Pathology
Genomic Screening Can Identify Risk for Amyloid Cardiomyopathy
Transthyretin amyloidosis (ATTR) a is a rare, progressive disease characterized by the abnormal buildup of amyloid deposits composed of misfolded transthyretin protein in the body’s organs and tissues. ATTR can be hereditary and lead to a spectrum of other diseases and conditions, including cardiomyopathy, a common precursor to heart failure. More...15 Dec 2021
Cystic Pancreatic Lesion Bacteria Are Precursors to Pancreatic Cancer
Pancreatic cancer (PC) is one of the most aggressive and lethal types of cancer. The 5-year survival rate at the time of diagnosis is about 10%, as approximately 80%–85% of patients present either unresectable or metastatic disease. PC accounts for roughly 459,000 new cases and 432,000 deaths. More...08 Dec 2021
Roche Introduces AI-Based Digital Pathology RUO Algorithms for Evaluation of Breast Cancer Markers
Roche (Basel, Switzerland) has announced the research use only (RUO) launch of three new automated digital pathology algorithms, uPath Ki-67 (30-9), uPath ER (SP1) and uPath PR (1E2) image analysis for breast cancer, which are important biomarkers for breast cancer patients. More...08 Dec 2021
Targeted RNA-Sequencing Panel Detects Gene Fusions in Solid Tumors
Increasingly, rearrangements resulting in gene fusions have been revealed in multiple tumor types across diverse organ systems. These gene fusions can drive tumorigenesis by altering gene expression and activity. Timely and reliable detection of fusions provides useful information to the pathologist and clinical team. More...07 Dec 2021
Specific Biomarker Investigated for Triple-Negative Breast Cancer Diagnosis
Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expression and comprises a heterogeneous group of breast cancers that exhibit distinct morphologic features and biological behavior. More...30 Nov 2021
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.