Human ORF Clones Available to Scientists
By Biotechdaily staff writers
Posted on 09 Jul 2002
More than 8,000 human open reading frame (ORF) clones from full-length genes have been released to the scientific community, derived from a collection of highly curated and verified human full-length cDNAs.Posted on 09 Jul 2002
The entire collection, called ORFexpress, has been cloned into a vector system compatible with the Gateway technology of Invitrogen Corp. This allows rapid and simple transfer of the coding ORFs into a whole suite of Gateway destination vectors, as well as transfer of ORFs into other expression vectors via restriction and ligation--significantly facilitating the expression and functional analyses of target proteins and shortening drug discovery time. The collection was assembled by GeneCopoeia, Inc. (Frederick, MD, USA). The clones are available on the company's website for the internal research purposes of scientists.
"The release of these clones to the scientific community makes finding a high quality gene in a ready-to-use format as easy as clicking your mouse,” said Shuwei Yang, president of GeneCopoeia. "We are continuing to add new clones every week and will also begin work on other model organisms such as mouse and other pathogenic organisms.”
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