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BioResearch

Image: Dysregulation of the protein Chi3l1 allows melanoma (black specks) to spread to the lungs of mice. Chi3l1 was relatively unchecked in the lung on the right, compared to the lung on the left, which had much less spread of the cancer (Photo courtesy of Brown University).

Novel Molecular Pathway Controls Metastasis in Mouse Melanoma Model

Cancer researchers have found that the protein Chi3l1 stimulates formation of metastases in a mouse model under the regulatory influence of the protein semaphorin 7a and its receptors.  More...
05 Jan 2015
Image: A membrane protein called cysZ, imaged in three dimensions with Phenix software using data that could not previously be analyzed (Photo courtesy of the Los Alamos [US] National Laboratory).

New Software Uses X-Ray Diffraction to Generate 3-D Images of Molecular Machines

Scientists are making it simpler for pharmaceutical companies and researchers to visualize the precise inner processes of molecular machines.  More...
05 Jan 2015
Image: Three-dimensional molecular space-fill model of resveratrol (Photo courtesy of Wikimedia Commons).

Low Doses of Resveratrol Activate Stress-lowering Molecular Pathway

A molecular mechanism has been identified that explains how the wine and grape product resveratrol modulates the inflammatory response by interacting with the enzyme tyrosyl transfer-RNA synthetase.  More...
04 Jan 2015

United Kingdom to Build a New Cell and Gene Therapy Manufacturing Center

The United Kingdom Cell Therapy Catapult plans to build the new GBP 55-million Cell Therapy manufacturing center in the Stevenage Bioscience Catalyst campus.   More...
04 Jan 2015
Image: Washington University engineers have developed the world’s fastest receive-only 2-D camera that can capture events up to 100 billion frames per second (Photo courtesy of Washington University).

Compressed Ultrafast Photography Designed to Aid Scientific Research

A group of biomedical engineers has developed the world’s fastest receive-only, two-dimensional camera, a device that can capture actions up to 100 billion frames per second. That is remarkably more rapid than any current receive-only ultrafast imaging techniques, which are limited by on-chip storage and electronic readout speed to operations of approximately 10 million frames per second.  More...
31 Dec 2014
Image: Imaging and sizing of single DNA molecules on a mobile-phone (Photo courtesy of the Ozcan Lab at UCLA - the University of California, Los Angeles).

Hardware Attachment and Dedicated App Turn Smartphone into a Fluorescence Microscope

A hardware attachment with an associated application turns a smartphone into a sensitive microscope capable of determining the length of individual DNA molecules.  More...
30 Dec 2014
Image: Dermal fibroblasts are directly reprogrammed to pigmented melanocytes by three transcription factors (SOX10, MITF, and PAX3) (Photo courtesy of the University of Pennsylvania).

Direct Reprogramming of Fibroblasts into Melanocytes Avoids Cancer Threat

A team of cell biologists has successfully induced fibroblasts to convert to functional melanocytes without going through a preliminary pluripotent stage.  More...
29 Dec 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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