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BioResearch

Image: Multipotent stem cells, responsible for the development of the prostate (Photo courtesy of Dr. C. Blanpain, Université libre de Bruxelles).

Pair of Enhanced Techniques Developed for Stem Cell Lineage Tracing

European cell biologists have developed a pair of methods for the precise assessment of the multipotent or unipotent fate of stem cells. More...
21 Jun 2016
Image: When packaged inside tobacco mosaic virus nanoparticles, phenanthriplatin is delivered to tumors, where it was shown to be more effective in vivo than an approved platin (Photo courtesy of Case Western Reserve University).

Tobacco Mosaic Virus Nanoparticle Delivery System Increases Potency of Experimental Anticancer Drug

A candidate anticancer drug was found to be considerably more potent than standard treatments and this potency was further increased in a mouse model when the drug was delivered by a tobacco mosaic virus (TMV)-based transport system. More...
20 Jun 2016
Image: Molecular model of a hydrogel consisting of custom peptide fibers with spaces - \"missing teeth\" - that can trap and deliver hydrophobic small-molecule drugs (Photo courtesy of I-Che Li, Rice University).

Custom Designed Peptides Transport Hydrophobic Drug Compounds

A bioengineering team has designed a novel class of drug-delivery peptides that coalesce into a hydrogel capable of transporting hydrophobic compounds within the hydrophobic cores of the peptide nanofibers. More...
20 Jun 2016
Image: Incorrectly folded serpin proteins can cause a variety of diseases. Danish researchers have found a solution for preventing this misfolding (Photo courtesy of Jan K. Jensen, Aarhus University).

Aptamer Prevents Serpin Misfolding without Damaging Protease Inhibition

A team of Danish molecular biologists has developed an aptamer that blocks misfolding of mutant serpin protease inhibitors while maintaining the protein's inhibitory function. More...
20 Jun 2016

Acquisition to Boost Development of Drugs for Neurogenic Conditions

According to a recent announcement, a privately held biotechnology/drug development company is to be acquired by one of the major pharmaceutical manufacturers. More...
20 Jun 2016
Image: A micrograph of hepatocellular carcinoma from a liver biopsy (Photo courtesy of Wikimedia Commons).

Prospective Study of Liver Cancer Risk Shows Value of Circulating microRNAs

A prospective study conducted on a group of individuals who had been infected with hepatitis B virus (HBV) has shown that a panel of 15 microRNAs (miRNAs) could predict high or low risk of developing liver cancer (hepatocellular carcinoma). More...
16 Jun 2016
Image: The new active ingredient consists of DARPins (red and orange) that bend the HER2 receptors (blue) so no more growth signal is transmitted into the cell interior (below the cell membrane in yellow) (Photo courtesy of the University of Zurich).

Novel Class of Drugs Selectively Kills HER2-positive Breast Cancer Cells

A team of Swiss drug developers has designed a novel drug that cures breast cancer by completely blocking the activity of the surface receptor HER2 (human epidermal growth factor receptor 2). More...
16 Jun 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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