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Microbiology

Image: Vibrio cholerae bacterial colonies cultivated on Thiosulfate-Citrate-Bile-Sucrose (TCBS) agar medium (Photo courtesy of the CDC - US Centers for Disease Control and Prevention).

Immunochromatographic Lateral Flow Device Developed for Cholera

Currently, the gold standard to detect Vibrio cholerae is still the bacterial culture method, which is laborious, time-consuming and lacks sensitivity; however several modern diagnostic methods have been developed.  More...
28 Apr 2014
Image: The Genome Analyzer IIx (Photo courtesy of Illumina).

Genome Sequencing of MRSA Infection Predicts Disease Severity

Bacterial pathogens, such as methicillin-resistant Staphylococcus aureus, cause disease in part due to toxicity, or the bacterium's ability to damage a host's tissue.  More...
24 Apr 2014
Image: A photomicrograph of Mycobacterium leprae, the small brick-red rods, taken from a leprosy skin lesion (Photo courtesy of Centers of Disease Control and Prevention).

Molecular-Based Techniques Diagnose Leprosy

The classic tools to diagnose leprosy are based on bacillary counts and histopathology, but these have been facing hurdles, especially in distinguishing latent infection from active disease and diagnosing paucibacillary clinical forms.  More...
23 Apr 2014
Image: The Bond-III automated stainer (Photo courtesy of Leica Microsystems).

Genetic Trigger Found for RSV-Induced Infant Hospitalizations

A viral protein has been pinpointed that plays a major role in making respiratory syncytial virus the most common cause of hospitalization in children under one year of age.   More...
21 Apr 2014
Image: Scanning electron micrograph of the spirochete Borrelia burgdorferi, long, slender bacteria that typically take on a coiled shape. Infection with this bacterium causes Lyme disease (Photo courtesy of Tina Carvalho).

Strain-Specific Immunity Discovered for Lyme Disease

Many patients treated for early Lyme disease incur another infection in subsequent years, suggesting that previous exposure to Borrelia burgdorferi may not elicit a protective immune response.  More...
17 Apr 2014
Image: Scanning electron micrograph of Brucella abortus (Photo courtesy of the Czech University of Life Science).

Blood Culture Diagnostic Techniques Compared for Human Brucellosis

Isolation of the bacteria Brucella is the gold standard in the laboratory diagnosis of brucellosis and as the organism is intracellular, the number of circulating bacteria is usually low.   More...
16 Apr 2014
Image: Loop mediated isothermal amplification (LAMP) detection kit for malaria (Photo courtesy of Eiken Chemical Co. Ltd.).

Improved LAMP Test Diagnoses Symptomatic Falciparum Malaria

The molecular diagnosis of malaria by nucleotide amplification requires sophisticated and expensive instruments, typically found only in well-established laboratories.  More...
09 Apr 2014
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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