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Pathology

Image: The HTS PAL autosampler (Photo courtesy of Leap Technologies).

Newly Discovered Marker Detects Early Pancreatic Cancer

A marker in the blood that may indicate early development of the pancreatic ductal adenocarcinoma could pave the way for an early detection test.  More...
16 Oct 2014
Image: GS3 prostate cancer: The tissue still has recognizable glands, but the cells are darker. At high magnification, some of these cells have left the glands and are beginning to invade the surrounding tissue or having an infiltrative pattern. This corresponds to a moderately differentiated carcinoma (Photo courtesy of Wikimedia Commons).

PSA Gene Variants Distinguish Patients with Highly Aggressive Prostate Cancer

Cancer researchers have identified three mutations in the KLK3 gene, which codes for prostate specific antigen, associated with biopsy-proven high-aggressive prostate cancer.  More...
15 Oct 2014
Image: Histopathology of non-polyposis colorectal cancer or Lynch Syndrome (Photo courtesy of Dr. L. Marcucci MD).

Genetic Test Would Help Cut Bowel Cancer Spread

Screening families of patients with bowel cancer for a genetic condition would cut their risk of developing bowel, womb, and ovarian cancers.   More...
15 Oct 2014
Image: Histopathology of a colorectal tubular adenoma without high grade dysplasia (Photo courtesy of Nephron).

Blood Test Detects Early and Later-Stage Colorectal Cancers

Despite the existence of screening programs for the disease, colorectal cancer remains the second leading cause of cancer-related death in the USA, partly due to the cost, and to low compliance with colonoscopies and other screening methods such as fecal tests.  More...
06 Oct 2014
Image: An illustration of an epitaxial graphene channel biosensor for detection of targeted 8-hydroxydeoxyguanosine (8-OHdG) biomarker (Photo courtesy of 2D Materials).

Ultrasensitive Graphene Biosensors Detect Cancer Risk Biomarker

An ultrasensitive biosensor utilizing the exceptional electronic and thermal properties of graphene has been used to detect molecules that indicate an increased risk of developing cancer.  More...
05 Oct 2014
Image: The LightCycler 480 Instrument for polymerase chain reactions (Photo courtesy of Roche Applied Science).

Colorectal Cancer Relapses Predicted by Expression of Five Genes

The analysis of five differentially expressed genes could be used to classify colorectal tumors, predict the evolution of the patient and thus take appropriate clinical decisions to prevent relapses.   More...
02 Oct 2014
Image: Telomeres at the end of the chromosomes protecting against DNA deterioration (Photo courtesy of Dr. Daniel Friedland MD).

Chromosome Buffers Improve Understanding of Melanoma

Buffers that guard against damage to the ends of chromosomes could hold the key to a better understanding of malignant melanoma, the deadliest form of skin cancer.  More...
01 Oct 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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