Microbiology
Albumin-Related Ratios Investigated in HBV-Associated Decompensated Cirrhosis
Identification of effective and accurate prognostic biomarkers for hepatitis B virus-associated decompensated cirrhosis (HBV-DeCi) is challenging. This study was designed to determine and compare the prognostic value of albumin-related ratios (blood urea nitrogen-to-albumin ratio [BAR], C-reactive protein-to-albumin ratio [CAR], prothrombin time-international normalized ratio-to-albumin ratio [PTAR], neutrophil count-to-albumin ratio [NAR], and D-dimer-to-albumin ratio [DAR]) in HBV-DeCi patients. More...25 Mar 2022
Expression, Microbiome Features Provide Pre-Treatment Lung Function Clues for Pediatric Patients (Science Translational Medicine University of California at San Francisco
Microbial community and host gene expression features in lung samples may provide pre-treatment clues to risky lung function features in children receiving bone marrow transplants from healthy donor individuals, new research suggests. More...15 Mar 2022
Enzyme Immunoassays Developed for Serodiagnosis of Human Leptospirosis
The laborious microscopic agglutination test (MAT) is the gold standard serologic test for laboratory diagnosis of leptospirosis. We developed EIA based serologic assays using recombinant proteins (rLigA, rLigB, rLipL32) and whole-cell extracts from eight Leptospira serovars as antigen and assessed the diagnostic performance of the new assay. More...14 Mar 2022
Fecal Microbiome Signature Predicts Pancreatic Cancer Risk
Researchers have identified a molecular signature of 27 microorganisms in stool samples that is able to predict whether an individual is at high risk of developing pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer. More...10 Mar 2022
Diagnostic Biomarker Predicts Risk of Opisthorchiasis Cholangiocarcinoma
Opisthorchiasis is caused by an infection with fish-borne liver flukes of the genus Opisthorchis. Opisthorchiasis frequently leads to chronic inflammation in the biliary tract and is classified as a group 1 biological carcinogen by the International Agency for Research on Cancer: a definitive risk for cholangiocarcinoma (CCA). More...10 Mar 2022
Paper-Based Portable Diagnostic Platform Accurately Detects Mosquito-Borne Diseases Under Field Conditions
Field trails conducted in Latin America have shown that a paper-based portable diagnostic platform could accurately detect patients with mosquito-borne diseases with sensitivities equivalent to laboratory PCR tests. More...09 Mar 2022
Repeatability And Reproducibility of a Handheld Quantitative G6PD Diagnostic
Novel treatment regimens for the radical cure of P. vivax malaria are more effective than current options but require prior quantitative G6PD testing. The reference method for quantitative G6PD measurement is spectrophotometry but, due to its operational characteristics, is not suitable for routine use. Furthermore, poor inter-laboratory reproducibility of spectrophotometry has prevented quantitative global definitions of G6PD deficiency. SD Biosensor (ROK) have developed a novel handheld “Biosensor” device (G6PD STANDARD), which measures G6PD activity within two minutes and has operational characteristics suited to point of care diagnosis. More...03 Mar 2022
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In Other News
C. Difficile Colonization Among Children in Resource-Limited Settings
Microbiome and Metabolome Features Characterized for the Cardiometabolic Disease Spectrum
P-O-C Assay Detects Respiratory Syncytial Virus in Older Adults
New Pathogen Detection Assay Pairs Molecular Inversion Probes, Next-Generation Sequencing
Chromosomally Normal Miscarriage Is Associated With Vaginal Dysbiosis
Rapid COVID Test Developed Solves Problems With LAMP Sensitivity
Intestinal Microbiota Determines the Risk of MDRO Acquisition
Qiagen’s New Generation of QuantiFERON TB Test Gains Chinese Approval and Renewed WHO Recommendation
ABO Blood Group Related to Specific Immune Response to Anti-SARS-CoV-2
MALDI-TOF Can Predict Antimicrobial Resistance in Clinical Samples
MCDA-LFB Assay Developed for Rapid Detection of Legionnaires’ Disease
Commercial RT-PCR Tests Compared to Culture for Bacterial Gastroenteritis
BD Introduces Smart Connected Robotics to Automate Microbial Identification
Skin Infections Confirmed as a Cause of Acute Rheumatic Fever
Menstrual Blood Testing With Capture Sequencing Detects High-Risk Human Papillomavirus
Parkinson’s Disease Patients Have More Inflammatory Bacteria in Their Noses
Calprotectin Levels Vary When Measured in Different Matrices for COVID-19
Bacterial Communities Diverge in The Lower Airways of CF Children
Rapid, Highly Accurate Test Developed to Detect Viruses
Circulating ACE2 Activity Predicts Mortality and Severity in COVID-19 Patients
Beta-Lactamase Detection Reagent Rapidly Diagnoses Urinary ESBL-Producing Pathogens
Immunoprofiling HTLV-1 Blood Samples Show Altered Innate Cell Responsiveness
Cystic Pancreatic Lesion Bacteria Are Precursors to Pancreatic Cancer
The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
