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Brain Protein May Be Early Indicator of Alzheimer’s Disease

By LabMedica International staff writers
Posted on 08 Feb 2012
Recent research has shown that specific proteins found in exosomes may be indicators of advanced Alzheimer’s disease (AD).

The scientists discovered that exosomes containing tau and other proteins are an indicator of AD. Exosomes can be found in the cerebral spinal column and examined through a spinal tap. High levels of tau found in the exosome are an indicator of advanced stages of AD.

The researchers from MassBay Community College (Wellesley Hills, MA, USA) successfully collaborated with biologic science counterparts from University of Massachusetts (UM)-Lowell (MA, USA) and Boston University (MA, USA) on experiments related to early detection of AD. The research was performed in MassBay’s biotechnology and environmental science labs.

According to Dr. Sudad Saman, an adjunct professor of STEM at MassBay, and researcher and author of the article, stated, “Often Alzheimer’s disease is detected in patients in its later stages, when the disease has become more apparent to loved ones. By discovering Alzheimer’s in patients earlier, they can start taking medications, even five years earlier can be beneficial to extending the life of the individual as well as delaying the degenerating effects of the disease.”

“This is extraordinary work being done here at MassBay,” said President John O'Donnell. “MassBay has long benefitted from world-class biotechnology and environmental science programs, and our elite professors continue to make important contributions to the world of science.”

“The result of our work may become revolutionary in diagnosing Alzheimer’s disease in its early onset,” concluded Dr. Sudad Saman. “We believe our discovery is quite significant.”

Related Links:

Boston University
MassBay Community College
University of Massachusetts-Lowell



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