Immunology

Allogeneic Stem Cell Transplants Improve Microbiome, Immune Cells
Past studies have suggested ties between microbial diversity and favorable allogeneic hematopoietic stem cell transplantation (allo-HCT) outcomes, or transplants involving stem cells from healthy donors. The interactions between the gut microbial community and the immune system can influence an individual's response to a bone marrow transplant to treat leukemia, lymphoma, multiple myeloma, and other blood conditions. More...30 May 2022

Autoantibodies Combined With Tumor Markers Detect Lung Cancer
Lung cancer (LC) is one of the most common cancers in the world and is the primary cause of cancer-related death. According to the pathological type, LC can be categorized into small cell LC (SCLC) and non-small cell LC (NSCLC). NSCLC includes squamous cell carcinoma (LSC), adenocarcinoma (LAC), and large cell cancer. More...26 May 2022

Elecsys Androstenedione Immunoassay Evaluated and Compared
Androstenedione (ASD) is a biomarker used in the diagnostic workup of hyperandrogenism, congenital adrenal hyperplasia, premature adrenarche, and polycystic ovary syndrome (PCOS). Androstenedione is the precursor of testosterone and estrone and is produced in the gonads and adrenal glands. More...20 May 2022

Combining RDTs Determines Dengue Immune Status
Dengue is an emerging arboviral infectious disease (DENV), transmitted through the bite of an Aedes mosquito that burdens much of the urbanized tropical and subtropical world. Current dengue diagnostics are primarily concerned with capturing active infections, thus no such method exists for determining primary or post-primary DENV infections, at the point of care. More...18 May 2022

Biomarker Proenkephalin Investigated in Diagnosis of Acute Kidney Injury
Liver transplantation (LT) is the only treatment available for patients with end-stage liver disease, such as liver cancer or acute and subacute liver failure. Among the various types of postoperative organ damage, acute kidney injury (AKI) is particularly prevalent, developing in 5% to 20% of patients undergoing major non-cardiac surgery. More...12 May 2022

Biochemical Abnormalities Among Celiac Disease Patients Referred for Antibody Testing
Celiac disease (CD) is a chronic disease occurring in all age groups and affecting approximately 1% of the population, although many cases of CD remain undiagnosed. This condition is caused by an abnormal immune response in genetically susceptible individuals triggered by the ingestion of gluten proteins from wheat, rye and barley. More...09 May 2022

Immunohistochemistry Biomarkers Used to Subtype Gastric Intestinal Metaplasia
Gastric cancer (GC) is the fifth most common and third most lethal cancer globally. Patients with GC are often asymptomatic, with presentation occurring at advanced stage, and a low 5-year survival rate in most countries. Intestinal metaplasia is considered a key pivot point in the Correa model of GC. More...04 May 2022
In Other News
Antibody Test Identifies Scleroderma Patients at High Risk for Pulmonary Hypertension
Cytokine Signature Identifies COVID-19 Patients With Worst Prognosis
Single-Cell Proteomics of Localized Prostate Cancer Defines Disease Heterogeneity
New BD Assay Speeds Discovery in Autoimmune Disorders, Immuno-Oncology, and Infectious Diseases
Tumor Suppressor Adenomatous Polyposis Coli Regulates T Lymphocyte Migration
Neurofilament Light Biomarker Linked With Parkinson's Disease
Lateral Flow Immunoassay Developed for Detecting Yersinia Pestis
Serum Antinuclear Antibody Correlated in Hispanic Pediatric Patients With NFLD
Pediatric Antiphospholipid Syndrome Diagnosis Methods Reassessed
Double-Antigen Sandwich ELISA Detects Antibodies to Trypanosoma cruzi
Flow Cytometric Immunophenotyping Assessed for Classic Hodgkin Lymphoma
Biomarker Panel for Risk of Early Respiratory Failure Following Hematopoietic Cell Transplantation
Serum Extracellular Vesicle Arginase 1 Measured In T2DM
Enzyme Immunoassays Developed for Serodiagnosis of Human Leptospirosis
Diagnostic Biomarker Predicts Risk of Opisthorchiasis Cholangiocarcinoma
Different Assay Evaluated for Thyroglobulin and Thyroglobulin Antibodies
Immunohistochemistry Evaluated for Tissue-Invasive Cytomegalovirus in Gastrointestinal Mucosal Biopsies
Low Levels of IL-39 Associated With Autoimmune Thyroid Disease
Immunoassay Detects Pancreatic Cancer in People at High Risk
Chromosomally Normal Miscarriage Is Associated With Vaginal Dysbiosis
Novel Immune-Profiling Method Reports Specific Immune Cell Types Using Only DNA from Blood
Elevated Interleukin-12/23p40 Indicates Dysfunctional Heart Rate Variability in T2D
High-Speed Fluorescence Image-Enabled Cell Sorting Tested
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.