Hematology
Unique Diagnostic Test Based on Mass Spectrometry Technique Accurately Identifies Early-Stage Alzheimer's Disease
Cerebral amyloid load is one of the first signs of early-onset Alzheimer's Disease (AD) in individuals with subjective memory complaints (SMCs) and has potential for use as a biomarker to indicate how the condition evolves. A new assay based on mass spectrometry has shown to be capable of quantifying amyloid-beta 40 and 42 proteins – both associated with the risk of having AD – in plasma samples. More...16 Mar 2022
ELISA Blood Test Uses Innovative Biomarker to Detect Heart Disease and Sudden Cardiac Arrest
The CardiNor SN assay from Cardinor AS (Oslo, Norway) is a blood-based cardiovascular risk test that detects SN, a small 33-amino acid neuropeptide detectable in the blood stream and produced by neuroendocrine and heart muscle cells. SN is the only biomarker shown to be associated with biological processes linked to cardiomyocyte handling and has been described as the “missing link biomarker” in CVD risk assessment. More...15 Mar 2022
Clinical Application of Leukocyte Counts Based on Targeted DNA Methylation Analysis
Differential leukocyte counts are usually measured based on cellular morphology or surface marker expression. It has recently been shown that leukocyte counts can also be determined by cell-type–specific DNA methylation (DNAm). Such epigenetic leukocyte counting is applicable to small blood volumes and even frozen material, but for clinical translation, the method needs to be further refined and validated. More...14 Mar 2022
Nova Biomedical Launches CE-Marked Nova Max Pro Creatinine/eGFR Meter for Kidney Function Screening
Nova Biomedical (Waltham, MA, USA) has launched the Nova Max Pro Creatinine/eGFR Meter System in all CE countries. Nova Max Pro is an important new tool to improve kidney care through kidney function screening and early detection of kidney disease in point-of-care settings outside the hospital. More...14 Mar 2022
Rapid POC Blood Ammonia Detector Could Dramatically Decrease Processing Times from Hours to Minutes
Aza Technology Inc. has developed a Rapid Ammonia Monitoring Device (AMD) intended for the quantitative determination of ammonia in whole blood, which enables the early detection of hyperammonemia that is critical to prevent irreversible neurological damage, coma, and death. The AMD can be lifesaving as it aims to dramatically decrease blood ammonia processing times from hours to minutes. More...14 Mar 2022
Blood Test Can Estimate Presence of Alzheimer’s Disease Changes and Blood Vessel Damage in the Brain
Due to recent technological developments, blood-based biomarkers of disease are now available and researchers from the Sanders-Brown Center on Aging at the University of Kentucky (Lexington, KY, USA) believe they could be beneficial in the diagnosis of Alzheimer’s and other dementias. A biomarker – short for biological marker – is a measurable indicator that captures what is happening in a cell or an organism at a given moment. More...11 Mar 2022
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In Other News
Molecular and Cytogenetic Characterization of Myelodysplastic Syndromes in Cell-Free DNA
Mitochondrial Damage May Explain the Increased Incidence of Hypertension in Black Adults
Simple Blood Test to Address Unmet Need in Alzheimer’s Disease Detection
Fujirebio Launches Neurodegeneration Assay for Automated Blood-Based Alzheimer’s Disease Biomarker Testing
First Approved Blood Test Predicts Likely Progression to Alzheimer's Up to Six Years in Advance
High-Risk Subtype of Relapsed Pediatric Acute Myeloid Leukemia Revealed
First-of-its-Kind Blood-Based Pan Cancer Early Detection Test Combines Protein Markers, Genomic and Epigenetic Features of Cancer in Blood
Coagulation Analyzers Evaluated and Compared in Coagulation Laboratory
Biomarker Panel for Risk of Early Respiratory Failure Following Hematopoietic Cell Transplantation
Micro-Mechanical Blood Clot Testing Using Smartphones
Revolutionary Test Enables Precision-Guided Dosing for Inflammatory Bowel Disease
Histological Criteria Predicts Lymphoma Transformation in Bone Marrow Biopsies
10-Minute Sepsis Risk Test Could Change the Way Emergency Departments Recognize and Treat Sepsis
Certain Childhood ALL Subtypes Linked to Genetic Ancestry
Microfluidic Gated Device for Extraction of Cell-Free DNA Could Help Accurately Diagnose Infections from Small Blood Sample
Automating Blood Smears Developed for Easier Malaria Diagnosis
Transcriptomic Analysis Reveals Proinflammatory Signatures Associated with AML Progression
Stago Launches New My Qualiris QC Website for Brand-New User Experience
New One-Step Test Screens for Three Rare Genetic Disorders Simultaneously In Newborns
Hematologic Complications with Age in Shwachman-Diamond Syndrome
Cord Blood and Matched Related Donor Transplantation Compared in Acute Myeloid Leukemia
New Technology That Automates Blood Smears to Help Labs Accurately Diagnose Bloodborne Diseases
ddPCR Developed for BCR-ABL1 Fusion Transcript in B-Lymphoblastic Leukemia
The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.