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BioResearch

Image: Contributing author Dr. Jung-Mo Ahn (Photo courtesy of the University of Texas at Dallas).

Novel Drug Interferes with Androgen Receptors and Blocks Prostate Cancer Growth

A novel, small molecule peptidomimetic drug called D2 interferes with the function of androgen receptors, blocking the androgen-induced proliferation of prostate cancer cells in vitro and inhibiting tumor growth in a mouse xenograft model. More...
14 Jun 2013

Drugs Inhibiting the KRAS Oncogene Suppress Growth of Pancreatic Tumors in Mouse Xenograft Model

Drugs that inhibit the activity of the enzyme GSK-3 alpha strongly suppress growth of human pancreatic tumor xenografts in mice as well as down regulate certain oncogenic NF-kappaB target genes. More...
14 Jun 2013
Image: The Dualmembrane Kit for identification and investigation of membrane protein interaction partners (Photo courtesy of Dualsystems Biotech AG).

System Detects Novel Interaction Partners for Membrane Proteins

A system detects interactions involving integral membrane proteins or membrane-associated proteins, facilitating the identification of novel interaction partners and the investigation of interaction domains. More...
14 Jun 2013
Image: The new SeqCap EZ Pure Capture Bead Kit (Photo courtesy of Roche Nimblegen).

Bead-Based Capture Kit Eases Enrichment and Cleanup of DNA Libraries

A newly released bead-based capture system was designed to provide genomic researchers with a sensitive and robust method for capture and purification of DNA sample libraries enabling high-quality targeted sequencing results. More...
13 Jun 2013

New Multichannel Pipette Facilitates High-Throughput RNA Isolation

A new advanced multichannel pipette facilitates procedures such as a solid phase extraction-microplate method for reproducible, high throughput isolation of high quality, DNA-free total RNA. More...
13 Jun 2013
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Intranasal Antibody Gene Transfer in Mice and Ferrets Protects Against Influenza Infection

Transmission of the influenza virus was blocked in animal models by a gene therapy technique that introduced a neutralizing antibody gene directly into the cells lining the nose and respiratory system. More...
13 Jun 2013

Antiautoimmune Drug Treatment Combined with Bone Marrow Transplant Cures Mouse Model of Type I Diabetes

Treatment with a drug to block autoimmune attack combined with transplantation of adult bone marrow cells or purified bone marrow progenitor cells restored the population of insulin-producing pancreatic beta cells and cured a mouse model of type I diabetes. More...
12 Jun 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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