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Pathology

Image: The Hybrid Capture 2 modular system used for processing the digene HC2 HPV DNA Test of human papillomavirus infections (Photo courtesy of Qiagen).

HPV Testing Detects More Precancerous Lesions

Human papillomavirus (HPV) testing detects a higher number of precancerous cervical lesions than cytology-based Papanicolaou (Pap) smears in a female population including a proportion offered HPV vaccination according to a new study. More...
03 Oct 2017
Image: A photomicrograph showing Blastomyces organisms stained with Periodic Acid Schiff (PAS). Note the budding organism (arrow) and the underlying pyogranulomatous inflammatory reaction in the background (Photo courtesy of University of Alabama at Birmingham).

Immunocompromised Patients at Risk for Blastomycosis

Most invasive fungal infections in immunocompromised patients are caused by Zygomycetes, Aspergillus, and Candida, but literature about Blastomyces infection in immunocompromised patients has been sparse. More...
28 Sep 2017
Image: Histopathology of transitional carcinoma of the urinary bladder from a transurethral biopsy. This exophytic papillary tumor shows multiple finger-like projections lined by multiple layers of urothelium (transitional epithelium) (Photo courtesy of Pathpedia).

Urinary Tract Biopsy Correlates Urothelial Carcinoma Diagnosis

Urothelial carcinoma (UCC), also known as transitional cell carcinoma (TCC) is a type of cancer that typically occurs in the urinary system. It is the most common type of bladder cancer and cancer of the ureter. More...
28 Sep 2017
Image: Immunohistochemistry for anaplastic lymphoma kinase (ALK) in peritoneal mesothelioma shows separation of the 5\' (green) and 3\' (red) probe signals in each of the three cases with diffuse strong ALK expression (Photo courtesy of the JAMA Network).

Genetic Cause of Peritoneal Mesothelioma Discovered

Mesothelioma is a rare and aggressive tumor that, in many cases, results from exposure to asbestos, but other causes of the disease have emerged, including treatment with high-intensity therapeutic radiation and, more recently, an inherited genetic mutation. More...
28 Sep 2017
Image: The cobas EGFR Mutation Test v2 CE-IVD identifies the epidermal growth factor receptor (EGFR) gene in the DNA from non-small cell lung cancer (NSCLC) patients (Photo courtesy of Roche Molecular Diagnostics).

Blood Test Predicts Treatments for Lung Cancer Patients

Traditionally, lung cancer diagnosis has relied solely on lung biopsies, an invasive procedure which many patients are too unwell to tolerate. A simple test, which can detect gene mutations in tumor DNA from blood samples, is giving new choices to lung cancer patients with faster diagnosis and improved access to life changing drugs. More...
27 Sep 2017
Image: The Dionex Ultimate 3000 high-performance liquid chromatography (HPLC) system (Photo courtesy of the University of Texas at Austin).

Protein Network Mutations Impact Revealed in Bowel Cancer

The role proteins play in predicting how common mutations affect proteins in the cancer cells has been investigated and also whether such proteins are important in predicting the cancer's response to treatment. More...
22 Sep 2017
Image: Histopathology of breast cancer: intraductal carcinoma, comedo type, with distended duct with intact basement membrane and central tumor necrosis (Photo courtesy of Peter Abdelmessieh, DO, MSc).

Cholesterol Diagnosis Related to Breast Cancer Risk

Breast cancer is a malignancy that begins when cells grow abnormally in breast tissue. Although men can also develop breast cancer, it is much more common in women. Among women around the globe, breast cancer is the most common cancer and the fifth most common cause of cancer death. In 2012, nearly 1.7 million new cases, a quarter of all new cancer cases in women, were diagnosed worldwide. More...
22 Sep 2017
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.