BioResearch
Model Demonstrates Potential for Long-Term Gene Silencing
An adeno-associated viral (AAV) vector was used to deliver a modified version of the CRISPR/Cas9 gene-editing tool to liver cells in a mouse model, which resulted in suppression of the serum enzyme Pcsk9 and reduction of cholesterol levels. More...08 May 2018
Protein Droplets Stimulate Neurodegenerative Fibril Clumping
A team of neurodegenerative disease researchers has identified a molecular mechanism that prevents or reverses the formation of insoluble protein aggregates that characterize several brain disorders, including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). More...03 May 2018
![Image: Recovery of the injured heart muscle after four weeks of treatment with extracellular vesicles. Immunostains: wheat germ agglutinin (red), troponin (green), and DAPI [(4\',6-diamidino-2-phenylindole)] (blue) (Photo courtesy of Dr. Gordana Vunjak-Novakovic, Columbia University School of Engineering and Applied Science).](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2018-05-02/GMS-082.jpg "Image: Recovery of the injured heart muscle after four weeks of treatment with extracellular vesicles. Immunostains: wheat germ agglutinin (red), troponin (green), and DAPI [(4\',6-diamidino-2-phenylindole)] (blue) (Photo courtesy of Dr. Gordana Vunjak-Novakovic, Columbia University School of Engineering and Applied Science).")
![Image: An illustration of blood vessels including artery, arteriole, capillaries, vein and venule (Photo courtesy of the [U.S.] National Cancer Institute).](https://globetechcdn.com/mobile_labmedica/images/stories/articles/article_images/2018-05-01/GMS-081.jpg "Image: An illustration of blood vessels including artery, arteriole, capillaries, vein and venule (Photo courtesy of the [U.S.] National Cancer Institute).")
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Vaccine Cures and Protects against West Nile Virus
Finnish Study Describes Activators of SIRT6 Gene
Nano-Imaging Reveals Links to Regulation of Bone Mineralization
Compound Demonstrates Potential as Broad-Spectrum Antiviral Drug
Stroke Genetics Study Triples Number of Known Risk Loci
Critical Brain Cell Repair Gene Identified in Study
Antibody Clears Amyloid Plaques in Mouse Model
Role of RNA Methylation Defined in Drug Resistance by Leukemia Cells
Less Toxic Drugs May Replace Current Chemotherapeutic Agents
Pecan-Enriched Diet Protects against CV Disease and Diabetes
Review Article Summarizes Progress Towards Drug Development
Nanospear Technology Developed for Directed Gene Therapy
Innovations Increase Sensitivity of CTC Detection
Novel Gene-Editing Tool Specifically Modifies RNA
Virtual Model Set to Boost Drug Development Efforts
Genetic Link Found for Physical and Psychological Disorders
Hydrogel Developed for Controlled Release of Immunotherapeutic Drugs
Microscopy Technique Monitors Biomarkers of Subcellular Alterations
Biomimetic Nanoparticles Prove Effective for Biotherapeutic Drug Transport
BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.