Molecular Diagnostics
Disease Genes Effect May Be Overcome by Other Gene Mutations
A first-of-its-kind study, performed in the model yeast Saccharomyces cerevisiae, shows how “bad genes aren’t always bad news” in that the disease-causing effects of mutations in certain genes can be overcome by suppression-mutations in certain other genes. The study opens a new way for better understanding how some people naturally stay healthy despite having disease-causing mutations, and potentially a new path to better diagnostics and therapies of genetic disorders. More...15 Nov 2016
Vascular Development Gene Helps Protect Against Stroke Damage
Using CRISPR gene-editing technology and genetically engineered mice, scientists have discovered that a “collateral vessels” gene, Rabep2, protects against stroke damage. Variants of the human version of the gene may help explain why people differ so much in their ability to survive artery blockages. More...15 Nov 2016
Early Childhood Screening Helps Prevent Heart Attacks
Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels and is the main inherited cause of early heart disease and without preventive medication young FH adults has about a 10-fold increased risk of a heart attack before the age of 40. More...08 Nov 2016
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In Other News
Testing Method Clinically Ascertains Genetic Basis for Hypercholesterolemia
Gene Abnormality Found to Underlie Rare Neurological Disease
Non-Invasive Assay Improves Surveillance of Solid-Organ Transplants
Low Cost Method Examines Single Leukemic Cells
Commercial Molecular Assay Validated for Dengue Virus Outbreak
Blood Test for Colorectal Cancer Recurrence Proves Highly Sensitive
DNA-Based Analysis Detects Group A Streptococcus
Gene Activity Mapping Points to Two Subtypes of Crohn's Disease
Liquid Biopsy Tests Identified Cell-Free Tumor DNA Mutations
Simple Blood Test Vastly Improves Severe Liver Disease Detection
Strange Chimeras Defy Scientific Understanding of Human Genetics
New Genetic Links Identified for Heart Disease Risk Factors
Field Test Allows Rapid Diagnosis of Chikungunya Virus Infection
Quantitative Molecular Diagnostic Methods Identify Causes of Childhood Diarrhea
Genomic Fingerprinting Helps Predict Prostate Tumor Aggressiveness
Extended Multilocus Sequence Typing Developed for Leptospirosis
Genetic Cause Deciphered for Inherited Nerve Damage Afflicting Older Adults
DNA Analysis Clarifies Ancestry of Triple-Negative Breast Cancer Patients
New Genes Implicated in High Blood Pressure Regulation
New Standardized Whole Genomes Released to Improve Quality Control
Test Developed for Healthcare-Acquired Infections Validated
Tumor Analysis Method Identifies High-Risk Prostate Cancer
Rare Inflammatory Disease Identified in Children
Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
