygen, causing 50% to 80% enrichment of globin ribonucleic acid (RNA) molecules among all blood RNA. More...08 Sep 2016
Fatal Fungal Infection Has Unique Growth Patterns
The multidrug-resistant yeast Candida auris, which has caused fatal infections in some hospitalized patients, has at least two different growth patterns and some of its strains are as capable of causing disease as the most invasive type of yeast called Candida albicans. More...08 Sep 2016
New Types of African Salmonella Associated with Lethal Infection
The first global-scale genetic study of Salmonella enteritidis bacteria, which is a major cause of blood poisoning and death in Africa and food poisoning in the Western World, has discovered that there are in fact three separate types. More...07 Sep 2016
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In Other News
First Epigenetic Signature Test to Classify Metastasis Tumors of Unknown Origin
Inherited Genetic Variant Increases Risk of Chronic Lymphocytic Leukemia
Immune Analysis of Biopsies Predicts Response to Melanoma Immunotherapy
Genetic Analysis of Lesions Provides Accurate Esophageal Cancer Test
Molecular Testing Accuracy for Clostridium difficile Scrutinized
Study Leads to Improved Diagnosis of Inherited Heart Muscle Disease
Early Detection Identified for Leukemia Patients' Resistance to Therapy
Cell-Free DNA Sequencing Confirms Myelodysplastic Syndrome Diagnosis
Simple Sensitive Assays Used for Analyzing Fragile X Syndrome
Droplet Digital PCR Rapidly Detects Alpha-Thalassemia Variants
Parkinson's Disease Risk Indicators Found in Diverse Tissues
Biomarker of Aggressive Prostate Cancer Discovered
Sequins As Novel Internal Controls to Improve Genomic Analysis
Novel Gene Discovered for Hereditary Colon Cancer
Gene Testing Simplified for Women with Ovarian Cancer
Gene Panel Predicts Damage in Donated Kidneys
HPV Test Approved for Use with SurePath Preservative Fluid
Direct Molecular Detection of Bloodstream Infection Evaluated
Red Hair Genetics Drive Up Skin Cancer Mutations
Liquid Biopsies Offer New Hope for Treatment and Tracking of Ovarian Cancer
Newly Described Intellectual Disability Syndrome Caused by Damage to Single Gene
Genetic Mutations Linked to Rare Multiple Bowel Tumors
New Genetic Mutation Linked to Osteonecrosis of the Hip
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.