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BioResearch

Image: Comparison of the organoid (right) to the developing brain (left, section of a mouse brain) (Photo courtesy of the Institute of Molecular Biotechnology of the Austrian Academy of Sciences).

Stem Cell-Based Cerebral Organoids Enable in Vitro Study of Human Brain Development and Microcephaly

Austrian researchers have used advanced stem cell technology to grow cultures of cerebral organoids, or "mini-brains," which enable the in vitro study of human neuronal disorders. More...
09 Sep 2013
Image: Researchers have identified the protein RbAp48, that, when increased in aged wild-type mice, improves memory back to that of young wild-type mice. In the image, yellow shows the increased RbAp48 in the dentate gyrus (Photo courtesy of Dr. Elias Pavlopoulos, Columbia University Medical Center).

Gene Expression Study Confirms Age-Related Memory Loss Is Distinct from Alzheimer's Disease

Decline in the activity of the gene that codes for the protein RbAp48 in the hippocampus has been linked to age-related memory loss, a condition not related to Alzheimer's disease. More...
05 Sep 2013

Blocking Ether Lipid Synthesis Prevents Tumor Growth

Tumor cells have elevated levels of ether lipids, and blocking the activity of an enzyme critical to their synthesis was found to have profound anticancer benefits. More...
04 Sep 2013

New Software Tool Identifies Driver Genes and Pathways in Cancer Sequencing Studies

Cancer researchers have developed a software tool that enables them to identify the driver mutations that underlie the transformation of normal cells and tissues into malignancies. More...
03 Sep 2013
Image: iTaq Universal SYBR Green Supermix (Photo courtesy of Bio-Rad).

New Line of DNA Amplification Reagents Promises Consistent Results Across All PCR Instruments

New reagent mixes specially formulated for PCR applications are now available for biotech and genomics researchers. More...
02 Sep 2013

Rose Bengal-Based Drug Kills Both Primary and Secondary Melanoma Tumors

Drug developers have discovered the immunological mechanism that underlies the ability of the candidate drug PV-10 to induce regression of primary and secondary melanoma tumors. More...
02 Sep 2013
Image: RNA-Guided Nucleases (RGNs), based on naturally occurring Type II CRISPR-Cas systems, are programmable endonucleases that can be used to perform targeted genome editing (Photo courtesy of Addgene).

New Genome Engineering Technique Eases Gene Repair in Human Pluripotent Stem Cells

An RNA-guided, DNA-cleaving interference pathway from bacteria has been adapted for use in eukaryotic cells, greatly facilitating genome editing. More...
29 Aug 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.