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Pathology

Image: The BioMek FXP automation workstation (Photo courtesy of Beckman Coulter).

Innovative Gene Testing Technology Finds Cancer Risks

A new method has been developed for identifying mutations and prioritizing variants in breast and ovarian cancer genes, which will not only reduce the number of possible variants for doctors to investigate, but also increase the number of patients that are properly diagnosed. More...
19 May 2016
Image: A photomicrograph of an abnormal Pap smear showing changes consistent with Human Papilloma Virus (HPV) and Mild Dysplasia. Note the irregular perinuclear cytoplasmic clearing, which is the key characteristic of identifying HPV visually on a Pap smear (Photo courtesy of Dr. Cynthia D Booth, MD).

Combining Two Diagnostic Tests Drastically Reduces Cancer Miss Rates

The Papanicolaou (Pap) test is recommended for women between 21 and 65 years old as a screening test for cervical cancer. Women 30 and older who are negative on co-testing may wait as long as five years for their next testing, but physicians still recommend annual examinations. More...
17 May 2016

Study Finds Excessive Testing Prescribed for Monoclonal Gammopathy Patients

A retrospective analysis has determined that the tests for M-protein that physicians routinely order to help diagnose and monitor patients with the age-related immune disorder monoclonal gammopathy (MG), often do not benefit the patient. Pathologists who performed the study have proposed an optimizing algorithm for more effective decision-making based on the evidence for clinical value. More...
17 May 2016
Image: A histologic view of an endometrial adenocarcinoma showing many abnormal nuclei (Photo courtesy of Wikimedia Commons).

Study Finds Five New Genetic Risk Loci for Endometrial Cancer

Genome-wide association studies (GWAS) have revealed five previously unknown risk loci for endometrial cancer. More...
16 May 2016
Image: A structural model of the Bim protein (Photo courtesy of Wikimedia Commons).

Levels of Bim Protein in T-cells Reflect Success of Anti–PD-1 Cancer Therapy

Measurement of levels of Bim (BCL-2-interacting mediator of cell death) protein in circulating T-cells of cancer patients may provide a less invasive strategy to predict and monitor responses to anti–PD-1 therapy. More...
16 May 2016
Image: The MRX microplate reader (Photo courtesy of Dynatech Medical Products).

Blood Test Detects Breast Cancer Spread Earlier

More sensitive, non-invasive tests are required for secondary breast cancer, which occurs when new tumors grow in the bone, liver, lung or brain, to make diagnosis easier and for treatment to begin as early as possible. More...
12 May 2016
Image: The MassARRAY Dx analyzer system (Photo courtesy of Agena Bioscience).

Diagnostic Tests For Lung And Colon Cancer Launched In Europe

A unique combination of reliability, sensitivity, ease of use, and cost-effectiveness for targeted genetic testing for cancer has now become available to molecular pathologists. More...
12 May 2016
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Hematology Analyzer
Medonic M32B
Portable Electronic Pipette
Mini 96
Sample Transportation System
Tempus1800 Necto
ESR Analyzer
TEST1 2.0


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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