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Molecular Diagnostics

Image: A scanning electron micrograph (SEM) of prostate cancer cells (Photo courtesy of David McCarthy).

Tumor Marker Levels Serve As Indicators of Disease Progression

Measuring serum levels of tumor markers may serve as an early indicator of the progression of established tumors in the face of ongoing treatment. More...
19 Sep 2017
Image: The VITEK 2 COMPACT instrument offers the capacity to help improve therapeutic success and patient outcomes through reliable microbial identification (ID) and antibiotic susceptibility testing (AST) (Photo courtesy of bioMérieux).

Newly Emerged Superbug Discovered

Hypervirulent Klebsiella pneumoniae strains often cause life-threatening community-acquired infections in young and healthy hosts, but are usually sensitive to antibiotics. More...
15 Sep 2017
Image: A photomicrograph showing hypertrophic decidual vasculopathy, a finding seen in gestational hypertension and pre-eclampsia (Photo courtesy of Nephron).

Risk of Preeclampsia Linked to Fetal Genes

Preeclampsia affects around 3% of births in Norway; worldwide, that number is estimated to be about 5%. For the first time, a relationship has been found between fetal genes and the risk of preeclampsia in the mother. More...
15 Sep 2017
Image: The GeneXpert MTB/RIF Ultra assay for tuberculosis; this new test is critical in allowing clinicians improved diagnostic interpretation (Photo courtesy of Cepheid).

New Diagnostic Test Improves Detection of Tuberculosis

Tuberculosis (TB) remains a global health threat despite the development of new diagnostics and antitubercular drugs. The MTB/RIF assay was developed to improve TB and rifampin resistance (RIF-R) detection. More...
14 Sep 2017

Gene Related to Abnormal Brain Development Identified

Using integrative genomics of brain cells, researchers have identified a gene thought to be associated with the types of brain damage that can be caused by inflammation during premature birth, suggesting the presence of a previously unknown mechanism of brain injury. More...
13 Sep 2017
Image: The gene variant, with a single amino acid switch from alanine to threonine in the brain-expressed G-protein coupled recepter CX3CR1, causes disruption of Akt signaling (Photo courtesy of Osaka University).

Gene Mutation Increases Risk of Neurodevelopmental Disorders

Researchers have found that a rare variant of the G protein-coupled receptor CX3CR1, due to only a single amino acid substitution, may become useful in predicting increased risk for developing schizophrenia and autism. More...
12 Sep 2017

Serum Level Measurements Improve Disease Risk Prediction

Results obtained by using a commercially available uromodulin ELISA kit to analyze serum samples from individuals at risk for heart and circulatory system diseases indicated that this kidney-specific protein is a biomarker not only for kidney disease but also for cardiovascular diseases. More...
12 Sep 2017
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