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BioResearch

Image: The automated, benchtop Irys instrument enables the genomic researcher to acquire high-resolution, multi-color images and conduct single-molecule analysis of long DNA molecules (Photo courtesy of BioNano Genomics).

Hybrid Gene Mapping Approach Yields Reference Quality Results

A team of genomics researchers from the USA and Europe have developed a new approach for describing nearly complete genomes by combining high-throughput DNA sequencing with genome mapping techniques.  More...
15 Jul 2015
Image: Without angiogenesis a tumor cannot grow beyond a limited size (Photo courtesy of Cancer Research UK/Wikimedia Commons).

Findings Explain How Tumors Guide New Blood Vessel Formation

Tumors must generate new blood vessels in order to grow, and a recent paper described a novel Rho-family GTPase activation cascade that was required for the generation of the endothelial cell filopodial protrusions that are necessary for the tubule remodeling that forms the lumen through which the blood will flow. More...
15 Jul 2015
Image: Micrograph of pancreatic ductal adenocarcinoma (the most common type of pancreatic cancer) (Photo courtesy of Wikimedia Commons).

Restoration of MicroRNA Activity Slows Progression of Pancreatic Cancer

Cancer researchers have linked progression of pancreatic cancer to the loss of microRNA-29 activity.  More...
15 Jul 2015

Highly Elastic Protein Gel Encourages Wound Healing

A new study describes a protein-based gel that mimics many of the properties of elastic tissue—such as skin and blood vessels—when exposed to light.  More...
15 Jul 2015
Image: CRISPR-Cas9 gene-editing complex from Streptococcus pyogenes (Photo courtesy of Harvard Medical School).

Modifications Should Increase the Usefulness of CRISPR-Cas9 Gene Editing

A recent paper described a procedure to modify the CRISPR-Cas9 class of DNA editing nucleases to give them a wider range of usefulness and simultaneously reduce the number of off-target mutations that could be generated.  More...
14 Jul 2015
Image: Cranberries grown and harvested in Massachusetts (USA). Cranberry juice was found to lower risk of developing cardiovascular disease (Photo courtesy of Wikimedia Commons).

Low-Calorie Cranberry Juice Shown to Lower Cardiovascular Disease Risk

Supplementing the diet with low-calorie cranberry juice reduces the chances of developing cardiovascular disease by lowering several risk factors including circulating triglycerides, C-reactive protein, glucose, and diastolic blood pressure.  More...
14 Jul 2015
Image: Structure of the ADAM17 protein (Photo courtesy of Wikimedia Commons).

Cancer Development: A Molecular Pathway Controls ErbB Signaling via PACS-2 Regulation of Recycling of the Metalloproteinase ADAM17

Some types of cancer are triggered by excessive ErbB signaling, and researchers have now discovered a molecular pathway that regulates this process.  More...
13 Jul 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.