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Microbiology

Image: Specificity assay of Yersinia F1-strips. Six Yersinia strains (105 CFU/mL each) were applied on Yersinia-F1-strips. Strip 1: Y. pestis yreka; 2: Y. mollaretii; 3: Y. frederiksenii; 4: Y. pseudotuberculosis; 5: Y. enterocolitica; 6: Y. intermedia; 7: PCB buffer (Photo courtesy of National Defense Medical Center).

Lateral-Flow Assay Rapidly Detects Plague Bacteria

Plague caused by Yersinia pestis is a known flea-borne disease that can trigger large epizootics among the rodent population. Humans that live in environments close to these rodents can contract the bubonic plague either through direct contact with infected animals or through transmission by infective flea bites. More...
28 Aug 2018
Image: Coherent fluctuation nephelometry analyses microbiological concentrations in urine (Photo courtesy of Medtechnopark).

Coherent Fluctuation Nephelometry Used to Diagnose Bacteriuria

Urinary tract infections (UTI) belong to the most common infectious diseases, making 20% to 49% of all nosocomial infections. For correct UTI diagnosis, the knowledge about the presence of microorganisms in urine is needed and such diagnosis is traditionally carried out by culture methods using solid nutrient media. More...
20 Aug 2018
Image: Mannitol salt agar plate with oxacillin showing methicillin-resistant Staphylococcus aureus (Photo courtesy of Medical College, Pondicherry).

Time To Blood Culture Positivity Predicts Infective Endocarditis

Blood cultures are used to detect the presence of bacteria or fungi in the blood, to identify the type present, and to guide treatment. Testing is used to identify a blood infection (septicemia) that can lead to sepsis, a serious and life-threatening complication. More...
16 Aug 2018
Image: The FilmArray System is the new standard for syndromic infectious disease diagnostics (Photo courtesy of BioFire Diagnostics).

Multiplex Testing Speeds Up CNS Infection Diagnosis

A variety of viral, bacterial, and fungal pathogens cause infections of the central nervous system (CNS), which range in severity from mild and self-limiting to severe and life-threatening. Initial symptoms like headache, fever, photophobia, and neck stiffness are not organism-specific so cannot be used to guide therapy. More...
16 Aug 2018
Image: Positive and negative results detected by the lateral flow immunochromatographic assay AcQuickDx test for Angiostrongylus cantonensis (Photo courtesy of Faculty of Medicine Siriraj Hospital).

Immunochromatographic Test Rapidly Diagnoses Parasitic Infection

The rat lungworm Angiostrongylus cantonensis is a food-borne zoonotic parasite that causes eosinophilic meningitis in humans. Suspected cases of A. cantonensis infection can only be confirmed by finding the nematodes in cerebral spinal fluid (CSF) of the patients. More...
15 Aug 2018
Image: Spiral-shaped Helicobacter pylori is the only bacteria known to colonize the human stomach. An estimated 50% of humans harbor H. pylori in their gut, but only some develop ulcers or stomach cancer (Photo courtesy of Boston University).

Diagnostic Accuracy in H. pylori Fecal Test Assessed

Helicobacter pylori (H. pylori) infection occurs among 48.5% of the general population worldwide, with high geographic variability. It is the leading cause of chronic/atrophic gastritis, peptic ulcer, gastric lymphoma, gastric carcinoma, and some extra-gastric disorders. More...
15 Aug 2018
Image: The NeuMoDx GBS assay is run on the 288 molecular system (Photo courtesy of NeuMoDx Molecular).

FDA Clears Diagnostic Assay for Group B Strep

Group B Streptococcus (GBS) is a Gram-positive bacterium found in 10% to 35% of healthy adults and is a commonly found bacterium within the human body. A person who carries GBS and does not present symptoms of GBS disease is said to be “colonized” with GBS. More...
10 Aug 2018
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