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Pathology

Image: AI software reads unstructured data sources & ID at-risk cancer patients (Photo courtesy of Azra AI)

AI Platform Identifies 99% of Positive Cancer Cases in Pathology Reports

A new artificial intelligence (AI) platform disrupts the manual and repetitive processes in healthcare to identify positive cancer diagnosis and incidental findings in real time, classify those diagnoses by primary site, and route those patients to cancer navigators and other staff to immediately start the cancer care journey. More...
14 Mar 2022
Image: The Chemagic Magnetic Separation Module I is the complete solution for preparation of nucleic acids from various sample material, such as blood, tissue, bacteria, plasma, saliva etc. (Photo courtesy of PerkinElmer Chemagen Technologie)

Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases

Roughly one in every three children with a type of kidney cancer known as Wilms tumor, or nephroblastoma, carry germline alterations implicated in hereditary cancer risk, new research suggests — findings that have prompted more widespread genetic testing for Dutch children with the condition. More...
08 Mar 2022
Image: Photomicrograph of cytomegalovirus colitis (Photo courtesy of Nephron)

Immunohistochemistry Evaluated for Tissue-Invasive Cytomegalovirus in Gastrointestinal Mucosal Biopsies

Cytomegalovirus (CMV) immunohistochemistry (IHC) is the most widely used method to diagnose CMV infection/reactivation in tissues in a pathology laboratory. More...
04 Mar 2022
Image: Strong nuclear and cytoplasmic p16 staining of a section from an HPV+ oropharynx tumor. Lymphocytes (blue arrow) and endothelial cells (black arrow) are unstained (Photo courtesy of Jonathon McHugh, MD)

TTMV-HPV DNA Biomarker Predicts Recurrence of Oropharynx Cancer

A large, multi-institutional study demonstrates that a blood test to detect circulating tumor DNA can accurately predict recurrence of HPV-driven oropharyngeal cancer following treatment. Results also indicate that the biomarker test may detect recurrent disease earlier than imaging or other standard methods of post-treatment surveillance, allowing physicians to personalize treatment more quickly for patients whose cancer returns. More...
03 Mar 2022
Image: Lipoprotein(a), or Lp(a), is a distinctive particle with two components: a lipoprotein core that resembles LDL, along with a shell that contains apolipoprotein(a), or apo(a).

Two Important Cardiovascular Disease Risk Factors Operate Independently

Determination of blood levels of the cholesterol-rich biomarker lipoprotein(a) [Lp(a)] and the coronary artery calcium (CAC) score are independently associated with risk of developing coronary artery disease and may be useful concurrently for guiding therapy approaches to prevent its occurrence . More...
02 Mar 2022
Image: Schematic diagram of the IMMray PanCan-d assay that relies on the IMMray microarray technology, where single chain fragment antibodies are printed onto a slide in a measured amount as a microarray of different antibody biomarkers (Photo courtesy of Immunovia)

Immunoassay Detects Pancreatic Cancer in People at High Risk

An immunoassay was able to detect pancreatic cancer in high-risk individuals and with high sensitivity and specificity. More...
28 Feb 2022
Image: Oxford BioDynamics Plc has announced the successful clinical validation and US launch of its Checkpoint Inhibitor Response Test (Photo courtesy of Oxford BioDynamics)

First-of-Its-Kind Clinical Blood Test Predicts Cancer Patient’s Response to ICI Immunotherapy

A first-of-its-kind clinical blood test predicts the likelihood of a cancer patient’s response to an essential, widely used class of therapeutics – Immune Checkpoint Inhibitors (ICIs) – including anti-PD-L1 and anti-PD-1 immunotherapies. More...
28 Feb 2022
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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