Molecular Diagnostics


Noninvasive Test Detects Colorectal Cancer in Unscreened Patients
A noninvasive colorectal cancer-screening test detected the disease in patients who had previously avoided more invasive screening measures. Colorectal cancer is the second deadliest form of cancer in the USA and this year, nearly 135,000 Americans will be diagnosed with the disease and 50,000 Americans will die of it. More...03 May 2016
Patterns of MicroRNA Expression Distinguish Patients with Asthma and Allergic Rhinitis
Subsets of circulating micro RNAs (miRNAs) are uniquely expressed in asthmatic patients and in patients with allergic rhinitis (AR) and have potential for use as noninvasive biomarkers to diagnose and characterize these diseases. More...29 Apr 2016

Genetic Link Confirmed Between DCIS And Invasive Disease
Inherited genetic links have been confirmed between non-invasive cancerous changes found in the milk ducts, known as ductal carcinoma in situ (DCIS) and the development of invasive breast cancer, meaning that a family history of DCIS could be as important to assessing a woman's risk as a history of invasive breast cancer. More...28 Apr 2016

DNA-Based Test Determines Degree Of Liver Fibrosis
Non-alcoholic fatty liver disease (NAFLD) accounts for the majority of liver disease burden in the Western world. Liver biopsy remains the gold standard test to accurately stage fibrosis in patients with NAFLD, but it is invasive and carries risks. More...28 Apr 2016

Genomics Makeup of Colorectal Tumors Predicts Immune Response
A study based on whole-exome sequencing and immune response finds that colorectal cancers (CRCs) heavily bedecked with tumor-related neoantigens are likely to be permeated with disease-fighting white blood cells (WBCs). The discovery helps sharpen research into therapies that make tumors more vulnerable to such an attack and into companion diagnostics. More...27 Apr 2016

Pathway Implicated in Development of Eosinophilic Esophagitis
Scientists have identified a protein whose dysfunction appears to be involved in causing the tissue damage in patients with eosinophilic esophagitis (EoE). The finding may lead to improved pathology analysis, diagnostics, and specific drug therapies for patients. More...26 Apr 2016
In Other News
Blood Test Detects Genetic Mutations in Lung Cancer
Genetic Testing for Breast Cancer Patients Expanded
Blood Test Evaluated for Suspected Obstructive Coronary Artery Disease
Association Found Between MC1R Variant and Melanoma Risk
Prostate Needle Biopsy Biomarker Predicts Tumor Aggressiveness
Gene Test Identifies Patients with High Risk Colon Cancer
Improved “Liquid Biopsy” Technique Enhances Tumor DNA Detection
Establishment of Biomarker Panel May Lead to Rapid Tests for Early Diagnosis of Pancreatic Cancer
Genomic Sequencing Identifies Deadly Bloodstream Infection
Noncoding RNA Gene Linked to Malignant Melanoma
Novel Blood Test Detects Colorectal Cancer Recurrence Earlier
Hereditary Cancer Test Identifies Deleterious Mutations in Endometrial Cancer
Multigene Test Identifies Early Breast Cancer
Blood Test Gives Early Warning of Melanoma Relapse
Robust Method Developed for Microbiome Analysis
Biomarker Identifies Uveal Melanoma Patients at Risk for Metastasis
Ultrasensitive Antibody Detection Enabled by Agglutination-PCR
Whole-Exome Sequencing Identifies Rare Inherited Diseases
Gene Predicts Outcomes for Head and Neck Patients
Genomic Analyses Identifies Molecular Subtypes of Pancreatic Cancer
Biomarkers Help Diagnose Mild Cognitive Impairment in Diabetics
New Protocol Rapidly Detects Three Legionella Species
Blood Test Developed to Detect Five Early-Stage Cancers
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.








