We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

LabMedica

Download Mobile App
Recent News Expo Clinical Chem. Molecular Diagnostics Hematology Immunology Microbiology Pathology Technology Industry Focus

Prototype Microspectrometer Suitable for Lab-on-a-Chip Technologies

By LabMedica International staff writers
Posted on 12 Aug 2013
By passing a beam of light through a silicon chip pierced with randomly scattered holes investigators have developed a sensitive microspectrometer that may be adaptable for "lab-on-a-chip" applications.

Investigators at Yale University (New Haven, CT, USA) reported in the July 28, 3013, online edition of the journal Nature Photonics that they had built a spectrometer based on multiple light scattering in a silicon-on-insulator chip featuring a random structure. A probe signal diffused through the chip generating wavelength-dependent speckle patterns, which were detected and used to recover the input spectrum after calibration. A spectral resolution of 0.75 nanometers at a wavelength of 1,500 nanometers in a 25-micrometer-radius structure was achieved.

Image: Yale University researchers have developed an ultracompact, low-cost spectrometer with improved resolution over existing micro models. The innovation represents an advance in “lab-on-a-chip” technology, or the consolidation of laboratory capabilities in miniature, highly portable devices (Photo courtesy of Yale University).
Image: Yale University researchers have developed an ultracompact, low-cost spectrometer with improved resolution over existing micro models. The innovation represents an advance in “lab-on-a-chip” technology, or the consolidation of laboratory capabilities in miniature, highly portable devices (Photo courtesy of Yale University).

“The largest dimension of our spectrometer, which we built on a silicon chip, is about the width of a human hair,” said first author Dr. Brandon Redding, a postdoctoral associate in applied physics at Yale University. “It could open up a whole new range of uses, a lot of them outside the lab.”

The microspectrometer can detect a change in wavelength of less than one nanometer, roughly matching the capability of macroscopic spectrometers about the size of a hard drive. “We were taking a very different approach,” said Dr. Redding. “The idea of using disorder and multiple scattering is a fairly unexplored concept. Normally, disorder is something you want to overcome or avoid. In this case, it is what lets us make the device so small. We get a much longer path length for our light relative to the size of the device, because the light bounces around many times.”

The authors maintain that a compact, high-resolution spectrometer, such as that described in this study, is well suited for lab-on-a-chip spectroscopy applications.

Related Links:

Yale University




Platinum Member
COVID-19 Rapid Test
OSOM COVID-19 Antigen Rapid Test
Magnetic Bead Separation Modules
MAG and HEATMAG
POCT Fluorescent Immunoassay Analyzer
FIA Go
Gold Member
Fully Automated Cell Density/Viability Analyzer
BioProfile FAST CDV

Latest BioResearch News

Genome Analysis Predicts Likelihood of Neurodisability in Oxygen-Deprived Newborns

Gene Panel Predicts Disease Progession for Patients with B-cell Lymphoma

New Method Simplifies Preparation of Tumor Genomic DNA Libraries