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Pathology

Image: Histopathology of a colon with adenocarcinoma showing chaotic appearance of glandular pattern (Photo courtesy of Johns Hopkins University).

DNA Blood Test Evaluated for Colorectal Cancer Detection

Tumor-derived aberrant DNA can be detectable in blood and blood tests have the potential to improve screening for colorectal cancer.  More...
11 Jun 2014
Image: Histopathology of chronic obstructive pulmonary disease (COPD) showing hyperplasia of mucous glands and infiltration of the airway wall with inflammatory cells (Photo courtesy of Dr. Paul Kleinschmidt MD).

Breath Test Distinguishes Lung Cancer from Other Pulmonary Diseases

A test of organic compounds in exhaled breath can distinguish patients with lung cancer from patients with chronic obstructive pulmonary disease, and can also define the stage of any cancer present.  More...
11 Jun 2014
Image: ConfirmMDx detects an epigenetic field effect or “halo” associated with the cancerization process at the DNA level in cells adjacent to cancer foci. This epigenetic “halo” around a cancer lesion can be present despite having a normal appearance under the microscope (Photo courtesy of MDxHealth).

DNA Hypermethylation Assay Confirms Negative Prostate Cancer Biopsy Results

A commercially available assay that measures the level of hypermethylated DNA in tissue samples was found to accurately identify negative-for-cancer prostate tissues in more than 88% of cases.  More...
10 Jun 2014
Image: The HumanHT-12 v4 BeadChip Kit uses the DirectHyb Assay and is compatible with the iScan, HiScan, and Bead Array Reader systems (Photo courtesy of Illumina).

Microarray Analysis of Gene Expression Signatures in Blood Samples Provides Biomarker for Higher Cardiovascular Death Risk

Differences in gene expression have been found among a population of coronary artery disease patients that seemed to indicate which of them were at higher risk of dying from the illness.  More...
09 Jun 2014
Image: The anaerobic bacteria Leptotrichia species, Gram-stain from blood culture (Photo courtesy of Mike Dyall-Smith).

Oral Bacteria May Diagnose Pancreatic Cancer

Patients with pancreatic cancer have a different and distinct profile of specific bacteria in their saliva compared to healthy controls and even patients with other cancers or pancreatic diseases.   More...
04 Jun 2014
Image: The RotorGene RG-3000 thermal cycler system (Photo courtesy of Corbett Research).

Gene Mutation Found for Aggressive Form of Pancreatic Cancer

A mutated gene common to adenosquamous carcinoma tumors has been discovered and is the first known unique molecular signature for this rare, but particularly virulent, form of pancreatic cancer.  More...
04 Jun 2014
Image: A Finnigan Surveyor Plus High-Performance Liquid Chromatography (HPLC) instrument (Photo courtesy of Thermo Scientific).

Urinary Test Diagnoses Cancer and Infertility-Causing Parasite

A fast, noninvasive way to test for a cancer-causing parasite that kills hundreds of thousands of people every year has been discovered.   More...
03 Jun 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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