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BioResearch

Image: The new Agilent TwisTorr 304 FS high-vacuum pump (Photo courtesy of Agilent).

New High-Vacuum Pump Provides Increased Reliability and Efficiency

A new, high-performance turbomolecular pump is the first high-vacuum pump featuring a novel floating-suspension system that enables dramatic improvements over current technology. More...
19 Feb 2013

Amlexanox Abolishes Consequences of Obesity in a Mouse Model

A well-established drug currently used to treat mouth ulcers and asthma in humans was found to dramatically affect the metabolism of obese mice by causing these animals to lose weight while eliminating symptoms of diabetes and fatty liver. More...
19 Feb 2013
Image: A model showing that TIP60/NuA4-dependent acetylation limits 53BP1 binding to histone H4 when present on the same histone H4 tail with the mark H4K20Me2, a recognition mark for 53BP1. A TIP60 deficiency would result in reduced H4 acetylation, and increased 53BP1 binding, thus blocking BRCA1 function at DNA double-strand breaks (Photo courtesy of Dr. Roger A. Greenberg, Perelman School of Medicine, University of Pennsylvania).

Histone Acetylation Determines Cellular DNA-Repair Strategy

A team of cancer biologists have identified the molecular signal that determines which repair mechanism will be used by a cell to repair broken double-strand DNA. More...
19 Feb 2013

Newly Synthesized Peptide Has Therapeutic Possibilities against Neurologic Diseases, Cancer, and Infectious Diseases

Scientists have engineered a peptide that has possibilities for drug development into agents for treating infections, neurodegenerative disorders, and cancer by triggering autophagy. More...
19 Feb 2013
Image: Camouflaged nanoparticles (yellow) cloaked in the membranes of white blood cells rest on the surface of an immune system cell (phagocyte, blue) without being recognized, ingested, and destroyed (Photo courtesy of Ennio Tasciotti lab, Methodist Hospital Research Institute).

Leukocyte-Like Nanoparticles May Revolutionize Targeted Drug Delivery

LeukoLike Vectors readily evade the immune system, crossing the biological barriers of the body and localizing at target tissues. More...
18 Feb 2013

Newly Developed Compound Protects Heart Cells During and After Infarction

Using two recently developed diverse compounds, scientists have been able to show in animal models that suppressing a specific enzyme protects heart cells and neighboring tissue against the debilitating injury incurred by heart attacks. More...
18 Feb 2013

Hybrid Protein Transports Experimental Drug for Lysosomal Storage Diseases Across the Blood-brain Barrier

A hybrid molecule was able to bind to LDL receptors on the endothelial cells that form the inside surface of capillaries in the blood-brain barrier  and was then transcytosed into the central nervous system. More...
18 Feb 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.