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Pathology

Image: Gross appearance of an opened colectomy specimen containing two adenomatous polyps and one invasive colorectal carcinoma (Photo courtesy of Emmanuelm).

Gene Test Identifies Patients with High Risk Colon Cancer

Proprietary microarray-based gene signature marker can identify patients' recurrence risk within five years after surgery and guides adjuvant chemotherapy treatment decisions. Colon cancer is the second leading cause of cancer mortality among men and women in the USA and the five-year survival rate for individuals with colon cancer is 64.9%.   More...
11 Apr 2016
Image: Micrograph of a needle biopsy specimen of prostate adenocarcinoma, acinar type, the most common type of prostate cancer (Photo courtesy of Wikimedia Commons).

Three Gene Urine Test for Prostate Cancer May Eliminate Invasive Biopsies

A real-time PCR assay that measures levels of RNA generated by three prostate cancer-linked genes may someday replace classical detection methods for this disease and eliminate the need for invasive biopsies.  More...
11 Apr 2016
Image: The NextSeq 500 Series desktop sequencing system (Photo courtesy of Illumina).

Improved “Liquid Biopsy” Technique Enhances Tumor DNA Detection

An improved method has been devised to significantly increase the sensitivity of a technique to identify and sequence DNA from cancer cells circulating in a person's blood. The hope is that such "liquid biopsies" of easily obtained blood samples could one day replace the need to surgically obtain tumor tissue for examination.  More...
10 Apr 2016
Image: Micrograph of pancreatic ductal adenocarcinoma (the most common type of pancreatic cancer) (Photo courtesy of Wikimedia Commons).

Establishment of Biomarker Panel May Lead to Rapid Tests for Early Diagnosis of Pancreatic Cancer

A panel comprising five genetic biomarkers was shown to accurately differentiate among tissues from pancreatic tumors and those taken from various non-malignant sources.  More...
10 Apr 2016
Image: The Parsortix system uses a patented microfluidic technology in the form of a disposable cassette to capture and then harvest circulating tumor cells (CTCs) from blood (Photo courtesy of ANGLE plc).

Parsortix System Detects Prostate Cancer in Clinical Application

The current gold standard for detection is the prostate-specific antigen blood test, which is known to have low sensitivity and low specificity with high levels of false positives, and the digital rectal exam, which is less effective than the PSA test.  More...
06 Apr 2016
Image: Histopathology of a skin section from a patient with superficial spreading malignant melanoma (Photo courtesy of Profs. Leszek Wozniak and Krzysztof W. Zielinski).

Noncoding RNA Gene Linked to Malignant Melanoma

While a large share of the human genome has long been considered “junk DNA” because it does not contribute to protein coding, recent insights indicate that it does produce many noncoding ribonucleic acids that play important roles in essential biological processes and diseases.   More...
05 Apr 2016
Image: Histopathology of colon adenocarcinoma composed of chaotic glandular structures that are lined by one or more rows of cancer cells with or without mucus production (Photo courtesy of the Johns Hopkins University).

Novel Blood Test Detects Colorectal Cancer Recurrence Earlier

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide, accounting for more than 600,000 deaths each year. When diagnosed early, before cancer has spread, the relative five-year survival rate for CRC is 90%, but only about 4 out of 10 CRC cases are detected early.  More...
05 Apr 2016
Platinum Member
Automated Coagulation Analyzer
Hemolumi H6
Gold Member
Clinical Chemistry Assay
Sorbitol Dehydrogenase (SDH)
New
Gastrointestinal Panel
Xpert® GI Panel
New
Alzheimer's Disease Biomarker Assay
Elecsys Phospho-Tau (217P) Plasma


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.