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Pathology

Image: A tissue sample image created by the new lens-free microscope (Photo courtesy of Prof. Aydogan Ozcan).

Lens-Free Microscope Creates Images from Pathology Slides

A lens-free microscope has been developed that can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive optical microscopes.   More...
31 Dec 2014
Image: A histology slide stained with hematoxylin and eosin (H&E) and the corresponding three-dimensional cancer density map, which facilitate the measurement of spatial proximity to cancer for every single lymphocyte in the image (Photo courtesy of The Institute of Cancer Research).

Gene Expression Correlates with Lymphocyte Infiltration in Breast Cancer

Lymphocytic infiltration is associated with a favorable prognosis and predicts response to chemotherapy in many cancer types, including the aggressive triple-negative breast cancer.  More...
30 Dec 2014
Image: Micrograph of a pleural fluid cytopathology specimen showing mesothelioma (Photo courtesy of Wikimedia Commons).

Mutations in Rare Asbestos-Caused Cancer Identified by Targeted Next-Generation Sequencing

Targeted next-generation sequencing, an advanced genomic analysis tool, was used to identify genes linked to the development of the rare cancer malignant pleural mesothelioma.  More...
29 Dec 2014
Image: Comparison of between normal cervical tissue (top), tissue lesion (second row), photographic image (third row) and corresponding DMAP images (fourth row) (Photo courtesy of Biomedical Optics Express).

Potential New Tool for Cervical Cancer Detection

Photoacoustic imaging has the potential to be a quicker, cheaper, and less-invasive method for detecting and staging cervical cancer, according to a new study.   More...
29 Dec 2014
Image: Location of the Breast cancer 1, early onset (BRCA1) gene on chromosome 17 (Photo courtesy of Armin Kübelbeck).

Genetic Tests for Breast Cancer Detect More Mutations

A new study has demonstrated the ability of a commercial Hereditary Cancer test to detect 105% more mutations in cancer causing genes than conventional Breast Cancer testing alone.  More...
28 Dec 2014
Image: The Nu Plasma II multiple collector inductively coupled plasma mass spectrometry instrument (MC-ICP-MS) (Photo courtesy of Nu Instruments).

Zinc Isotope Test Helps Detect Early Breast Cancer

It may be possible to detect the early signs of breast cancer with a test that measures changes in zinc isotopes, as measurable changes in zinc isotope composition can be detected in breast tissue and could be used as a biomarker for early breast cancer.  More...
23 Dec 2014
Image: Bacteria forming a mixed biofilm on colon cancer tissue (Photo courtesy of Jessica Mark Welch, Blair Rossetti, and Christine Dejea).

Bacterial Biofilms Associated with Colon Cancer

An imaging technology reveals that bacterial biofilms are associated with colon cancer and the discovery draws on a novel way to observe microbial community structure.  More...
21 Dec 2014
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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