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Immunology

Image: Immunofluorescence pattern of endomysial antibodies produced using serum from a patient with celiac disease on monkey esophagus with a fluorescein isothiocyanate (FITC) conjugate (Photo courtesy of Simon Caulton).

Serum Assay Evaluated for Celiac Disease Screening

Celiac Disease is an autoimmune enteropathy triggered by the ingestion of gluten-containing grains in genetically susceptible individuals and it damages the small intestine mucosa leading to villous atrophy, crypt hyperplasia and intraepithelial lymphocytic infiltrate.  More...
07 Jun 2015
Image: Computed tomography scan (CT) of a patient with brain trauma showing cerebral contusions, hemorrhage within the hemispheres, subdural hematoma, and skull fractures (Photo courtesy of Drs. T. Rehman, R. Ali, I. Tawil, and H. Yonas).

Blood Test Detects Traumatic Brain Injury Reducing Unnecessary Imaging

A simple blood test to measure brain-specific proteins released after a person suffers a traumatic brain injury can reliably predict both evidence of TBI on radiographic imaging and injury severity.  More...
02 Jun 2015
Image: Egg of Schistosoma haematobium in a wet mount of urine concentrates, showing the characteristic terminal spine (Photo courtesy of US Centers for Disease Control and Prevention).

Urine Circulating Anodic Antigen Test Diagnoses Schistosomiasis

An accurate diagnosis is essential and should be adapted to the specific stage of a schistosomiasis control program and parasitological methods to detect Schistosoma eggs in stool are widely used.  More...
27 May 2015
Image: The MassARRAY mass spectrometer (Photo courtesy of Agena Bioscience).

New Light Shed on the Cause of Chronic Fatigue Syndrome

The transient receptor potential superfamily in humans comprises 27 cation channels with permeability to monovalent and divalent cations and these channels are widely expressed within humans on cells and tissues and have significant sensory and regulatory roles on most physiological functions.  More...
27 May 2015
Image: The INNOTEST enzyme-linked immunosorbent assay kits for Alzheimer disease biomarkers (Photo courtesy of Fujirebio-Europe).

Small Molecule Detects Alzheimer's Disease at Early Stages

A high level of a small molecule called D-serine have been identified as associated with cognitive decline in Alzheimer’s disease and holds the potential to represent a novel and effective biomarker for AD.   More...
26 May 2015
Image: IBSchek Blood Test kit for irritable bowel syndrome (Photo courtesy of Commonwealth Laboratories Inc.).

Definitive Tests for Irritable Bowel Syndrome Developed

In the clinical evaluation of chronic diarrhea, common differential diagnoses include diarrhea-predominant irritable bowel syndrome, inflammatory bowel disease and celiac disease.   More...
24 May 2015
Image: The nuclear magnetic resonance AVANCE III spectrometer (Photo courtesy of Bruker).

Blood Markers Help Predict Infant Heart Surgery Outcome

Inflammation and metabolism are closely interlinked and both undergo significant dysregulation following surgery for congenital heart disease, contributing to organ failure and morbidity.  More...
20 May 2015
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Immunochromatographic Assay
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Automated MALDI-TOF MS System
EXS 3000
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.