Pathology
Potential Noninvasive Biomarker of EoE Disease Activity Identified
Researchers have identified a potential blood-based marker of disease activity for the severe and often painful food allergic disease eosinophilic esophagitis (EoE) – possibly leading to a blood test, which could spare EoE patients, often children, the discomfort and risk of the currently used invasive endoscopic monitoring procedures. More...24 May 2016
Innovative Gene Testing Technology Finds Cancer Risks
A new method has been developed for identifying mutations and prioritizing variants in breast and ovarian cancer genes, which will not only reduce the number of possible variants for doctors to investigate, but also increase the number of patients that are properly diagnosed. More...19 May 2016
Combining Two Diagnostic Tests Drastically Reduces Cancer Miss Rates
The Papanicolaou (Pap) test is recommended for women between 21 and 65 years old as a screening test for cervical cancer. Women 30 and older who are negative on co-testing may wait as long as five years for their next testing, but physicians still recommend annual examinations. More...17 May 2016
Study Finds Excessive Testing Prescribed for Monoclonal Gammopathy Patients
A retrospective analysis has determined that the tests for M-protein that physicians routinely order to help diagnose and monitor patients with the age-related immune disorder monoclonal gammopathy (MG), often do not benefit the patient. Pathologists who performed the study have proposed an optimizing algorithm for more effective decision-making based on the evidence for clinical value. More...17 May 2016
Levels of Bim Protein in T-cells Reflect Success of Anti–PD-1 Cancer Therapy
Measurement of levels of Bim (BCL-2-interacting mediator of cell death) protein in circulating T-cells of cancer patients may provide a less invasive strategy to predict and monitor responses to anti–PD-1 therapy. More...16 May 2016
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In Other News
Diagnostic Tests For Lung And Colon Cancer Launched In Europe
Blood Test Developed for Parkinson’s Disease
Blood Biomarker Assay Detects Prostate Cancer Early
Non-Invasive Prostate Cancer Test Developed Using Exosomal RNA
Liquid Biopsy Clinical Application Demonstrated for Metastatic Breast Cancer
Liver Cancer May Be Diagnosed from Altered Sugar Metabolism
Genetic Test Reduces Post-Surgery Chemotherapy for Breast Cancer Patients
Noninvasive Test Detects Colorectal Cancer in Unscreened Patients
Patterns of MicroRNA Expression Distinguish Patients with Asthma and Allergic Rhinitis
Tissue Biomarker Identified For Dementia With Lewy Bodies
Genetic Link Confirmed Between DCIS And Invasive Disease
DNA-Based Test Determines Degree Of Liver Fibrosis
Study Identifies Mechanism Underlying a Form of Sensory Nerve Damage
Biomarker Predicts Breast Cancer Risk in Asymptomatic Women
Prostate Needle Biopsy Biomarker Predicts Tumor Aggressiveness
Gene Test Identifies Patients with High Risk Colon Cancer
Three Gene Urine Test for Prostate Cancer May Eliminate Invasive Biopsies
Improved “Liquid Biopsy” Technique Enhances Tumor DNA Detection
Establishment of Biomarker Panel May Lead to Rapid Tests for Early Diagnosis of Pancreatic Cancer
Parsortix System Detects Prostate Cancer in Clinical Application
Noncoding RNA Gene Linked to Malignant Melanoma
Novel Blood Test Detects Colorectal Cancer Recurrence Earlier
Hereditary Cancer Test Identifies Deleterious Mutations in Endometrial Cancer
The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.