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Pathology

Image: A histopathology of acute pancreatitis showing hemorrhage, parenchymal necrosis, and fat necrosis (Photo courtesy of Kathryn Lindsey, MD).

Mild-to-Moderate Hypertriglyceridemia Leads to Acute Pancreatitis

Pancreatitis is very painful and it may lead to fatalities and until now, medical science has connected the risk of developing this illness to gallstone, a high intake of alcohol and very high concentrations of blood fats or triglycerides. More...
23 Nov 2016
Image: A histopathology of rhabdoid meningiomas characterized by enlarged epithelioid cells with large nuclei and prominent nucleoli. Bright intracellular secretions (black arrows) are present. Note that the sizes of these vacuoles are several times the size of the nuclei. Intranuclear pseudoinclusions are also present (white arrows) (Photo courtesy of Kar-Ming Fung, MD, PhD).

Molecular Signature Identified for Aggressive Brain Tumor

Meningiomas are the most common primary brain tumors, but the term encompasses over a dozen subtypes that range from benign to highly aggressive. Rhabdoid meningiomas are classified as highly aggressive due to their high rates of recurrence and mortality, but the experience and outcomes for patients with this rare form of brain tumor vary widely. More...
23 Nov 2016
Image: The Cytosponge, a well-tolerated and effective means to sample the lining of the esophagus (Photo courtesy of the University of North Carolina).

Cytosponge Test Could Replace Uncomfortable Endoscopies

A ‘sponge on a string’ pill or Cytosponge test can identify which people with a condition called Barrett’s esophagus who have a low risk of developing esophageal cancer, sparing them uncomfortable endoscopies. More...
23 Nov 2016
Image: The upgraded Cartagenia Bench Lab 5.0 addresses inherent challenges of interpreting and reporting on genomic variants data (Photo courtesy of Agilent Technologies).

Software Platform Provides Capabilities for Somatic Variation Analysis

An upgraded information-processing platform enables clinical genetics and molecular pathology laboratories to achieve higher performance and efficiency in somatic variation analysis of tumor-tissue sequencing data and in reporting of tissue-typing results, among other features. More...
22 Nov 2016
Image: A micrograph of a diffuse large B cell lymphoma (DLBCL) (Photo courtesy of Wikimedia Commons).

Personalized Cancer Diagnostics Based on Circulating Tumor DNA Profiling

Cancer researchers have demonstrated that profiling of circulating tumor DNA (ctDNA) revealed molecular determinants that enabled them to predict adverse outcomes in patients with diffuse large B cell lymphoma and that could be developed into a method for personalized diagnosis. More...
22 Nov 2016
Image: The BD LSRFortessa flow cytometer cell analyzer (Photo courtesy of Becton Dickinson).

Tumor Markers Reveal Lethality of Bladder Cancers

Bladder cancer is the fourth most common cause of cancer-related death among men in the USA and more than 75,000 new cases will be diagnosed this year and more than 16,000 people will die from this disease. More...
17 Nov 2016
Image: A histopathology of prostate cancer showing multiple poorly formed glands with ill-defined lumina and/or incomplete nuclear complement (Photo courtesy of European Urology).

Identification of Gene Defects Helps Prostate Cancer Treatment

The current method of treating prostate cancer involves identifying gene defects, which could help with the diagnosis of cancer and the development of individualized cancer treatments for patients. More...
16 Nov 2016
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.