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Hematology

Image: The rapid, automated, highly sensitive “STA-Liatest D-Di” – the first D-dimer assay for exclusion of pulmonary embolism to meet the FDA’s approval requirements now based on the new, higher standards established by the Clinical Laboratory Standards Institute (Photo courtesy of Diagnostica Stago).

D-dimer Assay for Exclusion of Pulmonary Embolism First to Meet Advanced Standards

For the first time a D-dimer assay for exclusion of pulmonary embolism meets the US Food and Drug Administration’s approval requirements now based on the new and more restrictive standards established by the Clinical Laboratory Standards Institute.  More...
01 Oct 2014
Image: Close-up of a prototype device for point-of-care testing of anemia. The device could enable more rapid diagnosis of the common blood disorder and allow inexpensive at-home self-monitoring of persons with chronic forms of the disease (Photo courtesy of Emory University).

Rapid Anemia Test Compares Favorably with Hospital Hemoglobin Analyzers

A prototype point-of-care testing device for anemia was evaluated and found to deliver results compatible with those obtained on a hospital hematology analyzer.  More...
23 Sep 2014
Image: The topography of a red blood cell as measured by the spatial light interference microscope (SLIM) optical technique. Though the cell keeps its shape as it ages, the membrane becomes less flexible (Photo courtesy of Prof. Gabriel Popescu).

Optical Interferometry Assays Stored Erythrocyte Function

The effect of the storage on the erythrocyte membrane deformability and morphology has been investigated using optical interferometry which can image red blood cell topography with nanometer sensitivity.  More...
16 Sep 2014
Image: Researchers have demonstrated potential for a new, noninvasive method to screen for prostate cancer using a detection system that combines surface-enhanced Raman scattering (SERS) with support vector machine (SVM) techniques (Photo courtesy of Prof. S. Li and Guangdong Medical College).

Novel Method Developed for More Effective Noninvasive Prostate Cancer Screening

Comparing healthy volunteers and prostate cancer patients, researchers have successfully shown that their new method, which builds on the use of SERS spectroscopy of silver nanoparticles mixed with blood samples, could reveal cases of cancer.  More...
16 Sep 2014
Image: Photomicrograph of a blood film from a patient with atypical chronic lymphocytic leukemia. Lymphocytes were primarily small with round nuclei, condensed chromatin and scant cytoplasm. Approximately 20% of the lymphocytes had the morphologic features of prolymphocytes with finely dispersed chromatin and central nucleoli (arrows) (Photo courtesy of the American Society of Hematology).

Atypical Chronic Lymphocytic Leukemia Identified by Digital Microscopy

Digital microscopy has been used to morphologically classify chronic lymphocytic leukemia patients as atypical chronic lymphocytic leukemia or typical CLL, and determine the prevalence of prognostic markers in each group.  More...
09 Sep 2014
Image: Scientists have developed a simple new test for sickle cell disease that provides results in just 12 minutes and costs as little as USD 0.5 — far simpler, faster, and cheaper than current tests (Photo courtesy of Dr. A. Kumar and Harvard University).

Novel Diagnostic Test Developed for Sickle Cell Disease

Researchers have developed a simple, rapid, low-cost test for sickle cell disease that could enable large-scale global screening also of children in underprivileged regions, such as those in Africa and India.  More...
08 Sep 2014
Image: The fluorescence-activated cell sorting FACSCanto II flow cytometer (Photo courtesy of BD Biosystems).

Flow Cytometry Detects Lymphoproliferative Disorders in Fluid Specimens

Immunophenotypic analysis of hematopoietic cell populations by flow cytometry has emerged as a useful ancillary study in the diagnostic evaluation of serous effusions and cerebrospinal fluids.  More...
26 Aug 2014
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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