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Immunology

Image: Heart rate variability changes with levels of inflammatory serum markers. Left: normal levels of IL-12 and ICAM-1 associated with normal heart rate variability. Right: increased levels of IL-12 and ICAM-1 resulting in decreased heart rate variability. IL-12 is known to associate with arterial stiffness in healthy (Photo courtesy of BMC)

Elevated Interleukin-12/23p40 Indicates Dysfunctional Heart Rate Variability in T2D

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in type 2 diabetes (T2D), accounting for approximately 50% of all deaths. Cardiovascular functions, including heart rate, heart contractility, and blood pressure, are regulated by autonomic sympathovagal balance. More...
08 Feb 2022
Image: Schematic diagram of image-enabled cell sorting, developed at BD Biosciences and  tested by European Molecular Biology Laboratory (Photo courtesy of BD Bioscience)

High-Speed Fluorescence Image-Enabled Cell Sorting Tested

Cell sorting through flow cytometry is a technique that enables scientists to identify and sort individual cells based on specific characteristics of each cell in order to study them in more detail, evaluate how each cell may react to a new drug or perform other single cell studies. More...
03 Feb 2022
Image: The MACSQuant Analyzer 16 is engineered to expand the horizons of automated data acquisition with 16 optical parameters (Photo courtesy of Miltenyi Biotec)

ABO Blood Group Related to Specific Immune Response to Anti-SARS-CoV-2

Markers of the protective humoral response, such as total anti-SARS-CoV-2 immunoglobulins and neutralizing antibodies, have been observed to decrease in convalescent individuals, even though a potential long-lasting humoral B-cell memory subset was detected. More...
31 Jan 2022
Image: The High Capacity RNA-to-cDNA Kit is a streamlined reverse transcription kit designed for optimum performance with TaqMan Gene Expression Master Mix, Power SYBR Green PCR Master Mix, and other PCR enzymes (Photo courtesy of Thermo Fisher Scientific)

Melanoma Test Offers Reassurance of Low Risk of Cancer Spread

Cutaneous melanoma is an aggressive form of skin cancer with an increasing worldwide incidence, particularly in the younger population. Although treatment for patients with metastatic melanoma has improved remarkably in the last decade, principally with targeted therapies and immune checkpoint modulators, there are still no consistently beneficial treatments for patients with metastatic disease. More...
25 Jan 2022
Image: The Human Cytokine/Chemokine/Growth Factor Convenience 45-Plex ProcartaPlex Panel, 384 well (lyophilized beads) enables the study of immune function by analyzing 45 protein targets in a single well using Luminex FLEXMAP 3D and INTELLIFLEX instruments (Photo courtesy of Thermo Fisher Scientific)

Biomarkers Linked to Autism Risk Identified

Autism spectrum disorders (ASDs) comprise a set of pervasive neurodevelopmental conditions characterized by restricted and repetitive behavior patterns and impairments in social interaction and communication. More...
20 Jan 2022
Image: The Bio-Plex 200 system is a suspension array system which offers protein and nucleic acid analysis and a reliable multiplex assay solution that permits analysis of up to 100 biomolecules in a single sample (Photo courtesy of Bio-Rad)

Immune System Can Detect Disease During Pregnancy

Pregnancy is a challenge for the mother's immune system from the outset. Half of the genes in the fetus are foreign to her body. The immune system has to strike a balance between tolerating the fetus and protecting the mother and fetus from infections. Throughout the pregnancy, an immunological balance takes place between mother and child. More...
13 Jan 2022
Image: Advanced stage of stomach cancer with stomach tissue array, including pathology grade, malignant tumors (TNM) and clinical stage (Photo courtesy of SuperBioChips Laboratories)

Natural Killer Cell-Associated Markers Investigated in Gastric Cancer

Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. Although the survival rates of GC patients have increased with proper screening systems, standardized surgical protocols, and development of chemotherapy regimens, the general outcome of GC patients, especially those in advanced stages, remains poor. More...
11 Jan 2022
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.