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BioResearch

Prion Proteins Form Stable Beta-Sheet Structures

Researchers studying how prion particles interact to form long threads of amyloid fibrils have found that in water the mouse PrP106-126 protein fragment assumes a stable structure of parallel beta-sheets that are tightly packed against each other. More...
23 Dec 2003

Peptide Linked with Paclitaxel Destroys Tumors

A tumor-specific peptide linked with the established anticancer agent paclitaxel is the basis for a new highly specific anticancer therapeutic. More...
19 Dec 2003

Avanir Licenses Antibody to Peregrine

An antibody produced for a cancer target as the result of an agreement between Avanir Pharmaceuticals and Peregrine Pharmaceuticals, Inc. has now been licensed to Peregrine by Avanir. More...
19 Dec 2003

Human Antibody Kills Cancer Cells in Mice

A human antibody binds to a unique site on CD20 target cells and appears to stop growth of B-cell tumors in immuno-compromised mice far more effectively than either placebo or a marketed treatment called rituximab. More...
19 Dec 2003

Molecule Shows Promise Against Atherothrombosis

Preclinical results of a molecule designed to combat atherothrombotic disease show that in treated mice, cholesterol levels dropped immediately, atheroma plaque showed signs of regression, and weight gain slowed. More...
17 Dec 2003

Toxicity Assays for Drug Development

A platform of toxicity assays is a colony-forming based system that measures the proliferation of primitive hematopoietic cells in response to stimulators or inhibitory compounds. More...
17 Dec 2003

CART Protein May Neutralize Cocaine

A recent study into the metabolism of cocaine and other psychostimulant drugs found that a CART (cocaine-amphetamine regulated transcript) peptide reduced some of the effects of cocaine when it was injected into the locomotor area of the brain prior to the administration of the drug. More...
17 Dec 2003
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.