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Immunology

Image: Tissue smear from a patient infected with Leishmania infantum showing numerous protozoan bodies phagocytized by macrophages (Photo courtesy of Dr. Yutaka Tsutsumi).

Cytokine Release Assays Tests for Leishmaniasis in Transplant Recipients

Cytokine release assays have been used to determine the prevalence of Leishmania infantum infection in solid organ transplant recipients living in an area where the organism is endemic following an outbreak.  More...
09 Nov 2015
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Surface Marker Allows New Diagnostic Approaches for Sarcoidosis

A new strategy has been developed to determine monocyte subsets involved in diseases that could help facilitate the diagnosis of sarcoidosis and may improve respective patient management.  More...
08 Nov 2015
Image: The “PD-L1 IHC 28-8 pharmDx” immunohistochemical assay identifies PD-L1 expression levels on the surface of non-small-cell lung cancer (NSCLC) tumor cells. It is the only diagnostic assay FDA-approved to assess survival benefit associated with OPDIVO (nivolumab) therapy for patients with non-squamous NSCLC (Photo courtesy of Dako Denmark).

FDA Approves First of its Kind Companion Dx for Lung Cancer Patients

The US Food and Drug Administration have approved the first complementary diagnostic test to support use of OPDIVO for non-squamous non-small-cell lung cancer therapy.  More...
02 Nov 2015
Image: The Bond-Max automated immunostainer (Photo courtesy of Leica Biosystems).

Prognostic Index Identifies Risk of Testicular Cancer Relapse

The assessment of just three features can identify those at most at risk of relapse of a common kind of testicular cancer known as non-seminomatous germ cell tumor even where there is no evidence of tumor spread.   More...
02 Nov 2015
Image: Schematic diagram of how microtubules disintegrate with Alzheimer\'s disease (Photo courtesy of US National Institute on Aging).

Blood Test Can Accurately Detect Alzheimer's Disease

A blood test that can accurately detect the presence of Alzheimer's disease is being developed which would give physicians an opportunity to intervene at the earliest, most treatable stage.   More...
01 Nov 2015
Image: Transmission electron micrograph (TEM) highlights the particle envelope of a single, spherical-shaped Middle East Respiratory Syndrome Coronavirus (MERS-CoV) virion (Photo courtesy of US National Institute of Allergy and Infectious Diseases).

Serological Assays Compared for MERS-Coronavirus Infection

Middle East respiratory syndrome poses a major threat to global public health and validated serological assays are important for diagnosis and for seroepidemiology to define prevalence and risk factors.   More...
28 Oct 2015
Image: Dual energy X-ray absorptiometry (DXA) scan of a hip for bone density measurement (Photo courtesy of Dr. Anthony Morrow).

Cytokine Serum Levels Increased in Osteoporosis

Interleukin 31 is a proinflammatory cytokine mediating multiple immune functions, whose involvement in a wide range of diseases, such as atopic dermatitis, inflammatory bowel diseases and cutaneous lymphomas.   More...
28 Oct 2015
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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