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Pathology

Image: SNTF stained axons (brown) shortly after traumatic brain injury. The undulating course suggests damage to the internal skeleton, and the SNTF stain shows the high calcium concentration-activated enzymes that destroy the axon from the inside out (Photo courtesy of the laboratory of Douglas Smith, MD).

Protein Biomarker Identifies Damaged Brain Wiring After Concussion

Mild traumatic brain injury or concussion is often defined as a brief loss of normal brain function typically following a blow to the head and is by far the most common form of TBI and frequently does not even receive medical attention.  More...
08 Dec 2015

New H&E Tissue Staining Solution Sets New Standard in Histopathology

A new hematoxylin and eosin staining system provides exceptionally high tissue staining quality and efficiency that enhances patient care as well as lab technician safety.  More...
07 Dec 2015
Image: Schematic diagram of a nucleosome which is a section of DNA that is wrapped around a core of proteins and the basis for the NuQ biomarker assays (Photo courtesy of VolitionRx Limited).

NuQ Blood Test Accurately Detects Lung Cancers

Lung cancer is the second most common cancer in men and women, with around 220,000 new cases diagnosed each year and 158,000 deaths in the USA alone and lung cancers are the leading cause of cancer-related death in that country.   More...
06 Dec 2015
Image: The MiSeq Next-Generation Sequencing System (Photo courtesy of University of Lausanne).

Germline Genes Mutations Associated with Pediatric Cancer Predisposition

The prevalence and spectrum of predisposing mutations among children and adolescents with cancer are largely unknown, but knowledge of such mutations may improve the understanding of tumorigenesis, direct patient care, and enable genetic counseling of patients and families.  More...
06 Dec 2015
Image: A micrograph of the target cells (green) sticking to the microarray platform (red) (Photo courtesy of Dr. Michael Hirtz / KIT).

Cancer Cells Detected Before They Form Metastases

A versatile microarray-based platform has been developed that is able to capture single target cells from large background populations as analyses of rare events occurring at extremely low frequencies in body fluids are still challenging.  More...
06 Dec 2015
Image: Ion OneTouch 2 System (Photo courtesy of Thermo Fisher).

Blood Test Detects When Breast Cancer Becomes Resistant to Treatment

A highly sensitive blood test has been developed that can spot when breast cancers become resistant to standard hormone treatment, and it has been demonstrated that this test could guide further treatment.    More...
02 Dec 2015
Image: Scanning electron micrograph of a clump of activated platelets (Photo courtesy of Brown University).

Blood-Based Platelet RNA Tests Detects Cancer

Cancer is primarily diagnosed by clinical presentation, radiology, biochemical tests, and pathological analysis of tumor tissue, increasingly supported by molecular diagnostic tests.  More...
01 Dec 2015
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Immunochromatographic Assay
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.