Clinical Chemistry

Two Immunoassays Compared for Determination of Serum Vitamin D
Vitamin D is a fat-soluble steroid prohormone that is generated mainly in the skin by photochemical conversion of 7-dehydrocholesterol. 25-hydroxyvitamin D (25(OH)D) is its main storage form and is present in blood at very high concentration with respect to the active form 1,25-dihydroxyvitamin D. More...06 Jul 2021

Monocyte Distribution Width Evaluated as a Sepsis Indicator
Most current automated hematology analyzers have enhanced cell counting functions including the addition of new cell types such as nucleated red blood cells or immature granulocytes, making it possible to obtain a precise quantification of peripheral blood cells in pathological conditions. More...01 Jul 2021

Plasma Neurofilament Light Validated Biomarker for Neurological Conditions
In the management of neurological disorders, reliable and easily accessible biomarkers are needed to recognize or rule out an underlying neurodegenerative process contributing to cognitive decline at the earliest stage. More...30 Jun 2021

Diabetic Biomarkers Concordance Compared in South African Blacks
Sub-Saharan Africa is projected to experience a significant increase in the prevalence of diabetes mellitus by in the near future and accurate, comparable prevalence estimates will be essential to planning and monitoring by public health authorities. More...28 Jun 2021

Plasma ACE2 Predicts Prognosis of COVID-19 Hospitalized Patients
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a devastating global pandemic. The disease caused by SARS-CoV-2 infection has been termed coronavirus disease of 2019 (COVID-19) with clinical manifestations ranging from asymptomatic and subclinical infection to severe hyperinflammatory syndrome and death. More...24 Jun 2021


Hyperglycemia Evaluated as a Risk Factor in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (pancreatic cancer) has a five-year survival rate of 9%. Most patients are diagnosed with metastatic disease due to late presenting symptoms and only 10% to 20% are able to undergo surgery with a curative intent. More...23 Jun 2021
In Other News
Biomarker Predicts Crohn's Disease Relapse in Children
Serum Leptin Concentration Predict Cardiovascular Outcomes in Hemodialysis Patients
Urinary Sodium/Potassium Ratio Screens for Hyperaldosteronism in Hypertensive Men
Platelet Indices Analyzed for Tuberculosis and Diabetes Mellitus Co-Morbidity
Low-Density Lipoprotein Cholesterol Is Associated with Insulin Secretion
Serum Based Antigen Test Detects Childhood Tuberculosis
Low Sugar Metabolite Associated with Disability, Neurodegeneration in MS
Non‐Invasive Urine Markers Differentiate Renal Cancer from Oncocytoma
Serum Catestatin Level Is Increased in Women with Preeclampsia
Plasma-Based S100B Testing for Management of Traumatic Brain Injury
Novel Diagnostic Test Assesses Risk of Urinary Uric Acid Crystallization
Maternal Multiomic Changes Could Predict Onset of Labor
Meconium Microbiome Can Help Predict Risk of Developing Allergies
Maternal Free Thyroxine Associated with Gestational Diabetes
ANGPTL8 Levels Associated with Hyperlipidemia in Primary Nephrotic Syndrome
Altered Perivascular Fibroblast Activity Precedes ALS Disease Onset
Blood-Based Markers Tied to Brain Cell and Memory Loss
Serum α-L-Fucosidase Activity Measured for COVID-19 Infection
Urinary Heat Shock Protein 70 Evaluated in Chronic Prostatitis
Breath Test Determines Severity of Methylmalonic Acidemia Disease
Vitamin D Deficiency Linked to Metabolic Changes in Lupus Patients
Circulating Calprotectin as Biomarker in Neutrophil-Related Inflammation
Coagulation Dysfunction and Infection Evaluated in Patients with AECOPD
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.