Pathology

Image: Immunohistochemistry of estrogen-receptor-positive (ER (+)) breast cancer (Photo courtesy of Biocare Medical).

Genetic Test Discovered for Predicting Cancer Recurrence

Treatment failure, due to drug resistance, still remains a major obstacle for more effective anti-cancer therapy and personalized medicine. In estrogen-receptor-positive (ER (+)) breast cancer, approximately 40% to 50% of patients eventually develop tamoxifen-resistance. More...
04 Oct 2017

HPV Testing Detects More Precancerous Lesions

Human papillomavirus (HPV) testing detects a higher number of precancerous cervical lesions than cytology-based Papanicolaou (Pap) smears in a female population including a proportion offered HPV vaccination according to a new study. More...
03 Oct 2017

Immunocompromised Patients at Risk for Blastomycosis

Most invasive fungal infections in immunocompromised patients are caused by Zygomycetes, Aspergillus, and Candida, but literature about Blastomyces infection in immunocompromised patients has been sparse. More...
28 Sep 2017

Urinary Tract Biopsy Correlates Urothelial Carcinoma Diagnosis

Urothelial carcinoma (UCC), also known as transitional cell carcinoma (TCC) is a type of cancer that typically occurs in the urinary system. It is the most common type of bladder cancer and cancer of the ureter. More...
28 Sep 2017

$Image: Immunohistochemistry for anaplastic lymphoma kinase (ALK) in peritoneal mesothelioma shows separation of the 5\' (green) and 3\' (red) probe signals in each of the three cases with diffuse strong ALK expression (Photo courtesy of the JAMA Network).$

Genetic Cause of Peritoneal Mesothelioma Discovered

Mesothelioma is a rare and aggressive tumor that, in many cases, results from exposure to asbestos, but other causes of the disease have emerged, including treatment with high-intensity therapeutic radiation and, more recently, an inherited genetic mutation. More...
28 Sep 2017

Image: The cobas EGFR Mutation Test v2 CE-IVD identifies the epidermal growth factor receptor (EGFR) gene in the DNA from non-small cell lung cancer (NSCLC) patients (Photo courtesy of Roche Molecular Diagnostics).

Blood Test Predicts Treatments for Lung Cancer Patients

Traditionally, lung cancer diagnosis has relied solely on lung biopsies, an invasive procedure which many patients are too unwell to tolerate. A simple test, which can detect gene mutations in tumor DNA from blood samples, is giving new choices to lung cancer patients with faster diagnosis and improved access to life changing drugs. More...
27 Sep 2017

Image: The Dionex Ultimate 3000 high-performance liquid chromatography (HPLC) system (Photo courtesy of the University of Texas at Austin).

Protein Network Mutations Impact Revealed in Bowel Cancer

The role proteins play in predicting how common mutations affect proteins in the cancer cells has been investigated and also whether such proteins are important in predicting the cancer's response to treatment. More...
22 Sep 2017

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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.