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BioResearch

Image: A molecular model showing the experimental antibody drug ZMapp binding to the Ebola virus, here targeting the virus\'s GP protein (Photo courtesy of Dr. Andrew Ward and Dr. Jesper Pallesen, Scripps Research Institute).

High-Resolution Cryo-EM Images Increase Understanding of Anti-Ebola Drug

High-resolution cryo-electron microscopy images have revealed more precise information as to how the experimental drug ZMapp binds to the Ebola virus and provide insights into how the drug prevents growth of the pathogen. More...
18 Aug 2016
Image: A transmission electron microgragh (TEM) of Deinococcus radiodurans (Photo courtesy of Dr. Michael Daly, Uniformed Services University of the Health Sciences).

Synthetic Antioxidant Peptide Protects Mice from Lethal Levels of Radiation

An antioxidant peptide compound that mimics those produced by the bacterium Deinococcus radiodurans was found to effectively protect cell cultures and mice exposed to lethal levels of gamma radiation. More...
18 Aug 2016
Image: The micrograph shows cross-sections of healthy nerve axons with a thick layer of myelin, the insulation that speeds the propagation of electrical signals through the nervous system\'s wiring. When properly folded, prion proteins play a vital role in maintaining this insulating layer of myelin (Photo courtesy of Amit Mogha, Washington University School of Medicine).

Normal Prion Protein Maintains Myelin Integrity in Nervous System

Researchers studying chronic diseases of the brain have determined the function and mode of operation of the cellular prion protein PrPC, which in its cytotoxic form underlies prion diseases such as spongiform encephalopathy (mad cow disease) and its human counterpart, variant Creutzfeldt-Jakob disease. More...
17 Aug 2016
Image: Trypanosoma sp. parasites in blood smear from a patient with African trypanosomiasis (Photo courtesy of the CDC).

Experimental Drug May Be Universal Cure for Kinetoplastid-Based Diseases

An experimental drug that targets the kinetoplast proteasome found in several types of protozoan parasites shows potential for development into a universal treatment for these pathogenic microorganisms. More...
17 Aug 2016
Image: A molecular model of lectin-type oxidized LDL receptor 1 (Lox-1) (Photo courtesy of Wikimedia Commons).

LDL Receptor Expression Differentiates Myeloid-Derived Cells from Neutrophils

Cancer researchers have identified a surface protein marker on myeloid-derived suppressor cells (MDSCs) that differentiates them from normal neutrophils and may be a potential therapeutic target. More...
17 Aug 2016
Image: The chemical structure of the probe, and the possible probe-dsRNA triplex structure (Photo courtesy of Tohoku University).

Japanese Scientists Describe Powerful Fluorescent Probe for Studying RNA

A team of Japanese biochemists has described the development of a powerful new fluorescent probe for studying the structure and function of double stranded RNA (dsRNA). More...
16 Aug 2016
Image: The experiments were carried out with nanoparticles of different sizes and structures. The first two of the series consisted of solid gold and the last consisted of a core of glass with a surface of gold. The beads were illuminated with near infrared light with wavelengths of 807 nanometers and 1064 nanometers. The most effective nanoparticle was the gold-plated glass bead (Photo courtesy of Kamilla Nørregaard, University of Copenhagen).

Laser-Heated Plasmonic Nanoparticles Safely Cause Localized Tumor Destruction

Cancer therapy based on plasmonic nanoparticles that homed to tumors, warmed on exposure to laser irradiation, and then selectively killed the cancer cells was optimized and shown to be effective in a mouse xenograft model. More...
16 Aug 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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