Immunology
Proinflammatory T Cell Polarization Investigated in Early Knee Osteoarthritis
In osteoarthritis (OA), the cartilage in the knee joint gradually wears away. As the cartilage wears away, it becomes frayed and rough, and the protective space between the bones decreases. This can result in bone rubbing on bone, and produce painful bone spurs. Osteoarthritis develops slowly and the pain it causes worsens over time. More...01 Feb 2021
Alzheimer's Progression Tracked with Blood Biomarkers
Alzheimer disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles of hyperphosphorylated tau in the brain. These neuropathological changes are believed to take part in a cascade of events that result in a characteristic neurodegeneration pattern followed by progressive cognitive impairment. More...28 Jan 2021
Early Differences in Cytokine Production Distinguish Severity of COVID-19
Most COVID-19 patients experience asymptomatic/mild symptoms, but some suffer critical symptoms requiring intensive care. It is important to determine how asymptomatic/mild patients react to SARS-CoV-2 infection and suppress virus spread. More...27 Jan 2021
Mismatch Repair/Microsatellite Instability Evaluated Using Cytology Effusion Specimens
DNA mismatch repair (MMR) status is routinely assessed in colorectal and endometrial carcinoma as a method of cancer prevention, surveillance in patients with Lynch syndrome and their families, and for prognostic, predictive, and therapeutic implications. More...25 Jan 2021
Tryptophan Metabolism Is Dysregulated in Individuals with Fanconi Anemia
Fanconi anemia (FA) is a complex genetic disorder frequently associated with progressive marrow failure and a strong predisposition to early malignancies, particularly squamous cell carcinomas and hepatocellular carcinomas. More...20 Jan 2021
Basophil Activation Test Predicts Pediatric Wheezing Prognosis
Although asthma is a common chronic airway inflammatory disease in children, the natural history of asthma remains unknown. It is difficult to diagnose asthma in children aged under five years because of the complexity of wheezing phenotypes at that age. More...20 Jan 2021
Increased Serum Neurofilament Light Portend Worse Prognosis in COVID-19
There is emerging evidence for multifarious neurological manifestations of COVID‐19, while little is known whether they reflect structural damage to the nervous system. The most commonly reported neurological manifestations of COVID-19 were myalgia, headache, altered sensorium, hyposmia, and hypogeusia. More...19 Jan 2021
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In Other News
Immunohistological Detection of Small Particles of Echinococcus Species Evaluated
Serum Pentosidine Levels Measured in Systemic Lupus Erythematosus
Angiopoietin-Like 2 Is a Biomarker for Diabetic Foot Patients
Combination Urinary Biomarker Panel Detects Pancreatic Cancer Earlier
Chitotriosidase Expression in Sarcoidosis Limited by Gene Expression
Preliminary Predictive Criteria Identified for COVID-19 Cytokine Storm
Multiplex Bead-Based Immunoassay Validated for Non-Invasive Bladder Cancer Detection
Chronic Lymphocytic Leukemia Increases Peripheral Blood Hematopoietic Stem Cells
Novel Biomarkers Predict the Development of Incident Heart Failure
Osteopontin Linked to Progressive Lung Scarring in Scleroderma Patients
Scrub Typhus Enzyme Linked Immunoassay Evaluated for Accuracy
Newly Developed Immunoassay Evaluated for Infectious Diseases
Novel Biomarker Candidate for Amyotrophic Lateral Sclerosis Explored
Elevated Soluble C5b9 Biomarker Found in SARS-Cov-2 Infected Children
Gene Expression Signature Traces Nonalcoholic Fatty Liver Disease Progression
Biomarker Evaluated for Early Detection of Congenital Heart Disease
Anti‐Citrullinated Antibodies Associated with NET Formation in Rheumatoid Arthritis
Triple FIT Surpasses Single Sigmoidoscopy in CRC Screening
Kininogen-1 Protein Linked to Early Cognitive Impairment in Parkinson’s
Single-Tube Multimarker Assay Estimates Preeclampsia Risk
Cytokine Profiles Characterized in Primary Sjögren´s Syndrome Patients
Distinct Inflammatory Profiles Distinguish COVID-19 From Influenza
SARS-CoV-2 RNA Test Assessed Among Recovered COVID-19 Patients
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.