Microbiology
Enzyme Immunoassays Developed for Serodiagnosis of Human Leptospirosis
The laborious microscopic agglutination test (MAT) is the gold standard serologic test for laboratory diagnosis of leptospirosis. We developed EIA based serologic assays using recombinant proteins (rLigA, rLigB, rLipL32) and whole-cell extracts from eight Leptospira serovars as antigen and assessed the diagnostic performance of the new assay. More...14 Mar 2022
Fecal Microbiome Signature Predicts Pancreatic Cancer Risk
Researchers have identified a molecular signature of 27 microorganisms in stool samples that is able to predict whether an individual is at high risk of developing pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer. More...10 Mar 2022
Diagnostic Biomarker Predicts Risk of Opisthorchiasis Cholangiocarcinoma
Opisthorchiasis is caused by an infection with fish-borne liver flukes of the genus Opisthorchis. Opisthorchiasis frequently leads to chronic inflammation in the biliary tract and is classified as a group 1 biological carcinogen by the International Agency for Research on Cancer: a definitive risk for cholangiocarcinoma (CCA). More...10 Mar 2022
Paper-Based Portable Diagnostic Platform Accurately Detects Mosquito-Borne Diseases Under Field Conditions
Field trails conducted in Latin America have shown that a paper-based portable diagnostic platform could accurately detect patients with mosquito-borne diseases with sensitivities equivalent to laboratory PCR tests. More...09 Mar 2022
Repeatability And Reproducibility of a Handheld Quantitative G6PD Diagnostic
Novel treatment regimens for the radical cure of P. vivax malaria are more effective than current options but require prior quantitative G6PD testing. The reference method for quantitative G6PD measurement is spectrophotometry but, due to its operational characteristics, is not suitable for routine use. Furthermore, poor inter-laboratory reproducibility of spectrophotometry has prevented quantitative global definitions of G6PD deficiency. SD Biosensor (ROK) have developed a novel handheld “Biosensor” device (G6PD STANDARD), which measures G6PD activity within two minutes and has operational characteristics suited to point of care diagnosis. More...03 Mar 2022
C. Difficile Colonization Among Children in Resource-Limited Settings
This study describes the epidemiology and risk factors for colonization among children in the etiology, risk factors, and interactions of enteric infections and malnutrition. Also explored was whether C. difficile detection contributed to longer-term health outcomes. More...02 Mar 2022
Microbiome and Metabolome Features Characterized for the Cardiometabolic Disease Spectrum
Scientists have already discovered that the gut microbiome is altered in people with chronic heart disease. They subsequently identified compounds that are produced by the diseased microbiome, for instance a bacterial compound called trimethylamine (TMA) that after modification in the liver of the human host causes arteriosclerosis. More...28 Feb 2022
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MALDI-TOF Can Predict Antimicrobial Resistance in Clinical Samples
MCDA-LFB Assay Developed for Rapid Detection of Legionnaires’ Disease
Commercial RT-PCR Tests Compared to Culture for Bacterial Gastroenteritis
BD Introduces Smart Connected Robotics to Automate Microbial Identification
Skin Infections Confirmed as a Cause of Acute Rheumatic Fever
Menstrual Blood Testing With Capture Sequencing Detects High-Risk Human Papillomavirus
Parkinson’s Disease Patients Have More Inflammatory Bacteria in Their Noses
Calprotectin Levels Vary When Measured in Different Matrices for COVID-19
Bacterial Communities Diverge in The Lower Airways of CF Children
Rapid, Highly Accurate Test Developed to Detect Viruses
Circulating ACE2 Activity Predicts Mortality and Severity in COVID-19 Patients
Beta-Lactamase Detection Reagent Rapidly Diagnoses Urinary ESBL-Producing Pathogens
Immunoprofiling HTLV-1 Blood Samples Show Altered Innate Cell Responsiveness
Cystic Pancreatic Lesion Bacteria Are Precursors to Pancreatic Cancer
Rapid Diagnostic Testing Analyzed in Suspected Meningitis Diagnosis
Same Day Test Identifies Secondary Infections in COVID-19 Patients
The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
