Immunology
Lab Profiles Differentiate MIS-C From Severe Pediatric COVID-19
Initial reports from the Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) pandemic described children as being less susceptible to Coronavirus Disease 2019 (COVID-19) than adults. Subsequently, a severe and novel pediatric disorder termed Multisystem Inflammatory Syndrome in Children (MIS-C) emerged. More...19 Aug 2020
IFN‐γ Release Assay Helps Diagnose Hemophagocytic Lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH), either primary (pHLH, or Familiar, FHL) or secondary is a life‐threatening hyper‐inflammatory syndrome, characterized by massive and uncontrolled activation of macrophages and T cells, causing fever, cytopenia and liver dysfunction with coagulopathy. More...14 Aug 2020
Renal Expression of Immunomodulators in Diabetic Nephropathy
Diabetic nephropathy (DN) is a chronic microvascular complication that affects about 20% to 30% of patients with type 2 diabetes mellitus (T2DM). It is considered the leading cause of end-stage renal failure requiring renal replacement therapy. More...12 Aug 2020
Serological Dipstick Assay Developed for Melioidosis
The Gram-negative environmental pathogen Burkholderia pseudomallei, causes the severe disease melioidosis. It is highly endemic in southeast Asia and northern Australia, but recent studies suggest that it is also present in many other parts of the world where it is severely underreported. More...05 Aug 2020
Dual Role Discovered for Interleukin-17A in Autoimmune Uveitis
Autoimmune uveitis (AU) is an inflammatory process of the uveal components of the eye, due to an autoimmune reaction to self-antigens or caused by an innate inflammatory reaction secondary to an external stimulus. It can present as an isolated entity or associated with a systemic autoimmune or autoinflammatory disease. More...04 Aug 2020
Melatonin Levels in Parkinson’s Patients Linked to Non-Motor Symptoms
Parkinson’s disease (PD) is a complex neurodegenerative disease characterized by the loss of dopaminergic neurons in the pars compacta (SNpc), resulting in the classic motor manifestations in PD patients. The clinical diagnosis of PD mainly relies on the presence of motor symptoms as the disease progresses. More...21 Jul 2020
Immunogenomic Landscape of Hematological Malignancies Mapped
The reaction of the body's immune system against cancer can be thought of as a cycle. Cancer cells contain proteins that differ from proteins in other tissue. Their components, known as antigens, have to be presented to the T cells of the immune system by the cancer cells. More...20 Jul 2020
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In Other News
Cancer Cells Reprogram Immune Cells to Assist in Metastasis
Clonal Hematopoiesis of Indeterminate Potential Associated with hsC-Reactive Protein
Fully-Automated Calprotectin Immunoassay Validated for IBD Patients
RNA Sequencing as Alternative to Immunohistochemistry in Cancer Diagnostics
Immune Cells Hampered Fighting Soft Tissue and Bone Sarcomas
Blood Test Could Predict Multiple Sclerosis Progression
Diagnostic Assay Developed for Unclassified Severe Combined Immune Deficiency
Detection Rate of Monoclonal Gammopathy of Undetermined Significance Determined
Certain Cytokines Not Associated with Severity of COVID-19 Symptoms
Presepsin Values Evaluated as Sepsis Severity Markers
Biomarkers Evaluated for Lung Disease Severity in Cystic Fibrosis
Two Serodiagnostic Tests Compared for Loiasis in Non-Endemic Area
Increasingly Efficient Serological Tests Developed with Electrochemiluminescence
Tumor Mutation and Immune Microenvironment Revealed in Colorectal Cancer
Serological Exposure Markers Developed for Vivax Malaria
Endogenous Testosterone Levels Associated with Risk of Diabetes
Cytokine Signatures of Tertian Malaria Infection Profiled During Pregnancy
Silver Nanocubes Make Point-of-Care Diagnostics Easier to Read
Initial Immune Response After Dengue Virus Infection Identified
Immune Microenvironment Changes Contribute to Early-Stage Multiple Myeloma
Immune Responses Evaluated for Tick-Borne Encephalitis
High-Throughput T Cell Profiling Technique Developed
Antibody Detection Is Critical for COVID-19 Diagnosis
The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.