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BioResearch

Image: A structural model of the RUNX3 protein (Photo courtesy of Wikimedia Commons).

Phosphorylation Turns a Tumor Suppressor into a Promoter of Cancer Development

Cancer researchers have determined the molecular mechanism by which a modification to the protein encoded by the RUNX3 gene turns a tumor suppressor into a promoter of cancer development and progression. More...
03 Aug 2016
Image: A photomicrograph (200X) showing McCoy cell monolayers with Chlamydia trachomatis inclusion bodies (Photo courtesy of the CDC).

Prototype Vaccine Protects Against Multiple Chlamydia Strains

A prototype vaccine to protect against Chlamydia trachomatis infection gave promising results when tested in vitro and in a mouse model system. More...
03 Aug 2016
Image: Multiple bacilli (rod-shaped bacteria, here shown as black and bean-shaped) shown between white blood cells in urinary microscopy. These changes are indicative of a urinary tract infection (Photo courtesy of Wikimedia Commons).

Bladder Cells Use Exocytosis to Fight Urinary Tract Infections

A team of molecular microbiologists has identified a method used by the cells lining the bladder to protect themselves against urinary tract pathogens by packaging bacteria into vesicles that are expelled from the cytoplasm. More...
02 Aug 2016
Image: The diagram shows the difference between regular and plasmonic gratings in terms of fluorescent intensity (Photo courtesy of Dr. Shubhra Gangopadhyay, University of Missouri).

Plasmonic Resonance Optical Microscope Has Capability of an Electron Microscope

A novel, relatively low cost microscopy technique enables an optical fluorescent microscope to display images with the resolution of an electron microscope. More...
02 Aug 2016
Image: Some compounds in cranberries act to prevent urinary tract infections by keeping infectious bacteria from adhering to the lining of the urinary tract (Photo courtesy of the Worcester Polytechnic Institute).

Several Cranberry Extracts Act to Prevent Infection by Reducing Bacterial Adhesion

Various chemical compounds have been isolated from cranberries and analyzed to determine their ability to prevent infection by reducing or eliminating adhesion of bacteria to biological surfaces. More...
02 Aug 2016
Image: A scanning electron micrograph (SEM) of a liver cancer cell (Photo courtesy of SPL).

Novel Treatment Uses Bacteria Engineered to Delivery Pulses of Anti-Cancer Drugs

A novel method for treating liver tumors is based on genetically engineered bacteria that respond to population pressure by lysing and releasing pulses of anti-cancer drugs. More...
01 Aug 2016
Image: Primary hippocampal neurons from mice expressing G2019S-LRRK2. The neurons were treated with alpha-synuclein fibrils, and 18 days later immunofluorescence was performed. The magenta shows phospho-alpha-synuclein inclusions in the cell bodies and throughout the axons, which are visualized as green (Photo courtesy of the University of Alabama).

Inhibitors of a Mutant Kinase May Be Potential Treatment for Parkinson's Disease

A potential therapeutic approach for treatment of Parkinson's disease is based on drugs that block the activity of a mutated version of the enzyme LRRK2 (Leucine-rich repeat kinase 2). More...
01 Aug 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.