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Clinical Chemistry

Diagnostic Tests for Acute Rhinosinusitis Infections Reviewed

Acute rhinosinusitis (ARS) is defined as inflammation of the paranasal sinuses caused by viral or bacterial infection, and typically presents with facial pain or pressure, purulent nasal discharge, fever, cacosmia or hyposmia, and double sickening. More...
28 Oct 2016
Image: About 15% of the people in the USA with hypothyroidism continue to feel sick despite following the standard of care (Photo courtesy of Rush University Medical Center).

Hypothyroidism Symptoms Linger Despite Medication and Normal Test Results

The ideal therapeutic goal in hypothyroidism would be to restore clinical and biochemical euthyroidism via physiologic thyroid hormone replacement. More...
28 Oct 2016
Image: A photomicrograph of a bone marrow showing stromal macrophages containing numerous red blood cells in their cytoplasm from a patient with hemophagocytic lymphohistiocytosis (Photo courtesy of Nephron).

Prognostic Factors in Children with HLH Investigated

Hemophagocytic lymphohistiocytosis (HLH) is a rare disease characterized by a rapidly fatal hematological disorder usually associated with malignancies and severe infections and it presents with prolonged high fever that could not be controlled by antibiotics. More...
27 Oct 2016
Image: Dr. Georgios Tsiminis in his photonics laboratory (Photo courtesy of the University of Adelaide).

Optical Sensor to Detect Vitamin B12 Deficiency

Researchers have developed the first optical sensor that can detect vitamin B12 in diluted human blood – and a first step towards a low-cost, portable, broadscale B12 deficiency test that would overcome limitations of current methods for monitoring levels in high-risk individuals and populations. More...
26 Oct 2016
Image: The Afinion C-reactive protein (CRP) test cartridge and Afinion AS100 analyzer (Photo courtesy of Alere).

Rapid Blood Test Can Rule Out Serious Childhood Infections

The care for acutely ill children has traditionally been a primary care responsibility, but increasing numbers are being seen in secondary care, but a simple decision rule and a finger prick to test blood, general practitioners can now detect serious infections in children very quickly. More...
19 Oct 2016
Image: A histopathology of non-alcoholic steatohepatitis (NASH) in a liver biopsy (Photo courtesy of SPL).

Simple Blood Test Vastly Improves Severe Liver Disease Detection

A new non-invasive method of predicting the risk of developing a severe form of liver disease could ensure patients receive early and potentially life-saving medical intervention before irreversible damage is done. More...
19 Oct 2016
Image: The Quantum Blue rapid test allow for the immediate measurement of fecal calprotectin (Photo courtesy of Bühlmann Laboratories).

Unnecessary Endoscopies Could Be Avoided with Fecal Blood Test

The majority of primary care patients referred for bowel endoscopy do not have significant colorectal disease (SCD), and are unnecessarily exposed to a small but realistic risk of severe endoscopy-associated complications. More...
14 Oct 2016
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.