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BioResearch

Image: The structure of the sirtuin protein Sirt1 (Photo courtesy of Shin-ichiro Imai/Washington University in St. Louis).

Protein Found to Play Key Role in Long Life

The process behind the functioning of a specific protein already believed to play a role in longevity has recently been established to do just that, lengthen lifespan. More...
02 Oct 2013

Human Brain Tumor Cells Eradicated in Lab Mice

Scientists have discovered that treatment with a repurposed US-approved pharmaceutical blocked the growth of, and ultimately left no measurable trace of, brain tumor cells taken from adult human patients. More...
02 Oct 2013

Research Partnership Seeks Compounds to Slow Loss of Motor Neurons in ALS

A research institute is collaborating with a drug discovery company to identify compounds that can prevent or slow down the loss of motor neurons, which is characteristic of the human disease amyotrophic lateral sclerosis. More...
01 Oct 2013
Image: Triple-vacuum-packed Pyrofree vials (Photo courtesy of ATMI, Inc.).

Transatlantic Partners to Produce Pyrogen-Free Containers for the Biopharmaceutical Industry

American and French manufacturers of products for the biopharmaceutical industry are teaming up to produce a line of sterile, pyrogen-free vials and containers. More...
30 Sep 2013
Image: The Intact Modular Filler (IMF) is a fully integrated, automatic filling machine performing all filling activities, including container loading, positioning, filling, and container unloading. The IMF can fill glass or plastic containers of various shapes and sizes (bottles, vials, pouches) with high precision and consistency (Photo courtesy of Medical Instill Technologies).

Partnership to Promote Multiple-Use Filters and Connectors for the Biopharmaceutical Industry

A partnership has been established to promote the utilization of multiple-use sterile filtration and connection devices in the biopharmaceutical industry. More...
30 Sep 2013
Image: Inhibiting DGKi reduces ENaC activity, reversing the effects of cystic fibrosis. In this assay, the green glow dims more in cells with active ENaC (bottom), so the scientists screened for cases where the cells’ glow barely changed (top) (Photo courtesy of Dr. Rainer Pepperkok, European Molecular Biology Laboratory).

siRNA Screen Identifies Potential Cystic Fibrosis Drug Target

A large-scale screen combining high-content live-cell microscopy and small interfering RNAs in human airway epithelial cells from patients with cystic fibrosis has pinpointed a promising target for drug treatment. More...
26 Sep 2013
Image: DNA makes glue programmable because one strand of DNA will stick tightly to a matching partner strand, but only if the two strands have chemical “letters” or nucleotides, that are complementary. Gel bricks coated with matching strands of DNA adhere specifically to each other (Photo courtesy of the Wyss Institute).

Programmable Glue Comprised of “DNA Bricks” Used to Regenerate Damaged Organs, Construct Human Tissues

A team of US scientists has found a way to self-assemble complex structures out of bricks smaller than a grain of salt More...
26 Sep 2013
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.