Hematology
Qiagen and Denovo Biopharma to Develop Blood-Based CDx Test for Treatment of Diffuse Large B-Cell Lymphoma
QIAGEN N.V. (Venlo, Netherlands) and Denovo Biopharma LLC (San Diego, CA, USA) have entered into a collaboration to develop a blood-based companion diagnostic (CDx) test to identify patients expressing Denovo Genomic Marker 1 (DGM1TM) who are likely to respond to Denovo’s investigational cancer drug DB102TM for treatment of diffuse large B-cell lymphoma (DLBCL), one of the most common lymphoid cancers. More...21 Dec 2021
Pulmonary Eosinophilia Indicates Onset of Allergic Bronchopulmonary Aspergillosis
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder caused by type 2 immune responses to Aspergillus. This pathology usually develops after the onset of bronchial asthma (BA) or cystic fibrosis. Rates differ among countries, but appear to be increasing around the world with the increase of BA. More...13 Dec 2021
Immunoprofiling HTLV-1 Blood Samples Show Altered Innate Cell Responsiveness
The Human T-cell Leukemia Virus-1 (HTLV-1)-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) is a progressive neurodegenerative disease characterized by the demyelination of the middle-to-lower thoracic cord. More...09 Dec 2021
Classification of Mature B-Cell Neoplasms Employing Standardized Flow Cytometry
The classification of lymphoid neoplasms integrates clinical, pathological, immunophenotypic, genetic, and molecular data in order to distinguish between mature B-cell lymphoma entities. The precise classification of these entities (also known as B-cell chronic lymphoproliferative diseases, B-CLPD) has relevant therapeutic implications. More...08 Dec 2021
Monocyte Distribution Width Predicts Sepsis in Critically Ill Patients
Sepsis has been reported as a major cause of increased morbidity, length of stay and mortality among patients hospitalized in Intensive Care Units (ICUs) for any cause. The survival of patients developing sepsis in the ICU is strictly related to an early diagnosis, as well as a prompt start of appropriate medical interventions. More...06 Dec 2021
Multiple Coagulation Parameters Predict Postoperative Bleeding Volume in Cardiovascular Surgery
Coagulopathy and massive bleeding are severe complications of cardiovascular surgery, particularly occurring after procedures requiring prolonged cardiopulmonary bypass (CPB). During surgery massive transfusion of blood products may become necessary. More...02 Dec 2021
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
