Immunology
Flow Cytometric Immunophenotyping Assessed for Classic Hodgkin Lymphoma
The diagnosis of classic Hodgkin lymphoma (CHL) requires morphologic and immunophenotypic identification of neoplastic Hodgkin and Reed-Sternberg cells (collectively referred to as HRS cells) intermixed with a background of reactive lymphocytes, histiocytes, plasma cells, and eosinophils. More...24 Mar 2022
Biomarker Panel for Risk of Early Respiratory Failure Following Hematopoietic Cell Transplantation
Allogeneic hematopoietic cell transplantation (HCT) is a life-saving therapy used for malignant and nonmalignant diseases. However, post-HCT pulmonary complications continue to be a significant problem. When severe, pulmonary complications can result in respiratory failure (RF), affecting 10% to 23% of patients. More...23 Mar 2022
Serum Extracellular Vesicle Arginase 1 Measured In T2DM
Serum extracellular vesicle (EV)-derived arginase 1 (ARG 1) plays a critical role in diabetes-associated endothelial dysfunction. This study was performed to determine the levels of serum EV-derived ARG 1 in T2DM and non-T2DM participants and to examine the association of serum EV-derived ARG 1 with T2DM incidence. More...18 Mar 2022
Enzyme Immunoassays Developed for Serodiagnosis of Human Leptospirosis
The laborious microscopic agglutination test (MAT) is the gold standard serologic test for laboratory diagnosis of leptospirosis. We developed EIA based serologic assays using recombinant proteins (rLigA, rLigB, rLipL32) and whole-cell extracts from eight Leptospira serovars as antigen and assessed the diagnostic performance of the new assay. More...14 Mar 2022
Diagnostic Biomarker Predicts Risk of Opisthorchiasis Cholangiocarcinoma
Opisthorchiasis is caused by an infection with fish-borne liver flukes of the genus Opisthorchis. Opisthorchiasis frequently leads to chronic inflammation in the biliary tract and is classified as a group 1 biological carcinogen by the International Agency for Research on Cancer: a definitive risk for cholangiocarcinoma (CCA). More...10 Mar 2022
Different Assay Evaluated for Thyroglobulin and Thyroglobulin Antibodies
International guidelines recommend fixed cut-off values for thyroglobulin (Tg). These cut-offs do not take potential assay differences into account. This study aimed to evaluate if different assays for Tg and Tg antibodies (TgAb) affect management guidance for differentiated thyroid cancer (DTC) patients. More...07 Mar 2022
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In Other News
Low Levels of IL-39 Associated With Autoimmune Thyroid Disease
Immunoassay Detects Pancreatic Cancer in People at High Risk
Chromosomally Normal Miscarriage Is Associated With Vaginal Dysbiosis
Novel Immune-Profiling Method Reports Specific Immune Cell Types Using Only DNA from Blood
Elevated Interleukin-12/23p40 Indicates Dysfunctional Heart Rate Variability in T2D
High-Speed Fluorescence Image-Enabled Cell Sorting Tested
ABO Blood Group Related to Specific Immune Response to Anti-SARS-CoV-2
Melanoma Test Offers Reassurance of Low Risk of Cancer Spread
Biomarkers Linked to Autism Risk Identified
Immune System Can Detect Disease During Pregnancy
Natural Killer Cell-Associated Markers Investigated in Gastric Cancer
Regulatory and Other Rheumatoid Factors Analyzed in RA Patients
Association Between Helicobacter pylori With Nonalcoholic Fatty Liver Disease Assessed
Biomarker FR+CTC Explored for Breast Cancer Diagnosis
Benchtop Cell Sorter Validated in Biosafety Containment Setting
Tissue Counterpart to Monoclonal B-Cell Lymphocytosis Characterized
Causal Effects of Inflammatory Protein Biomarkers on Inflammatory Diseases
Long-Term Storage Stability of Corticotropin Investigated
New Blood Test Detects Local Immune Activity Without Painful Biopsies and Expensive Imaging
Pulmonary Eosinophilia Indicates Onset of Allergic Bronchopulmonary Aspergillosis
Immunoprofiling HTLV-1 Blood Samples Show Altered Innate Cell Responsiveness
Assay Developed for Patient-Specific Monitoring and Treatment for Ovarian Cancer
Inflammatory Cytokines Measured in Infants Born to Preterm Preeclamptic Mothers
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.