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BioResearch

Biotechnology Merger to Spur Development of a Gene Therapy Approach for Treatment of Congestive Heart Failure

Rapid improvement in the treatment of congestive heart failure is expected following the acquisition of InoCard, a German early-stage biotechnology company by uniQure, a Dutch leader in the field of gene therapy.  More...
24 Aug 2014
Image: The DrySyn MULTI converts any standard hotplate stirrer into a high performance reaction block (Photo courtesy of Asynt).

New Reaction Vessel Heating System Is Cleaner and Safer

Biotech and other life science researchers can create a safer, cleaner, and more efficient working environment in their laboratories by switching from oil bath-based heating of reaction vessels to a new high performance reaction block that can be used with any hotplate stirrer.  More...
20 Aug 2014
Image: The presence of p45 (green staining) and p75 (red staining) indicates that motor neurons increase both p45 and p75 expression after sciatic nerve injury in an animal (Photo courtesy of the Salk Institute for Biological Studies).

Blocking Nerve Growth Factor Receptor Enables Human Nervous System Regeneration

The mystery of why the human nervous system is unable to regenerate may have been at least partially solved with the identification of a protein called p75 that seems to block the repair of damaged nerve cells.   More...
20 Aug 2014
Image: In mice whose brain tumor cells (in green) could not make galectin-1, the body’s immune system was able to recognize and attack the cells, causing them to die. In this microscope image, the orange areas show where tumor cells had died in just the first three days after the tumor was implanted in the brain. Six days later, the tumor had been eradicated (Photo courtesy of the University of Michigan).

Surface Protein Protects Brain Tumor Cells from Immune Attack

Malignant glioma brain tumor cells suppress the natural killer cell immune response by over expressing the surface protein galectin-1, and suppression of this protein renders the tumor cells susceptible to destruction by the immune system.   More...
19 Aug 2014
Image: Neurons (greenish yellow) attach to silk-based scaffold (blue) creating functional networks throughout the scaffold pores (dark areas) (Photo courtesy of Tufts University).

Functional 3D Brain-Like Tissue Model Bioengineered

Researchers reported on the development of the first complex, 3D model comprised of brain-like cortical tissue that displays biochemical and electrophysiologic responses, and can function in the laboratory for months.   More...
19 Aug 2014
Image: The European Commission has approved the use of Avastin combined with chemotherapy as a treatment for women with recurrent ovarian cancer (Photo courtesy of Genentech).

Drug for Treatment of Platinum Resistant Recurrent Ovarian Cancer Approved for Use in Europe

For the first time in more than 15 years the European Commission has approved a new therapeutic option for the most difficult to treat form of ovarian cancer.  More...
18 Aug 2014
Image: Extension of human axons into host adult rat white matter and gray matter three months after spinal cord injury and transplantation of human induced pluripotent stem cell-derived neurons. Green fluorescent protein identifies human graft-derived axons, myelin (red) indicates host rat spinal cord white matter and blue marks host rat gray matter (Photo courtesy of UCSD – University of California, San Diego School of Medicine).

Grafted Human Stem Cells Experience Drastic Growth in Spinal Cords of Rats

Scientists have reported that neurons derived from human induced pluripotent stem cells and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals’ central nervous system.  More...
18 Aug 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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