Molecular Diagnostics
Direct Molecular Detection of Bloodstream Infection Evaluated
Blood culture is the current gold standard for detecting bacteria in blood, requires at least 24 to 48 hours and has limited sensitivity if obtained during antibiotic treatment of the patient. Severe sepsis is sepsis associated with organ dysfunction, hypoperfusion, or hypotension. More...02 Aug 2016
Red Hair Genetics Drive Up Skin Cancer Mutations
An international research team has shown that gene variants associated with red hair, pale skin, and freckles are linked to a higher number of genetic mutations in cutaneous melanoma cancers. The burden of mutations associated with these variants is comparable to an extra 21 years of sun exposure in people without this variant. More...01 Aug 2016
Liquid Biopsies Offer New Hope for Treatment and Tracking of Ovarian Cancer
Researchers are developing a new approach that could enable early detection, monitoring, and treatment for ovarian cancer (OC) that reoccurs in patients in remission: they found that liquid biopsies from blood tests and DNA sequencing can detect OC recurrence long before a tumor reappears. More...01 Aug 2016
Newly Described Intellectual Disability Syndrome Caused by Damage to Single Gene
Scientists have discovered that the gene for transcription factor BCL11A is responsible for a previously unidentified intellectual disability and have identified a mechanism by which loss-of-function BCL11A mutations can lead to cognitive disability. The findings could lead to new targeted therapies and diagnostic tests for this disorder. More...01 Aug 2016
Genetic Mutations Linked to Rare Multiple Bowel Tumors
Most people with colorectal cancer will develop one primary tumor, which may then multiply and spread; however, in around 2% to 5% of colorectal cancer (CRC) cases, two primary tumors will originate and develop independently, known as synchronous colorectal cancer. More...28 Jul 2016
New Genetic Mutation Linked to Osteonecrosis of the Hip
Osteonecrosis or 'bone death' of the femoral head is a disease caused by interruption of blood flow in the hip bone and patients, many of whom are under the age of 25, experience pain and the bone and surrounding joint collapse. More...27 Jul 2016
Exposure to Toxins in Children Associated with Kidney Disease Biomarker
Researchers have assessed environmental exposure to multiple toxins in children living in a region of Mexico with a high incidence of chronic kidney disease, especially among young adults. They not only detected high levels of arsenic and chromium in urine samples, they also detected elevated levels of Kidney Injury Molecule-1 (KIM-1), a biomarker currently being studied as an early sign of kidney injury. More...26 Jul 2016
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In Other News
Common Circulating Cell Clusters in Cancer Patients Characterized Anew
Genetic Findings Explain Inherited Predisposition to Myeloma
FDA Supports Expanded Claims for Carbapenem Resistance Test
Parkinson's Disease Biomarker Found in Urinary Samples
Low-Cost Genetic Test Can Distinguish Bacterial from Viral Infections
Rapid Genetic Test Developed for an Often Fatal Mitochondrial Disease
Detection of Circulating Tumor DNA Predicts Colon Cancer Recurrence
Genetic Causes of Bowel Cancer Clarified
Plasma Mannose Levels May Indicate Diabetes Risk
Celiac Disease Triggered by Intestinal Viruses
Circulating MicroRNAs Predict Future Fatal Myocardial Infarction
Spatial Transcriptomics Technique Enables Visualization of Gene Expression in Tissues
MicroRNAs Predict Disease Progression in Brain Tumors
Automated Extraction of FFPE Tissue for High-Risk HPV Testing
Lung Pathogens Detected Faster by Molecular-Based Method
Unsuspected Bacterial Link to Bile Duct Cancer Discovered
Faulty Genetic Instructions Drive Deadly Leukemia in Adults
Brain Infections Diagnosed Using Next-Generation Sequencing
Liquid Biopsy Biomarkers for Aggressive Prostate Cancer Discovered
Biochip Combines Graphene Electronics and DNA Strand Displacement for Detection of Polymorphism Mutations
Multiplex Molecular Test Developed for Three Arboviruses
Liquid Biopsy Urine Test Detects Mutations In Lung Cancer
Earliest Stage of Human Immunodeficiency Virus Infection Analyzed
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.