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Pathology

Image: A blood film from a patient with bladder cancer showing increased number of neutrophils and band cells (Photo courtesy of MPH).

Reliability Reevaluated for Bladder Cancer Test Prognosis

A blood test that had shown promise in predicting how cancer will progress and what treatments will be most effective for a given patient may not be reliable for either, as results from previous studies are threatened by methodological limitations. More...
08 Nov 2016
Image: The Cholestech LDX analyzer for POC lipid testing (Photo courtesy of Alere).

Early Childhood Screening Helps Prevent Heart Attacks

Familial hypercholesterolemia (FH) is a genetic disorder characterized by high cholesterol levels and is the main inherited cause of early heart disease and without preventive medication young FH adults has about a 10-fold increased risk of a heart attack before the age of 40. More...
08 Nov 2016
Image: A thin preparation pap smear with group of normal cervical cells on left and HPV-infected cells showing features typical of koilocytes: enlarged nuclei and hyperchromasia (Photo courtesy of Ed Uthman, MD).

Cervical Cancer Screening Could Become Less Frequent

Less-intensive screening is needed among women who have been vaccinated against human papillomavirus (HPV), which causes almost all cases of cervical cancer, because the risk of these women developing cervical cancer is quite low. More...
04 Nov 2016
Image: Immunohistochemistry image of invasive squamous cell carcinomas of tonsil tissue showing overexpression of p16, which is a very good surrogate marker for HPV infection (Photo courtesy of David C. Hoak, MD).

New Genetic Factors Linked to HPV-Related Cancers

A new, large-scale genetic study of head and neck cancers shows why some individuals infected with human papillomavirus (HPV) may go on to develop oropharyngeal cancer while others do not. More...
04 Nov 2016
Image: The Vectra automated quantitative pathology imaging system (Photo courtesy of Perkin Elmer).

Collagen Changes Linked to Poor Pancreatic Cancer Prognosis

Risk factors for pancreatic ductal adenocarcinoma (PDAC) progression after surgery are unclear, and additional prognostic factors are needed to inform treatment regimens and therapeutic targets. More...
04 Nov 2016
Image: A histopathology image of hepatocellular carcinoma: the malignant cells seen mostly on the right are well differentiated and interdigitate with normal, larger hepatocytes seen mostly at the left (Photo courtesy of SPL).

Ascitic Fluid Lactoferrin Investigated in Liver Cirrhosis Patients

Although elevated levels of lactoferrin provide a biomarker for inflammatory bowel diseases and colorectal cancer, the clinical significance of these elevated levels in ascitic fluid of patients with ascites caused by liver cirrhosis is limited. More...
03 Nov 2016
Image: The Access Array microfluidic system generates next-generation sequencing (NGS) (Photo courtesy of Fluidigm).

Non-Invasive Assay Improves Surveillance of Solid-Organ Transplants

Patients who have received a solid organ transplant require lifelong immunosuppressive therapy. The threat of transplant rejection due to insufficient drug therapy must be balanced against increased risks of infections and cancer from excessive immunosuppression. More...
28 Oct 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.