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BioResearch

Image: An artist's rendition of a Lentivirus expression vehicle (Photo courtesy of AMS Biotechnology ).

MicroRNA Studies to Be Enhanced by a New Line of Anti-miRNA Tools

A novel line of ready-to-use lentiviral expression vehicles provides microRNAs and miRNA inhibitors for use as tools for the study of miRNAs and their role in various disease processes.   More...
13 Feb 2014
Image: The GloMax Discover, an integrated multimode detection plate-reader system (Photo courtesy of the Promega Corporation).

New Microplate Reader Optimized for Fluorescent and Bioluminescent Assays

Biotech and other life science researchers now have available a new microplate reader system that provides superior sensitivity, performance, and flexibility with minimal user intervention.  More...
13 Feb 2014
Image: Shown here is a tumor that metastasized from its original site in the prostate to the lung. Researchers were surprised to find the Myc protein in these tumors and, through further experiments, discovered that simply increasing the amount of Myc in the cell was enough to drive metastasis, suggesting a druggable target for metastatic prostate cancer (Photo courtesy of Cold Spring Harbor Laboratory).

The MYC Oncogene Initiates and Maintains Metastasis in Mouse Prostate Cancer Model

A mouse metastatic prostate cancer model is expected to enable researchers to better investigate the causes of the disease while at the same time test new therapeutics to treat it.  More...
12 Feb 2014
Image: Breast cancer cell. Triple-negative breast cancer is an aggressive disease with few therapeutic options. Patients with such tumors can be treated only with chemotherapy (Photo courtesy of the National Cancer Institute).

Engineered Virus Designed to Fight Triple-Negative Breast Cancer

Scientists have found a possible cure for one of the most deadly, aggressive, and least treatable forms of breast cancer called triple-negative breast cancer.   More...
11 Feb 2014
Image: The Zucker diabetic fatty (ZDF) rat compared to a normal laboratory rat (Photo courtesy of medic, Japan).

Experimental Drug Reduces Brain Inflammation in Diabetic Rat Model

A recent paper reported that peptides that mimic the activity of thioredoxin were able to inhibit the development of inflammation in the brains of Zucker diabetic fatty rats.  More...
11 Feb 2014
Image: Researchers have created embryonic-like stem cells with the ability to develop into any of the dozens of highly specialized cells of the body, ranging from cardiac-muscle cells to the nerve cells of the brain and spinal cord (Photo courtesy of Brigham and Women’s Hospital / RIKEN Center for Developmental Biology).

Embryonic Stem Cells Created Without Embryo

US and Japanese researchers have demonstrated that any mature adult cell, known as a somatic cell, has the potential to change into the equivalent of an embryonic stem cell.  More...
11 Feb 2014
Image: Elevation of RIPK3 in nuclei of neurons (red; arrows) from neuronopathic Gaucher's disease mice (Photo courtesy of Dr. Anthony Futerman, Weizmann Institute of Science).

Enzyme Deficiency Improves Clinical Picture in Mouse Model of Gaucher's Disease

Blocking the activity of a specific enzyme reversed the clinical symptoms of Gaucher's disease in a mouse model of this hereditary lipid storage disease. More...
10 Feb 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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