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Clinical Chemistry

Image: Histopathology of a heart demonstrating fibrosis and myocardial disarray in hypertrophic cardiomyopathy from a case of sudden cardiac arrest (Photo courtesy of Candace H Schoppe, MD).

Sex Hormone Levels Linked to Sudden Cardiac Arrest Risk

The measurement of the levels of sex hormones in patients' blood may identify patients likely to suffer a sudden cardiac arrest, a heart rhythm disorder that can be fatal in most patients.  More...
15 Sep 2014
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Novel Method Identifies Fat Malabsorption

A novel clinical test known as the Serum Retinyl Palmitate Test has been assessed and validated for the diagnosis of fat malabsorption, and compared to the fecal fat test.  More...
10 Sep 2014
Image: The Zinc Transporter 8 Autoantibody (ZnT8Ab) enzyme-linked immunosorbent assay (ELISA) kit (Photo courtesy of KRONUS).

Autoantibody Test Helps Diagnose Type 1 Diabetes

The first zinc transporter 8 autoantibody test has been approved for marketing and the test can help determine if a person has diabetes mellitus type 1 and not another type of diabetes.   More...
09 Sep 2014
Image: The three year risk of type 2 diabetes by admission glucose. The solid line represents the estimate and the ribbon represents the 95% confidence intervals (Graph courtesy of the Public Library of Science).

Blood Glucose in Hospitalized Patients Predicts Diabetes Risk

Blood glucose levels measured in hospitalized adults during acute illness can be used to predict the risk of developing type 2 diabetes over the following three years.   More...
03 Sep 2014
Image: The new monitor uses a laser to read blood sugar levels. The laser is directed at the person\'s palm, passes through skin cells and is partially absorbed by sugar molecules, allowing scientists to calculate the level of blood sugar (Photo courtesy of Princeton University, Engineering School).

Noninvasive Glucose Sensing Uses Mid-Infrared Light

A laser has been developed to measure people's blood sugar, and the technique could allow diabetics to check their condition without pricking themselves to draw blood.   More...
01 Sep 2014
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Genetic and Lifestyle Factors Effect Biomarker Variation

Ideal biomarkers used for disease diagnosis should display deviating levels in affected individuals only and be robust to factors unrelated to the disease.  More...
01 Sep 2014
Image: The Jasco UV/Vis 530 spectrophotometer (photo courtesy of Jasco Analytical Instruments).

Micro-Method Determines Glutathione in Human Blood

A new colorimetric procedure has been described for the visible-range spectrophotometric analysis of glutathione in microvolumes of blood collected by fingerstick and validated by reliable high-performance liquid chromatography.  More...
27 Aug 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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