BioResearch

Zebra Fish Model Yields Clues to Neuroblastoma Growth
A genome-wide association study (GWAS) conducted in a zebra fish model system identified LMO1, which encodes a LIM-domain-only transcriptional cofactor, as a neuroblastoma susceptibility gene that functions as an oncogene in high-risk neuroblastoma. More...15 Sep 2017

Mycobacteria Use Voltage-Dependent Channels to Prevent Destruction
A team of molecular microbiologists unraveled the mechanism whereby the pathogenic bacterium Mycobacterium avium modifies the environment inside the macrophage phagosome and transforms it from a killing site to place for growth and reproduction. More...14 Sep 2017

Nanoparticle Reagent Simplifies Gene Expression Programming
Novel nanoparticle carriers were used to deliver mRNA directly to specific cell types (T-cells of the immune system and blood stem cells) in order to induce short-term changes in gene expression that could be harnessed to treat diseases ranging from cancer to diabetes. More...13 Sep 2017

Depressing Stress Signaling Increases Immune Activity
Cancer researchers evaluating the immune status of the tumor microenvironment found that CD8+ T-cell frequency and functional orientation were regulated by beta-2-adrenergic receptor (beta-AR) signaling and suggested using clinically available beta-blockers in patients to improve responses to immunotherapy. More...12 Sep 2017


Scandinavian Researchers Discover Potential Arthritis Treatment
The natural polysaccharide alginate and particularly its sulfated derivatives have potent anti-oxidant, anti-inflammatory, and anti-immunogenic properties, which indicate that it may be a promising biomaterial to be explored for treatment of arthritis. More...06 Sep 2017

In Other News
Genetic Variant Links Typhoid Susceptibility to Cholesterol Level
Immunotherapy Slows Tumor Growth in Prostate Cancer Model
Novel Antimicrobial Role of Intracellular Organelle
X-ray Study Explains How Takinib Inhibits TNF-alpha
Combined Approach Cures Bladder Cancer in Model
Stem Cell Therapy Restores Youthful Heart Performance
Study Details Interaction between Galectin-1 and Carbohydrate Ligands
Molecular Manipulation Induces Skin Cells to Produce Hair
Progress Reported in Development of Gene Editing Tool
Gene Editing Used to Repair Mutations in Embryos
Interaction of Cell Surface Glycoproteins Drives Tumor Metastasis
Folate-Bound MicroRNAs Slow Tumor Progression in Models
Normal Skin Resists and Rejects Cancerous Growth
Novel In Vitro Method May Revolutionize Antibody Production
Imaging Technique Reveals 3D Structure of DNA and Chromatin
Study Shows Curcumin Kills Childhood Neuroblastoma Cells
Gene Editing Prevents Onset of Retinal Angiogenesis
Study Highlights Ethnic Diversity of Lupus-Linked Genes
Biodegradable Flu Booster Enhances Vaccine Effectiveness
Horseradish Complex Increases Sensitivity of Immunochemical Assays
RNA Library to Enhance CRISPR/Cas9 Gene Editing
Tomatoes in Diet Protect Mice from Skin Cancer
Fisetin Effectively Prevents Age-Related Dementias in Model
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.








