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Unlimited Amount of DNA from Few Cells

By Biotechdaily staff writers
Posted on 19 Nov 2002
New products and services can extract and amplify an unlimited amount of high quality DNA from just a few cells.

Known as REPLI-g Whole Genome Amplification, the products and services are based on technology called Multiple Displacement Amplification licensed from Yale University (New Haven, CT, USA) by Molecular Staging, Inc. (MSI, also in New Haven). This technology can extract and amplify the entire human genome many thousand-fold with unmatched accuracy in a few simple steps, says MSI.

Whole Genome Amplification works on a variety of samples, including extracted gDNA, blood, buccal swabs, buffy coats, and needle aspirates. Scientists have the option of sending samples to MSI or, alternatively, purchasing a range of easy-to-use REPLI-g Whole Genome Amplification kits from MSI.

"As more single nucleotide polymorphisms (SNP) assays and new biomarkers become available, scientists will want more and more DNA to satisfy the demand for all of the tests they want to do,” said Dr. Stephen Kingsmor, CEO of MSI. "The technology will be enormously valuable for clinical researchers, particularly those with banked samples for whom the option of returning to a patient for an additional blood draw is either prohibitively expensive or impossible.”




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