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BioResearch

Drug Modulating the Sphingosine Molecular Pathway Prevents Chronic Intestinal Inflammation from Progressing to Colitis-Associated Cancer

A recently published study found that fingolimod, a drug currently approved for the treatment of multiple sclerosis, could potentially eliminate or reduce the progression of colitis-associated cancer. More...
24 Jan 2013

Sickle Cell Erythrocytes Kill Solid Tumors Resistant to Chemotherapy and Radiation

Sickle cell erythrocytes bind to and block blood vessels in the hypoxic microenvironment of solid tumors, and the reactive oxygen species they release act to destroy the tumor. More...
24 Jan 2013

Synchrotron X-Ray Crystallography Generates Insulin-Insulin Receptor Binding Images

The light generated by a state-of-the-art particle accelerator was used to capture X-ray crystallographic images of the three-dimensional interaction between insulin and its receptor. More...
24 Jan 2013
Image: Transmission electron microscopy image of a Streptococcus pyogenes cell experiencing lysis after exposure to the highly active enzyme PlyC (Photo courtesy of Daniel Nelson, UMD).

Quantifying the Size of Holes Antibacterial Compounds Create in Cell Walls

Faced with resistant bacteria, a potential alternative to traditional antibiotics is PlyC, a powerful enzyme that kills the bacteria that causes streptococcal toxic shock syndrome and strep throat. More...
23 Jan 2013

MicroRNA Blockage of a Single Protein Induces Fibroblasts to Differentiate into Neurons

Inhibition of the activity of PTB by a specific microRNA is sufficient to induce fibroblasts to differentiate into functional neurons. More...
23 Jan 2013

Life Technologies Acquires Dutch Protein Purification Company

Life Technologies has acquired BAC, a market leader in the discovery, development, and manufacture of protein purification products. More...
22 Jan 2013
Image: The most common jellyfish protein used in lab research glows green when illuminated with UV light (Photo courtesy of NA/TSRI).

Benchtop Technology Designed for Marking, Selecting Cells

Their new method allows scientists to add a marker to specific cells, so that these cells may be easily located and/or chosen from a larger cell population. More...
22 Jan 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.