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Microbiology

Image: The Twista portable real-time fluorometer (Photo courtesy of TwistDx Ltd).

Mobile DNA Test Developed for HIV

An efficient test to detect signs of human immunodeficiency virus and its progress in patients in low-resource settings is being developed using recombinase polymerase amplification.   More...
19 Jun 2014
Image: Electron micrograph of the bacterium Bordetella pertussis, the causative agent of pertussis (Photo courtesy of Sanofi Pasteur).

Oral Fluid Testing Established for Pertussis

Existing surveillance systems for pertussis or whooping cough are inadequate and tend to be biased toward identifying severe cases in infants, as reflected by extremely high reported incidence for this age group.  More...
19 Jun 2014
DIASOURCE (A Biovendor Company)
Image: The BrukerAutoflex MALDI-TOF mass spectrometer (Photo courtesy of Bruker-Daltonics).

Cutaneous Leishmaniasis Species Identified by Mass Spectrometry

Cutaneous leishmaniasis is caused by several Leishmania species that are associated with variable outcomes before and after therapy and optimal treatment decision is based on an accurate identification of the infecting species.  More...
18 Jun 2014
Image: Flower patterned nitrocellulose paper substrate used to develop a novel multiplex, rapid diagnostic test for hepatitis C infection (Photo courtesy of the Chinese Academy of Medical Sciences and the American Chemical Society).

Rapid Diagnostic Test for Hepatitis C Developed with Scrapbooking Tool

Scientists have used a novel approach to develop a paper-based multiplex diagnostic immunoassay that could help curb the hepatitis C pandemic.  More...
17 Jun 2014
Image: Transmission electron micrograph of Candidatus Neoehrlichia mikurensis (A). The arrows indicate the thin, rippled, bileaflet outer membrane which is characteristic of the bacterium (B), the irregular, narrow periplasmic space between inner and outer membranes, also characteristic (C) and canalicular system of the endothelial cell (D) (Photo courtesy of Yasuko Rikihisa).

New Tick-Borne Disease Threatens Primarily Immune Suppressed Persons

A newly discovered tick-borne bacterium known as Candidatus Neoehrlichia mikurensis has been implicated in six cases of the disease in Sweden.  More...
16 Jun 2014
Image: The Mini-FLOTAC device for the detection of helminthic eggs (Photo courtesy of Prof. Giuseppe Cringoli).

Alternative Methods Tested for Detection of Soil-Transmitted Helminths

The commonly used diagnostic technique for the detection of soil-transmitted helminths is the Kato-Katz method, but it has low sensitivity arising mainly from the nonrandom distribution of eggs in stool and day-to-day variation in egg output.   More...
12 Jun 2014
Image: ADVIA Centaur XP Immunoassay System (Photo courtesy of Siemens).

Commercial Treponemal Assays Compared for Syphilis Detection

Treponemal tests for detecting syphilis should be sufficiently sensitive and specific, especially when used as the first-line method in reverse-algorithm testing.  More...
12 Jun 2014
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