Clinical Chemistry

Age Alters Diagnostic Performance of Cardiac Troponin
The guideline-recommended thresholds for increased high-sensitivity cardiac troponin I (hs-cTnI), indicating myocardial injury and potential infarction, performed at a similar sensitivity around 80% in people across age groups. More...20 Sep 2022

Low Testosterone Levels Tied to More Severe COVID in Men
The COVID-19 pandemic has exacted a heavy toll on public health. Male sex is associated with severe COVID-19. It is not known whether the risk of hospitalization differs between men with hypogonadism, men with eugonadism, and those receiving testosterone therapy (TTh). More...12 Sep 2022

Osteopontin and Osteoprotegerin Investigated In Peripheral Artery Disease
Peripheral artery disease (PAD) is one of the many complications of systemic atherosclerosis and it is accompanied by high rates of cardiovascular diseases (CVD) morbidity and mortality. PAD is a common condition in which narrowed arteries reduce blood flow to the arms or legs. More...08 Sep 2022


Total Plasma Homocysteine Methods Evaluated
Homocysteine (HCY) is occasionally requested as a prognostic risk factor in patients with cardiovascular diseases. Homocysteine is an intermediary amino acid formed in methionine metabolism, with elevated total homocysteine (tHCY) is a biomarker of cardiovascular and cerebrovascular diseases. More...15 Aug 2022

Lipid Cutoffs Identified for CVD Risk in Young Adults Without Diabetes
The underlying pathogenesis and progression associated with nearly all cardiovascular diseases (CVDs) are predominantly of atherosclerotic origin that leads to the development of coronary artery disease, cerebrovascular disease, venous thromboembolism and, peripheral vascular disease, subsequently causing myocardial infarction (MI), cardiac arrhythmias or stroke. More...09 Aug 2022

In Other News
Mitochondrial Biomarker Predicts Type 2 Diabetes Risk
Bile Acid Profile in Severe Fibromyalgia Associated with Microbiome Changes
Novel Presepsin Assay Evaluated Using Automated Immunoanalyzer
Bone Turnover Markers Associated With Mortality Risk in Older Men
Mindray’s BS-600M Chemistry Analyzer with High Sigma Level Boosts Lab Performance
Mobile Kidney Disease Testing Device Measures Urine Albumin at POC
Thyroid Hormone Levels Linked to Liver Fibrosis in T2D
Simple Colorimetric Assay Determines Human Mercaptalbumin Concentration
Electrochemical Sensor Platform to Enable New Diagnostic Tests in Near-Patient Settings
Serum Irisin Predicts Development of Gestational Diabetes
Biomarkers of Collagen Turnover Investigated in Crohn’s Disease
Plasma Neurofilament Light Predicts All-Cause Mortality Risk
Cardiac Biomarkers Investigated in Acquired Refractory Thrombocytopenic Purpura Patients
Fully Automated FIT Analyzer Designed for Labs with High Fecal Testing Volumes
Serum Vimentin Predicts Mortality in Pediatric Severe Sepsis
Bladder Cancer Urine Test Eliminates Invasive Cystoscopy and Unnecessary Imaging
Very High HDL Associated With CV Mortality in CAD
Advanced Electrolyte Analyzer Offers Fully Automatic iCa2+ Analysis
Herpesvirus Infection May Increase the Risk of Developing Diabetes
New biochemistry analyzer helps labs realize full automation and maximum efficiency
Analytical Performance of Novel Glycated Albumin Assay Evaluated
Different Subtypes Defined In Small Cell Lung Cancer
Potential Biomarker Found for Sudden Infant Death Syndrome
The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.