Molecular Diagnostics

Non-Invasive Prostate Cancer Test Developed Using Exosomal RNA
The current screening paradigm for prostate cancer faces challenges that lead to unnecessary biopsies and, ultimately, overtreatment. The disadvantage of Prostate-Specific Antigen (PSA) testing is lack of specificity for prostate cancer resulting in both false positive and false negative results. More...11 May 2016

Field-Applicable Molecular Test Diagnoses Tegumentary Leishmaniasis
Cutaneous and mucosal leishmaniases are widely distributed in Central and South America. Leishmania of the Viannia subgenus are the most frequent species infecting humans. L. (V.) braziliensis, L. (V.) panamensis are also responsible for metastatic mucosal leishmaniasis. More...11 May 2016
Bacterial Vaginosis Assessed By Molecular Methods
Bacterial vaginosis (BV) is an aberrant state of the vaginal microbiota, which is characterized by a depletion of lactobacilli, an increased diversity of the bacterial population and an elevated pH. It is one the most common vaginal syndromes in fertile, premenopausal and pregnant women. More...11 May 2016
Novel Multiplexed Digital Immunohistochemistry Used On Tissue Sections
Intratumoral heterogeneity has emerged as a critical challenge to the implementation of targeted therapeutics and immunohistochemistry (IHC) has been used to assess spatial heterogeneity of proteins; however, it has been difficult to quantify protein abundance at high multiplex and wide dynamic range. More...10 May 2016

New Strategy Broadens Detection of Breast & Ovarian Cancer Gene Variants
Using next generation sequencing (NGS) technology and information theory (IT), researchers have developed a new method for identifying mutations and prioritizing sequence variants related to hereditary breast and ovarian cancer (HBOC). This could not only reduce the number of possible variants to test for, but also increase the number of patients that are properly diagnosed. More...09 May 2016

In Other News
Noninvasive Test Detects Colorectal Cancer in Unscreened Patients
Patterns of MicroRNA Expression Distinguish Patients with Asthma and Allergic Rhinitis
Genetic Link Confirmed Between DCIS And Invasive Disease
DNA-Based Test Determines Degree Of Liver Fibrosis
Genomics Makeup of Colorectal Tumors Predicts Immune Response
Pathway Implicated in Development of Eosinophilic Esophagitis
Blood Test Detects Genetic Mutations in Lung Cancer
Genetic Testing for Breast Cancer Patients Expanded
Blood Test Evaluated for Suspected Obstructive Coronary Artery Disease
Association Found Between MC1R Variant and Melanoma Risk
Prostate Needle Biopsy Biomarker Predicts Tumor Aggressiveness
Gene Test Identifies Patients with High Risk Colon Cancer
Improved “Liquid Biopsy” Technique Enhances Tumor DNA Detection
Establishment of Biomarker Panel May Lead to Rapid Tests for Early Diagnosis of Pancreatic Cancer
Genomic Sequencing Identifies Deadly Bloodstream Infection
Noncoding RNA Gene Linked to Malignant Melanoma
Novel Blood Test Detects Colorectal Cancer Recurrence Earlier
Hereditary Cancer Test Identifies Deleterious Mutations in Endometrial Cancer
Multigene Test Identifies Early Breast Cancer
Blood Test Gives Early Warning of Melanoma Relapse
Robust Method Developed for Microbiome Analysis
Biomarker Identifies Uveal Melanoma Patients at Risk for Metastasis
Ultrasensitive Antibody Detection Enabled by Agglutination-PCR
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.








