Pathology
DNA-Based Test Determines Degree Of Liver Fibrosis
Non-alcoholic fatty liver disease (NAFLD) accounts for the majority of liver disease burden in the Western world. Liver biopsy remains the gold standard test to accurately stage fibrosis in patients with NAFLD, but it is invasive and carries risks. More...28 Apr 2016
Study Identifies Mechanism Underlying a Form of Sensory Nerve Damage
Researchers have discovered a mechanism that underlies induction of peripheral neuropathy (PN) by the chemotherapeutic agent paclitaxel, raising the prospects for developing treatments for this and possibly also for certain other forms of PN. The work may also lead to companion diagnostics to identify patients who would benefit from these new therapies. More...27 Apr 2016
Prostate Needle Biopsy Biomarker Predicts Tumor Aggressiveness
A new study demonstrates the ability to measure and evaluate biomarkers from ribonucleic acid expression data obtained from prostate needle biopsies. The data demonstrate a high concordance in the genomic signatures between needle biopsy samples and post-prostatectomy tissue samples. More...11 Apr 2016
Gene Test Identifies Patients with High Risk Colon Cancer
Proprietary microarray-based gene signature marker can identify patients' recurrence risk within five years after surgery and guides adjuvant chemotherapy treatment decisions. Colon cancer is the second leading cause of cancer mortality among men and women in the USA and the five-year survival rate for individuals with colon cancer is 64.9%. More...11 Apr 2016
Three Gene Urine Test for Prostate Cancer May Eliminate Invasive Biopsies
A real-time PCR assay that measures levels of RNA generated by three prostate cancer-linked genes may someday replace classical detection methods for this disease and eliminate the need for invasive biopsies. More...11 Apr 2016
Improved “Liquid Biopsy” Technique Enhances Tumor DNA Detection
An improved method has been devised to significantly increase the sensitivity of a technique to identify and sequence DNA from cancer cells circulating in a person's blood. The hope is that such "liquid biopsies" of easily obtained blood samples could one day replace the need to surgically obtain tumor tissue for examination. More...10 Apr 2016
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In Other News
Establishment of Biomarker Panel May Lead to Rapid Tests for Early Diagnosis of Pancreatic Cancer
Parsortix System Detects Prostate Cancer in Clinical Application
Noncoding RNA Gene Linked to Malignant Melanoma
Novel Blood Test Detects Colorectal Cancer Recurrence Earlier
Hereditary Cancer Test Identifies Deleterious Mutations in Endometrial Cancer
High Risk HPV Multiplex Assay Clinically Validated
Sensitive Method Detects Early Amyloidosis in Humans
Novel Blood Test Developed for Alzheimer's Diagnosis
Multiple Diseases Detected via DNA Released from Dying Cells
Prostate Cancer Diagnosed from Urinary Ribonucleic Acid
Automated Microfluidic Device Simultaneously Detects HIV RNA and Antibodies
Early Stage Breast Cancer Recurrence Linked to High Leukocyte Ratio
Blood Test Accurately Detects Idiopathic Pulmonary Fibrosis
Age Should Be Considered in Developing Diagnostic Assays
Developing POC Tests for Alzheimer’s to Improve Monitoring and Management of the Disease
Fibrin Network Changes in Neonates After Cardiopulmonary Bypass
Blood Test Detects Chronic Traumatic Encephalopathy During Life
Blood Test Gives Early Warning of Melanoma Relapse
Enzyme Signpost Points to Better Bowel Cancer Test
Novel Biochip Combines Antibody Binding and Electronic Counting to Simplify Diagnosis of HIV/AIDS
Frozen Section Analysis for Breast Cancer Saves Time
Biomarker Identifies Uveal Melanoma Patients at Risk for Metastasis
CSF Biomarker Elevated in Early Stages of Alzheimer's Disease
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
