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Molecular Diagnostics

Biomarker Signatures Predict Aging Health Quality

A panel of 19 biomarkers in the blood was utilized to create molecular signatures that are able to predict how well an individual is aging and how severe the likelihood that he or she will develop an aging-related disease. More...
17 Jan 2017

Susceptibility Genes Distinct from Severity Genes in Crohn's Disease

The group of 170 gene variants that have been linked to the development of Crohn's disease has been found to operate independently from a second group of four variants, which determines how severe the disease will be. More...
17 Jan 2017
Image: The BD LSR II flow cytometry analyzer (Photo courtesy of BD Bioscience).

Genetic Test Determines Patients Sensitivity to Cancer Drug

The identification of genetic biomarkers of synthetic lethal drug sensitivity effects provides one approach to the development of targeted cancer therapies. Testing for a gene commonly mutated in ovarian cancers could pick out patients who will respond well to a promising new class of cancer drugs. More...
12 Jan 2017
Image: The Wizard SV Genomic DNA purification system (Photo courtesy of Promega).

Genomic Sequencing Illuminates Recent Shigellosis Outbreaks

Shigellosis is an acute gastrointestinal infection caused by bacteria belonging to the genus Shigella. Shigellosis is the third most common enteric bacterial infection in the USA with 500,000 infections, 6,000 hospitalizations, and 70 deaths each year. More...
12 Jan 2017
Image: An infant suffering from congenital hypotonia or muscle weakness (Photo courtesy of American Academy of Pediatrics).

Genetic Cause Identified for Previously Unrecognized Developmental Disorder

An international team of scientists has identified variants of the gene Early B-Cell Factor 3 (EBF3) causing a developmental disorder with features in common with autism. More...
11 Jan 2017
Image: Overview of the study pipeline beginning with collection of uterine lavage fluid at the initiation of hysteroscopy (Photo courtesy of Icahn School of Medicine at Mount Sinai).

Endometrial Cancer Mutations Detected in Uterine Lavage Fluid

Endometrial cancer is the most common gynecologic malignancy, and its incidence and associated mortality are increasing and despite the immediate need to detect these cancers at an earlier stage, there is no effective screening methodology or protocol for endometrial cancer. More...
11 Jan 2017
Image: The Biomark microfluidic system for polymerase chain reactions (Photo courtesy of Fluidigm).

DNA Levels in Blood Correlated with Ovarian Cancer Outcomes

The development of blood biomarkers that can be used for early detection of cancer or to measure tumor burden and response to treatment is a major goal of translational cancer studies across all cancer types. More...
04 Jan 2017
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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