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Molecular Diagnostics

Image: Activation of the brain\'s fear network visualized using functional magnetic resonance imaging (MRI) (Photo courtesy of Dr. Tina Lonsdorf, Systems Neuroscience UKE Hamburg).

New Genetic Risk Factor Identified for Anxiety Disorders

Several newly discovered variants of the GLRB gene were associated with increased risk of developing anxiety disorders, including agoraphobic cognitions, increased startle response, and fear network activation, pointing to a potential neurogenetic pathway. More...
11 Apr 2017
Image: A representation of the molecular structure of KDR (kinase insert domain receptor) protein (Photo courtesy of Wikimedia Commons).

Targeted Microbubbles Enhance Ultrasound Detection of Malignant Tumors

By combining standard ultrasound technology with a novel type of targeted microbubbles, cancer researchers have developed a sensitive method for detecting malignant tumors that could reduce the number of biopsies needed to differentiate them from benign growths. More...
11 Apr 2017
Image: A molecular model of human papillomavirus (HPV) (Photo courtesy of Wikimedia Commons).

Mutations Linked to Improved Survival of Patients with HPV+ Carcinoma

Cancer researchers analyzed head and neck squamous cell carcinoma (HNSCC) data from The Cancer Genome Atlas to identify molecular characteristics of human papillomavirus (HPV)+ HNSCC and correlated them with patient outcomes. More...
11 Apr 2017
Image: The NanoSight NS300 instrument provides an easy-to-use, reproducible platform for nanoparticle characterization (Photo courtesy of Malvern Instruments).

Test Discovered for Earlier Detection of Transplant Rejection

A method has been discovered that appears to provide earlier warning of organ transplant rejection compared to standard methods, and requires only a blood test rather than a more invasive and painful needle biopsy. More...
06 Apr 2017
Image: An MRI scan of a human brain (Photo courtesy of the Institute of Cancer Research, London).

Cancer Study Reveals Insights to Causes and Inherited Risk

In a largest-to-date genomics study of brain cancer, researchers have uncovered treasure trove of information about genetics underlying the most common form of brain cancer – glioma. They were able to identify mutations that increase susceptibility, and assess more specific associations with developing one or the other of the two main glioma subtypes. More...
04 Apr 2017
Image: A genetic variant within the gene for protein tyrosine phosphatase receptor-type delta (PTPRD) has been associated to susceptibility to neurofibrillary tangles, which are thought to be more closely related to memory decline than other forms of aging-related brain pathologies (Photo courtesy of Rush University).

Gene Discovered Associated with Aging Brain Pathologies

Investigators have discovered a gene associated with susceptibility to the common Tau form of brain pathology that accumulates in several different conditions, including Alzheimer’s disease, certain forms of dementia, and Parkinsonian syndromes, as well as chronic traumatic encephalopathy that occurs with repeated head injuries. The gene and its product may serve as a marker for loss of brain function with advancing age, and as a potential drug therapy target. More...
04 Apr 2017
Image: Controlling magnetic nanoparticles through a microfluidic chip – produced by the rapid prototyping method – with the aid of magnets that are arranged above and below the microfluidic chip (Photo courtesy of the Fraunhofer Institute for Cell Therapy & Immunology).

Lab-on-a-Chip Platform Designed for Detection of Pathogens

A team of German bioengineers has developed an integrated and automated lab-on-a-chip platform for sample preparation and nucleic acid-based detection of pathogens in various liquid media. More...
04 Apr 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.