Newly Identified Protein Biomarkers in Blood Predict Sudden Cardiac Arrest Before it Strikes
By LabMedica International staff writers Posted on 27 Jan 2023 |
Sudden cardiac arrest, or the sudden loss of heartbeat, is a life-threatening heart condition and often fatal. Despite providing an organized emergency medical response, less than 10% of individuals having a cardiac arrest will survive. Hence, there is a need for risk determination, early prediction, and improved primary prevention of sudden cardiac arrest. Now, researchers have identified a panel of novel blood biomarkers specifically associated with sudden cardiac arrest. These biomarkers have the potential to enhance the clinical prediction of sudden cardiac arrest.
In a collaborative study, investigators at Cedars-Sinai (Los Angeles, CA, USA) analyzed a number of blood biomarkers obtained from survivors of sudden cardiac arrest. They compared the results from one cohort of people without coronary artery disease and one cohort with the disease. The researchers identified 26 protein biomarkers associated with sudden cardiac arrest that could improve the prediction of this life-threatening heart condition.
“We identified a total of 26 protein biomarkers associated with sudden cardiac arrest when cases were compared to controls, of which, 20 differentiated sudden cardiac arrest from coronary artery disease,” said Faye Norby, PhD, a research scientist at the Center for Cardiac Arrest Prevention in the Smidt Heart Institute and first author of the study. “While these biomarkers have the potential to enhance prediction of sudden cardiac arrest, future studies are needed to replicate these findings in a larger group of patients.”
Related Links:
Cedars-Sinai
Latest Molecular Diagnostics News
- Blood Proteins Could Warn of Cancer Seven Years before Diagnosis
- New DNA Origami Technique to Advance Disease Diagnosis
- Ultrasound-Aided Blood Testing Detects Cancer Biomarkers from Cells
- New Respiratory Syndromic Testing Panel Provides Fast and Accurate Results
- New Synthetic Biomarker Technology Differentiates Between Prior Zika and Dengue Infections
- Novel Biomarkers to Improve Diagnosis of Renal Cell Carcinoma Subtypes
- RNA-Powered Molecular Test to Help Combat Early-Age Onset Colorectal Cancer
- Advanced Blood Test to Spot Alzheimer's Before Progression to Dementia
- Multi-Omic Noninvasive Urine-Based DNA Test to Improve Bladder Cancer Detection
- First of Its Kind NGS Assay for Precise Detection of BCR::ABL1 Fusion Gene to Enable Personalized Leukemia Treatment
- Urine Test to Revolutionize Lyme Disease Testing
- Simple Blood Test Could Enable First Quantitative Assessments for Future Cerebrovascular Disease
- New Genetic Testing Procedure Combined With Ultrasound Detects High Cardiovascular Risk
- Blood Samples Enhance B-Cell Lymphoma Diagnostics and Prognosis
- Blood Test Predicts Knee Osteoarthritis Eight Years Before Signs Appears On X-Rays
- Blood Test Accurately Predicts Lung Cancer Risk and Reduces Need for Scans