BioResearch
Experimental Small-Molecule Anticancer Drug Blocks RAS-binding Domains
The experimental small-molecule anticancer drug rigosertib was shown to block tumor growth by acting as an RAS-mimetic and interacting with the RAS binding domains of RAF kinases, resulting in their inability to bind to RAS, which inhibited the RAS-RAF-MEK pathway. More...04 May 2016
Cardiac Researchers Use Stem Cells to Generate Functional Heart Muscle 
Stem cell researchers have developed a new technique to form micro-scale arrays of engineered heart muscle (EHM) from fewer than 10,000 starter cells without requirement for adherence features or extracellular matrix (ECM). More...
03 May 2016
Cells Loaded with Prodrug-Containing Microparticles Selectively Destroy Prostate Cancer Tumors
A novel approach to treating metastatic prostate cancer with minimal adverse side effects is based on cellular transport of a harmless prodrug that is activated and becomes toxic only in the vicinity of the tumor microenvironment. More...02 May 2016
Stem Cells Derived from Older Individuals May Carry Unsafe Mitochondrial DNA Mutations
Induced pluripotent stem cells (iPSCs) derived from the skin fibroblasts of older individuals have a likelihood of harboring mitochondrial DNA mutations, which may render them unfit for clinical applications. More...29 Apr 2016
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In Other News
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Defective Genome Instability Suppressing Genes May Cause Some Types of Cancer
X-ray Crystallography Study May Lead to New Drugs to Block Cancer Metastasis
Cardiomyopathy Linked to Faulty Regulation of Heart Protein Succinylation
Huge Modifiable Biomedical Database to Be Available on the Wikidata Site
A Host Protein Interferes with the Immune System's Ability to Deal with DNA Viruses
Next-generation sCMOS Microscope Cameras Offer High Resolution Live Cell Imaging
Growth and Spread of Breast Cancer Linked to Tumor Cells' Expression of a Cartilage Protein
Study Identifies Mechanism Underlying a Form of Sensory Nerve Damage
Pathway Implicated in Development of Eosinophilic Esophagitis
Mouse Model Study Supports Sexual Transmission of Zikavirus Infection
Ganglioside Probes Enable Tracking of Membrane Lipid Rafts in Living Cells
Enzyme-Loaded Magnetic Nanoparticles Suitable for Therapeutic and Industrial Applications
Carbon Nanotube-Based Device Efficiently Transports Nucleic Acids into Cell Cultures
Supply of Lipid Precursors Modulates Growth of Breast Cancer Cells
DNA Synthesis Specialists Acquire Advanced Software Design Capabilities
Cholesterol Analogs Block Growth of Tuberculosis Bacteria
Novel Nanogel Drug Delivery System to Undergo Preliminary Clinical Trials
Drug Company Buyout to Boost Development of Liver Disease Drugs
Cryo-EM Techniques to Be Exploited by UK-Based Research Consortium
Review Promotes Use of Clinical Exome Sequencing for Diagnosis of Neurological Diseases
Smart Nanoparticle Drug Delivery System Avoids Tumor-Protecting Obstacles
Indirect Inhibition of Overexpressed Androgen Receptor Activity Halts Growth of Castration-Resistant Prostate Cancer
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.