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Microbiology

Image: The BD Accuri C6 Plus Flow Cytometer (Photo courtesy of BD Biosciences)

Microbiome and Metabolome Features Characterized for the Cardiometabolic Disease Spectrum

Scientists have already discovered that the gut microbiome is altered in people with chronic heart disease. They subsequently identified compounds that are produced by the diseased microbiome, for instance a bacterial compound called trimethylamine (TMA) that after modification in the liver of the human host causes arteriosclerosis. More...
28 Feb 2022
Image: The Xpert Xpress Flu/RSV Assay is intended as an aid in the diagnosis of influenza and respiratory syncytial virus infections (Photo courtesy of Cepheid)

P-O-C Assay Detects Respiratory Syncytial Virus in Older Adults

The point-of-care Xpert Xpress Flu/RSV test appeared nearly as accurate as routine real-time RT-PCR for detecting respiratory syncytial virus (RSV) infections in older adults, a Dutch study found. More...
22 Feb 2022
Image: Oxford Nanopore Technologies’ MinIon sequencer is the only portable real-time device for DNA and RNA sequencing (Photo courtesy of Bradley Kroner (RDECOM)

New Pathogen Detection Assay Pairs Molecular Inversion Probes, Next-Generation Sequencing

Next-generation sequencing is rapidly finding footholds in numerous microbiological fields, including infectious disease diagnostics. Molecular inversion probe (MIP) technology can be coupled with next-generation sequencing (NGS) for targeted, multiplexed pathogen detection. More...
21 Feb 2022
Image: The ABI PRISM 3100 Genetic Analyzers is an automated capillary electrophoresis systems that can separate, detect, and analyze fluorescent-labeled DNA fragments in one run (Photo courtesy of Michaela Pereckas)

Chromosomally Normal Miscarriage Is Associated With Vaginal Dysbiosis

Emerging evidence supports an association between vaginal microbiota composition and risk of miscarriage; however, the underlying mechanisms are poorly understood. We aim to investigate the vaginal microbial composition and the local immune response in chromosomally normal and abnormal miscarriages and compare this to uncomplicated pregnancies delivering at term. More...
17 Feb 2022
Image: Equipment required for the smaRT-LAMP testing technology would cost less than USD100 (Photo courtesy of Michael Mahan, PhD)

Rapid COVID Test Developed Solves Problems With LAMP Sensitivity

Researchers from the University of California, Santa Barbara have developed an isothermal amplification-based SARS-CoV-2 and influenza test that could retail for as little as $2 while addressing a key problem with loop-mediated isothermal amplification tests — false positive results. More...
14 Feb 2022
Image: The Quantus Fluorometer is a compact, dual-channel fluorometer designed to provide highly sensitive fluorescent detection when quantifying nucleic acids (Photo courtesy of Promega)

Intestinal Microbiota Determines the Risk of MDRO Acquisition

Colonization and infection by multidrug-resistant organisms (MDRO) remains a public health problem. This is particularly important in intensive care units (ICUs) where the risk of MDRO acquisition/colonization results from the selective pressure associated with prolonged broad-spectrum antibiotic treatment. More...
10 Feb 2022
Image: QIAreach QuantiFERON-TB (Photo courtesy of QIAGEN N.V.)

Qiagen’s New Generation of QuantiFERON TB Test Gains Chinese Approval and Renewed WHO Recommendation

QIAGEN N.V. (Venlo, Netherlands) has announced that its QuantiFERON tuberculosis (TB) testing solution has gained additional momentum with the approval of the fourth generation of this modern gold standard test in China and a new endorsement from the World Health Organization (WHO). More...
08 Feb 2022
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.