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BioResearch

Image: Schematic diagram of an ion channel. 1 - channel domains (typically four per channel), 2 - outer vestibule, 3 - selectivity filter, 4 - diameter of selectivity filter, 5 - phosphorylation site, 6 - cell membrane (Photo courtesy of Wikimedia Commons).

Microsystem Reduces Cost of Developing Ion Channel Drugs

The use of a microsystem that generates ion channels in a cell-free medium is expected to boost development of drugs that target these channels in the treatment of diseases such as cystic fibrosis, myasthenia gravis, and epilepsy.  More...
11 Dec 2013

Tumor Growth Blocked in Mice by Suppressing Antioxidants in Cancer Cells

Superoxide dismutase 1 (SOD1) is overproduced in lung adenocarcinomas and has been implicated as a target for chemotherapy.  More...
11 Dec 2013
Image: The glowing yellow specks in the image show uptake of the nanosponge vaccine by a mouse immune system dendritic cell. The detained alpha-hemolysin toxins were labeled with a fluorescent dye, which glows yellow. The cell membrane was stained red and the nuclei stained blue (Photo courtesy of the University of California, San Diego,  Department of NanoEngineering).

Novel Nanosponge Vaccine Protects Mice from MRSA Toxin

A novel vaccine based on "nanosponges" that sequester toxic, pore-forming toxoids permits presentation of these toxins to immune system defensive cells without danger of damaging them.  More...
10 Dec 2013

Boosting Mitochondrial Function May Nullify Resistance to Radiotherapy

The resistance of some cancers to the cell-destroying effects of radiation therapy may be caused by mitochondrial abnormalities, according to an international team of researchers.   More...
10 Dec 2013
Image: Malaria parasites (labeled with fluorescent protein) in the late stages of development, superimposed on a field of red blood cells. The many nuclei of the parasites\' daughter cells are labeled in blue, and the plasma membranes surrounding the daughter cells are labeled in green. Imidazopyrazine treatment disrupts formation of the membranes around the daughter cells (Photo courtesy of Dr. Marcus C.S. Lee, Columbia University Medical Center).

Imidazopyrazines Kill the Malaria Parasite at Every Stage of Its Life Cycle

An enzyme that is vital to all life stages of several species of malaria parasites has been cited as a tempting target for drug developers.  More...
09 Dec 2013

Global Healthcare’s Three Big Forecasts: mHealth, Cloud Healthcare, and Regulator Environments

A new market research report, based on a 2013 growth survey, identified major areas of eHealth technology and integration with other businesses.   More...
09 Dec 2013
Image: A new technique allows diabetics to control insulin release with an injectable nano-network and portable ultrasound device (Photo courtesy of North Carolina State University).

Ultrasound, Nanoparticles Help Diabetics Avoid the Needle

A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections, instead of using needles to give themselves multiple insulin injections each day.   More...
05 Dec 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.