Clinical Chemistry


Protein Patterning: Novel Tool for Studying Sepsis
In a new approach using quantitative targeted proteomics, researchers have for the first time developed a way to use mass-spectrometry to measure hundreds of organ proteins in a single blood sample. The resulting protein patterns can help determine sepsis severity, which organs have been damaged, and may lead to faster diagnostics. More...18 Jan 2016

Hyaluronic Acid Turbidimetric Assay Compared to Standard Method
Circulating hyaluronic acid in human adults is primarily produced in the peripheral soft connective tissue and transported to the systemic circulation via lymph drainage and the majority of HA is removed from circulation by hepatic elimination. More...13 Jan 2016


Prediabetes Linked to Early Kidney Damage
The role of prediabetes as a risk factor for hyperfiltration and albuminuria in persons who do not develop diabetes is unclear and the lack of evidence is mainly due to the difficulty of accurately assessing the glomerular filtration rate in the near-normal range of GFR. More...10 Jan 2016

Commercial Assay Aids Physicians in Tamoxifen Drug Monitoring
A laboratory developed test could help assess levels of several tamoxifen drug metabolites in a blood specimen which is important as five years of therapy with tamoxifen has been the standard of care for women with early stage, estrogen-receptor-positive breast cancer following "curative" surgery. More...30 Dec 2015

Simple Test of Kidney Function Needs More Consideration
Kidney disease in the USA and other parts of the world is both common and under-diagnosed, but new studies suggest that paying close attention to results of a simple blood test can help predict the likelihood that patients will develop kidney failure. More...29 Dec 2015
In Other News
New Method Diagnoses Deadly Fungal Lung Infection
Prostate Cancer Screening Improved by Repeating Abnormal Tests
Elevated Sex Hormone Levels Raise Risk of Uterine Fibroids
New Assays to Measure Immunosuppressive Drugs Now Available
Low Zinc May Indicate Potential Breast-Feeding Problems
Overtesting for Diabetes Tends to Reap Negative “Rewards”
Blood Test Could Predict Rheumatoid Arthritis Risk
New Set of External Quality Assessment Programs Launched
ELISA Kit Used to Measure Predictive Marker for Diabetic Kidney Disease
Combining Tests Leads to Better Prediabetes Detection
Biomarker of Early-Stage Lung Cancer Identified
Portable Sensor Rapidly Determines Extent of Eye Injury
Novel Technology Diagnoses Stroke Quickly
Urine Sample Collection Tubes Relaunched for Microbial Diagnostics
Novel Device Measures Glucose in Urine
Protein Biomarkers Identified for Dysglycemia Cardiovascular Risk
Glycated Albumin Is a Promising Marker for Diabetes
Buruli Ulcer Diagnosed by Fluorescent Thin Layer Chromatography
Rheumatoid Arthritis Test Predicts Patient Response to Drugs
Childhood Concussions Detected by Blood Test
New Test Significantly Improves Prostate Cancer Screening
Low Vitamin D Levels May Harm Heart Health
Early Warning Biomarker Found for Chronic Kidney Disease
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.