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BioResearch

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Environmentally Friendly Ultra-Low Temperature Freezer Requires Less Energy While Generating Less Noise

A new line of ultra-low temperature freezers was designed for both increased cryopreservation capability and improved performance in the laboratory environment.  More...
22 Apr 2015
Image: Low-temperature plasmas are formed in a chamber like the one shown in the photo by applying a high electric field across a gas at atmospheric pressure and room temperature (Photo courtesy of the University of York).

Low-Temperature Plasma Treatment Kills Prostate Cancer Cells

By combining physics and biology a team of British cancer researchers has shown that low-temperature plasma treatment kills prostate cancer cells in culture and may warrant development into a therapeutic tool to replace radiation and photodynamic methods.  More...
22 Apr 2015
Image: Senior author Dr. Aaron Ciechanover shared the 2004 Nobel Prize in chemistry for his work on the ubiquitin system (Photo courtesy of the Technion-Israel Institute of Technology).

Suppression of Tumor Growth Linked to Actions of the Ubiquitin System

Cancer researchers working with mouse xenograft and human cancer cell cultures have identified components of the ubiquitin system that are linked to certain cellular processes, which act to suppress malignant growth and protect healthy tissues.  More...
21 Apr 2015
Image: Two adjacent sections of a mouse breast tumor. The tissue at left was stained so that normal blood vessels can be seen (black arrow); extending from these vessels are blood filled channels (green arrows). On the right, the tissue was stained for a fluorescent protein expressed by the tumor cells. Here it is seen that blood-filled channels were actually formed by tumor cells in a process known as vascular mimicry (Photo courtesy of Cold Spring Harbor Laboratory).

Two Secreted Proteins Prepare Breast Cancer Cells for Metastasis

Two genes that code for secreted proteins have been found to be responsible for the development of vascular mimicry—imitation blood vessels—by tumor cells and for preparing some tumor cell clones to spread away from the site of the primary tumor.  More...
21 Apr 2015
Image: Molecular model of CARDS toxin, which was first described in 2006 (Photo courtesy of the University of Texas Health Science Center at San Antonio).

Crystal Structure of CARDS Toxin Expected to Advance Respiratory Disease Treatment

A recent paper described the molecular structure of Mycoplasma pneumoniae's Community Acquired Respiratory Distress Syndrome toxin and explained how knowing this structure may lead to advances in the prevention and treatment of diseases caused by this respiratory pathogen.  More...
20 Apr 2015
Image: Electrophoretic data confirmed disruption of mitosis in cells lacking GR (Photo courtesy of the University of Manchester).

Glucocorticoid Receptor Suppresses Tumor Formation by Ensuring Accurate Chromosome Segregation During Mitosis

A team of British molecular biologists has defined the mechanism by which glucocorticoid receptor regulates the process of mitosis to prevent errors in cell division that could lead to tumor formation.  More...
20 Apr 2015
Image: A protein — shown in red, white, and blue — typically coats the genome of the Ebolavirus, providing protection from enzymes that can destroy the virus’s genetic material. This protein coat is removed to allow the virus to replicate its genome in infected cells. Interfering with the removal and the return of the protein coat to the viral genome can kill the Ebola virus, a discovery that opens the door to more effective treatments (Photo courtesy of Washington University School of Medicine).

Ebolavirus Nucleoprotein Suggested as Possible Drug Target

A team of molecular virologists has isolated and characterized a peptide from Ebolavirus that is critical to the pathogen's ability to reproduce inside infected cells.  More...
19 Apr 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.